30 closest matches · ranked by relevance
Low Back Pain
Primary: Numbers and Types of Adverse Events (Only Number of Events is Reported in This Section - See Adverse Events Section for Further Detail) — 17 Events
Sciatica · Back Pain
Primary: To Demonstrate a Statistically Significant Difference in the Relief of Back Pain Between Both Treatment Groups. The Endpoint Will be the Difference Between Baseline and…
Degenerative Disc Disease
Primary: Neurological Assessment for Motor Function and Reflexes/Sensory — 0; 0 participants
Degenerative Disc Disease
Primary: Overall Success at 24 Months Relative to Baseline — 42.2; 28.3; 61.9; 52.8 percentage of participants — p=<0.05
Lumbar Degenerative Disc Disease
Primary: Number of Participants With a Change of at Least 15 Points in Pain/Disability Using the Oswestry Disability Index (ODI) Score at 24 Months Compared With the Score at…
Degenerative Disc Disease · Intervertebral Disc Disease · Low Back Pain
Primary: Pain and Disability Evaluation — 0.28; 0.15 scores from 0 to 1
Degenerative Disc Disease · Lumbar Spondylosis · Low Back Pain
Primary: Pain Diary — 6.71; 5 units on a scale
Cervical Degenerative Disc Disease
Primary: Overall Success — 137; 110; 28; 13 participants who are successes
Back Pain
Primary: Change in Average Daily Pain Visual Analog Scale (VAS) Score Between Screening and Follow up. — -2.4; -0.56 units on a scale
Lumbar Disc Herniation
Primary: Change From Baseline to Week 13 in Average Worst Leg Pain Score During the Past 24 Hours Over the Previous 7 Days — -41.7; -34.2 units on a scale — p=0.0263
Degenerative Disc Disease
Primary: Neurological Assessment for Motor Function and Reflexes/Sensory — 0; 0 participants
Degenerative Disc Disease
Primary: Composite Definition of Study Success — 65.3; 73.7; 37.4; 69.7 percentage of subjects analyzed — p=0.0021
Lumbar Degenerative Disc Disease
Primary: Number of Subjects With Successful Radiographic Fusion — 90 Participants
Lumbar Spondylolisthesis · Degenerative Disc Disease · Degenerative Spondylolisthesis
Primary: Incidence of Successful Lumbar Fusion Measured Radiographically — 13; 11 Participants
Early Lumbar Disc Degeneration
Primary: Neurological Assessment for Motor Function and Reflexes/Sensory — 0; 0 participants
Cervical Degenerative Disc Disease
Primary: Number of Participants With Composite Clinical Success (CCS) of Simplify Disc — 68; 132 Participants — p=<.001
Spondylosis · Cervical Spondylosis · Spondylolisthesis
Primary: Fusion Rates Per Level Using the Bridwell Interbody Grading Scale — 64; 50 Fusions
Early Lumbar Disc Degeneration
Primary: Neurological Assessment for Motor Function and Reflexes/Sensory — 0; 2 participants
Symptomatic Cervical Disc Disease
Primary: Overall Success — 62.8; 53.2; 62.7 % of Subjects
Degenerative Disc Disease
Primary: Participants With Improved Patient Function — 7; 6 participants — p=1.0
Degenerative Disc Disease
Primary: Radiographic Fusion — 66; 46; 37; 75 percentage of subjects
Spine Fusion
Primary: Oswestry Disability Index — 41.3; 30.4; 19.4 score on a scale
Cervical Degenerative Disc Disease
Primary: Rate of Overall Success — 70.4; 63.2 percentage of participants — p=0.995
Low Back Pain
Primary: Difference in Number of Magnetic Resonance Imaging (MRI)-Positive Discs Diagnosed Positive by Provocative Discography (PD) and Functional Anesthetic Discography (F.A.D.)…
Chronic Low Back Pain
Primary: Change in the Numerical Pain Rating Scale — 5.96; 6.12; 6; 1.22 units on a scale
Lumbar Spinal Stenosis
Primary: Changes in Back Pain as Measured by a 10-point Visual Analog Scale (VAS). — 3.59 units on a scale — p=<0.0001
Lumbar Spinal Stenosis
Primary: Mean Change in Back Pain as Measured by a 10-point Visual Analog Scale (VAS). — 3.21 units on a scale — p=<0.0001
Spinal Diseases
Primary: Overall Success — 45.1; 63.5; 66.7; 53.3 percentage of overall successes
Cataract · Floppy Iris Syndrome
Primary: Corneal Endothelial Cell Loss — 9.85; -3.68 Percent change
Radiculopathy · Herniated Disk
Primary: VAS for Lumbar Pain in 3 Months — 2.63; 4.53 units on a scale — p=0.05