N/A N=10,100 Indication for Intraoperative Volume Therapy
Patients Undergoing Any Kind of Surgery
Primary: Number of Different Substitution Solutions Administered — 7827; 1055; 221 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=23 Bedside Resources to Gauge Intravascular Volume Status
Hypovolemia · Craniosynostoses
Primary: Utility of Compensatory Reserve Index (CRI) Which Ranges From 0-1 in Order to Predict Fluid Responders From Non-responders — 0.06; 0.05 units on a scale
N/A N=30 Atrial Natriuretic Peptide in Assessing Fluid Status
Fluid Overload · Fluid Loss · Volume Overload
Primary: Number of Patients With Pro-ANP Twofold Raise by the End of Surgery — 17 Participants
Phase 3 N=59 Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables
Anesthesia
Primary: Change in Base Deficit — -1.5; -1.2; -0.5 mEq/L
N/A N=429 Predict Fluid Responsiveness in Spinal Anesthesia
Hypotension and Shock · Excessive Amount of Blood / Fluid Infusion
Primary: Percentage of Participants With Systemic Hypotensions — 68; 46; 65 Participants
N/A N=10 Blood Volume and Fluid Kinetics in Patients Undergoing Extracorporal Circulation
Blood Volume, Extravasation
Primary: Blood Volume — 4.61 Litre
N/A N=94 A Prospective Study Evaluating the Use of Intraoperative Stroke Volume Variation Via the FloTrac Device to Guide Fluid and Vasopressor Management in Head and Neck Free Flaps
Head and Neck Cancer · Patients Requiring a Free Flap Surgery
Primary: ICU Stay — 33.7; 58.3 hours
N/A N=86 Using Electrical Bioimpedance Assessments to Estimate Perioperative Total Body Water and Postoperative Fluid Need
Intestinal Cancer · Diverticulitis · Pancreatic Cancer
Primary: Bioimpedance Assessment — 0.53 ohms
N/A N=68 Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients
Intracranial Aneurysm · Brain Edema · Scoliosis
Primary: Number of ICU Stays Greater Than 1.5 Days — 13; 20 Number of ICU Stays greater that 1.5 Day
N/A N=160 Can Vena Cava Ultrasound Guided Volume Repletion Prevent Spinal Induced Significant Hypotension in Elective Patients?
Fluid Overload · Anesthesia; Adverse Effect, Spinal and Epidural · Regional Anesthesia Morbidity
Primary: Rate of Arterial Hypotension — 42.5; 27.5 percentage of participants
N/A N=14 Blood Volume Analysis of Total Hip Arthroplasty Patients Under Hypotensive Anesthesia
Blood Volume Analysis
Primary: Change in Total Blood Volume — 487 ml
N/A N=46 Arterial Pulse Waveform Contour Analysis for Intraoperative Goal Directed Therapy in Major Abdominal Surgery
Surgical Procedures, Operative
Primary: Length of Postoperative Hospital Stay — 7.5; 5.0 Days
N/A N=16 Volume Restriction in Esophageal Carcinoma Surgery: Randomized Clinical Trial
Esophageal Neoplasm
Primary: Pulmonary Gas Exchange During and After Esophageal Carcinoma Surgery (PaO2/FiO2 Ratio) — 345.01; 330.11; 315.51; 307.11 mmHg — p=0.410
N/A N=50 The Effect of Goal-directed Therapy Guided by Stroke Volume Variation and Cardiac Index in Non-severe Surgical Patients
Fluid Therapy
Primary: Number of Days Needed for Anal Exsufflation After Surgery — 3.8; 2.7 days
N/A N=10 Volume Kinetics for Starch Solution and Acetated Ringers
Blood Volume · Blood Coagulation
Primary: Volume Effects for Hydroxyethyl Starch, Ringer's Solution or a Combination of Both. — 5.53; 2.94; 3.12; 4 Litre
Phase 3 N=135 Clinical Trial of Standard Versus Goal-Directed Perioperative Fluid Management (GDT) for Patients Undergoing Liver Resection
Liver Cancer
Primary: Postoperative Complications — 42; 45; 24; 24 Participants
N/A N=212 Guidance of Ultrasound in Intensive Care to Direct Euvolemia
Acute Kidney Injury
Primary: Number of Acute Kidney Injury (AKI)-Free Days — 1; 1 Days
Phase 4 N=55 Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy
Esophageal Diseases · Gastrointestinal Diseases · Disorder of the Genitourinary System
Primary: Length of Hospital Stay (LOS) by Participant
N/A N=40 Closed-Loop Fluid Administration System Using Hemodynamic Monitors
Intraoperative Volume Status · Postoperative Complications
Primary: Fluid Status During Surgery — 95 percentage of case time
N/A N=30 Pleth Variability Index (PVI) as a Measure of Volume Status During Transcatheter Mitral Valve Repair
Mitral Regurgitation
Primary: Delta PVI to Delta LAP Correlation During MitraClip Placement — 4.30; -26.14 percentage of baseline (pre-MitraClip) — p=0.066
N/A N=160 Effect of Intraoperative Crystalloid Volume on Postoperative Vomiting
Postoperative Vomiting
Primary: Postoperative Vomiting — 11; 9; 66; 68 participants — p=0.05
Phase 4 N=58 Improvement of Fluid Balance in Patients Undergoing Surgery of the Colon and Rectum
Colorectal Carcinoma
Primary: Peak Value of I-FABP — 440.8; 522.4 pg/mL
N/A N=82 Fluid Balance in the ICU - Interventions to Minimize Fluids in Patients With Septic Shock
Septic Shock · Fluid Therapy · Hypotension
Primary: Cumulative Fluid Administered — 4417; 4110 mL of study fluid
Phase 3 N=149 Use of 6% Hydroxyethylstarch (130/0.4) in Cardiac Surgical Patients
Postoperative Kidney Injury
Primary: Urine Neutrophil Gelatinase-associated Lipocalin (NGAL) [Time Frame: 24 Hours After Surgery] [Designated as Safety Issue: Yes] — 2.9; 4.0; 5.0; 4.7 ng/ml — p=0.15
N/A N=1,102 Effect of Goal-directed Crystalloid Versus Colloid Administration on Major Postoperative Morbidity
Postoperative Complications
Primary: Number of Participants With Postoperative Morbidity (Major Complications) — 103; 91 Participants — p=0.51
N/A N=52 Does Fluid Replacement From Preoperative NPO Status Improve Postoperative Recovery
Osteoarthritis
Primary: Number of Participants With Postoperative Complications — 0; 1; 0; 0 participants
N/A N=150 Traditional vs Oral Fluid Management in Total Knee Arthroplasty
Arthroplasty, Replacement, Knee
Primary: Body Weight — -1.9; -1.6 pounds
N/A N=40 Transcutaneous pO2, Transcutaneous pCO2 and Central Venous SO2 Variations to Define Fluid Responsiveness
Hypotension · Shock · Fluid Challenge
Primary: Fluid Responsiveness — 18 Participants
N/A N=3,000 REstrictive Versus LIbEral Fluid Therapy in Major Abdominal Surgery
Major Abdominal Surgery
Primary: Number of Participants With Disability-free Survival — 1232; 1223 Participants
N/A N=150 Fluid Responsiveness Evaluation in Sepsis-associated Hypotension
Sepsis · Hypotension
Primary: Fluid Balance — 0.65; 2.02 Liters — p=0.021