Phase 3 N=261 Obese Hypertension Study (0954-315)
Hypertension
Primary: Mean Change From Baseline in Trough Sitting Systolic Blood Pressure (SiSBP) at Week 8 — -12.1; -6.8 mm Hg
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=9,361 Systolic Blood Pressure Intervention Trial
Hypertension
Primary: Number of Participants With First Occurrence of a Myocardial Infarction (MI), Acute Coronary Syndrome (ACS), Stroke, Heart Failure (HF), or CVD Death — 243; 319…
Phase 4 N=229 The Effects of Systolic Blood Pressure Lowering on Diastolic Function Using Valsartan + Amlodipine in Patients With Hypertension and Diastolic Dysfunction
Hypertension · Diastolic Dysfunction
Primary: Change in Lateral Mitral Annular Myocardial Relaxation Velocity — 1.544; 1.476 cm/s
N/A N=126 Blood Pressure in Dialysis Patients
Hypertension · Renal Failure Chronic Requiring Hemodialysis · Blood Pressure
Primary: Number of Participants Assessed for Intensive (110-140 mm Hg) and Standard (155-165mm Hg) Pre-dialysis Standardized BP Goal — 62; 64 participants
N/A N=5 HIRREM for Stage 1 Primary Hypertension
Hypertension · Blood Pressure · Cardiovascular Diseases
Primary: Change From Baseline in Blood Pressure, as Measured by an Automated Oscillometric Blood Pressure Device. — -3.00; -6.67; -6.00; -7.67 mmHg
N/A N=510 Blood Pressure Checks for Diagnosing Hypertension (BP-CHECK)
Blood Pressure
Primary: Comparative Performance of Clinic, Home, and Kiosk — -4.7; -0.1; 9.5; -7.2 millimeters of mercury — p=<0.05
N/A N=200 Perioperative Blood Pressures and Chronic Hypertension
Hypertension
Primary: Performance of Blood Pressure Referral Threshold — .841 proportion
Phase 4 N=488 Valsartan/Amlodipine As Compared to Losartan Treatment in Stage 2 Systolic Hypertension
Stage 2 Systolic Hypertension
Primary: Change in Mean Sitting Systolic Blood Pressure After 6 Weeks — 166.8; 168.5; 135.5; 142.5 mmHg
N/A N=123 Pre-clinical Cardiac Dysfunction Among Asymptomatic Hypertensive Patients
Hypertension · High Blood Pressure · Ventricular Hypertrophy
Primary: Clinically Significant Difference in Blood Pressure Lowering, Health Status and Quality of Life — -3.3; -4.9 mm Hg
N/A N=51 Chiropractic for Hypertension in Patients
Hypertension
Primary: Unadjusted and Adjusted Changes From Baseline in Systolic and Diastolic Blood Pressure at Weeks 1, 3, 6 — -1.2; -5.3; 0.8; -1.7 mmHg
N/A N=56 Mindfulness Based Stress Reduction for High Blood Pressure
Hypertension
Primary: SBP — 130.2; 128.8 mm Hg
N/A N=591 Hypertension Intervention Nurse Telemedicine Study (HINTS)
Hypertension
Primary: Estimated Percentage of Participants in Blood Pressure Control at Baseline — 61; 59; 53; 64 % of particpants w/ controlled BP
Phase 4 N=433 Nebivolol in Patients With Systolic Stage 2 Hypertension
Hypertension
Primary: Change From Baseline in Mean Seated Systolic Blood Pressure After 6 Weeks of Nebivolol Monotherapy — -18.2; -12.3 mm Hg
N/A N=199 Intensive Versus Standard Blood Pressure Lowering to Prevent Functional Decline in Older People
Hypertension, Systolic · Cerebrovascular Disease
Primary: Mobility - Measured by Change in Gait Speed — 0.4; 0.42 seconds
N/A N=542 Helping Hypertension Patients to Interpret Blood Pressure Readings and Motivate Blood Pressure Control
Hypertension
Primary: Number of Participants Who Measured Blood Pressure as Instructed (Assessed on Questionnaire) — 34; 47; 50 Participants — p==0.05
Phase 4 N=24 Metabolic Effects of Antihypertensive Drugs on People With Metabolic Syndrome (The MEAD Study)
Hypertension
Primary: Change in Oral Glucose Tolerance Test (OGTT) Area Under Curve (AUC) After Addition of Trandolapril to Hydrochlorothiazide (HCTZ) Compared With Change in OGTT AUC After…
N/A N=146 The Effect of Pre-discharge Blood Pressure of Patients With Asymptomatic Severe Hypertension in Emergency Department
Hypertension · Emergencies · Asymptomatic Conditions
Primary: Number of Participants Who Died Within 7 Days After Discharge From the Emergency Department — 0; 0 participants
N/A N=574 Targeting of UnControlled Hypertension in Emergency Department
Hypertension · Cardiovascular Diseases · Vascular Diseases
Primary: Mean Systolic Blood Pressure (SBP) Difference at 6 Months Post-intervention Compared to Usual Care. — -9.2; -14.0 mmHg
N/A N=202 Pregnancy-Related Hypertension: Adherence to a New Type of Monitoring
Gestational Hypertension · Preeclampsia · Chronic Hypertension With Pre-Eclampsia Complicating Childbirth
Primary: Adherence to the American College of Obstetricians and Gynecologists Guideline of Postpartum Blood Pressure Check Within 10 Days Postpartum — 59; 89 Participants…
Phase 4 N=50 Effects of the Beta-blocker Nebivolol (Bystolic) on Subjects With High Normal Blood Pressure and/or a Family History of Hypertension
Pre-hypertension · Hypertension
Primary: Aortic Systolic Blood Pressure (SBP) — 112.7; 107.7; 106.2; 106.6 mm Hg
N/A N=206 Remote Surveillance of Postpartum Hypertension
Hypertension in Pregnancy
Primary: Number of Participants Whose Blood Pressure Was Assessed in the First Ten Days Following Discharge — 45; 95 Participants
N/A N=271 Effect of Reducing Sedentary Behavior on Blood Pressure
Hypertension · Prehypertension
Primary: Resting Systolic Blood Pressure — 129.5; 127.9; 124.3; 123.6 mm Hg
N/A N=17 Controlling and Lowering Blood Pressure With The MOBIUSHD™
Hypertension
Primary: Adverse Events — 1; 1; 1; 1 participants
Phase 1 N=31 A Study of the Effect of MK-8457 on Blood Pressure in Hypertensive Participants (MK-8457-004-AM1)
Hypertension
Primary: Change From Baseline to Day 10 in 24-hour Mean Ambulatory Systolic Blood Pressure (SBP) — -0.47; -2.49 mmHg
N/A N=385 Titrated Disease Management for Patients With Hypertension
Hypertension
Primary: Systolic Blood Pressure — 143.5; 143.7 mmHg
N/A N=9 Spinal Cord Stimulation to Treat Hypertension
Hypertension
Primary: Change in Exercise Pressor Reflex From Baseline — 8.67; 16.29 mmHG
Phase 2 N=85 Hypertension, Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial)
Hypertension
Primary: Changes in Gray Matter Intracranial Pulsatility — -0.09; 0.02 mm/cardiac cycle
N/A N=121 Self-management of Blood Pressure Medication for Hypertensive Veterans
Hypertension
Primary: In-clinic Blood Pressure Change — 136.0; 140.3; 126.9; 136.1 mm Hg — p=0.72
Phase 2 N=250 Treatment of Early Hypertension Among Persons Living With HIV in Haiti
HIV/AIDS · Pre Hypertension
Primary: Change in Mean Systolic Blood Pressure (SBP) — -10.58; -4.65 mmHg — p=<0.0001
N/A N=125 Self-Management and Resilience Trajectories in African American Adults With Hypertension
Hypertension · Self-Management · Quality of Life
Primary: Systolic Blood Pressure — 138.35; 135.56 mmHg — p=0.0050