N/A N=100 Patient Education on Labor Analgesia Options
Labor Analgesia
Primary: Survey to Determine Utility and Effect of Educational Materials — 79; 21; 93; 7 percentage of patients responding — p=<0.0001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=818 Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery
Labor Pain · Pregnancy
Primary: Delivered by Cesarean Section — 134; 126 participants — p=0.65
N/A N=57 Does Maternal Fever During Labor Analgesia Has Any Relationship With Maternal Ventilation?
Pregnancy
Primary: Changes in Maternal Ventilation During Labor Analgesia — 15.3; 12.6; 13.8 L/min
Phase 4 N=41 Effect of Preemptive Epidural Analgesia in Labor on Cytokine Production
Obstetric Pain
Primary: Maternal Cytokine IL-10 Levels of pg/ml Upon Enrollment — 12.7; 14.2 pg/ml
Phase 2 N=22 Intrathecal Hydromorphone for Labor Analgesia
Labor Pain
Primary: Pain Score, Visual Analogue Pain Scores — 1.9 units on a scale
Phase 4 N=46 Transcutaneous Electrical Nerve Stimulation for Pain Relief During the Active Phase of Labor
Pain
Primary: Classification of Pain During Labor by Visual Analogue Scale — 57.0; 72.1 mm — p=0.01
Phase 4 N=67 Infiltration Analgesia After Caesarean Section
Pain, Postoperative · Caesarean Section
Primary: The Demand of Rescue Analgesics (Oxycodone) — 47.5; 57.8 mg — p=0.10
Phase 3 N=75 Comparing Bupivacaine, Lidocaine, and a Combination of Bupivacaine and Lidocaine for Labor Epidural Activation
Labor Pain
Primary: Time to Achieve an Adequate Epidural Level for Labor Analgesia — 7.0; 11.0; 8.5 minutes
N/A N=220 Association Between Bolus Rate and the Adequacy of Labor Analgesia Using Timed-intermittent Boluses
Labor Pain · Obstetric Pain
Primary: Number of Participants Who Experienced Breakthrough Pain. — 37; 43 Participants — p=.67
Phase 4 N=101 Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain
Labor Pain
Primary: Number of Subjects With Success Rate at 15 Minutes Post-epidural Bolus Injection — 31; 38 Participants — p=0.38
Phase 4 N=80 Spinal or Epidural Fentanyl or Sufentanil for Labour Pain in Early Phase of the Labour
Labor Pain
Primary: Change of Maximum Pain During Contraction at 20 Minutes After the Study Drug Delivery — 60; 36; 67; 42 mm
Phase 4 N=179 Comparison of PIEB vs CEI for Labor Analgesia
Labor Pain
Primary: Volume of Local Anesthetic Received Through Patient Controlled Epidural Analgesia (PCEA) Per Hour — 4.03; 4.52 milliliters per hour — p=0.17
N/A N=150 Presence of a Companion During Performance of Neuraxial Labor Analgesia
Anxiety · Pain · Health Knowledge, Attitudes, Practice
Primary: Maternal Satisfaction and the Presence of a Companion During the Placement of Epidural Catheter for Labor Analgesia. — 2; 2; 3; 0 Participants — p=.001
N/A N=80 Non-pharmacological Resources in Assisting Labor
Labour Pain
Primary: Pain Relief — 79.5; 73.8; 71.0; 51.7 millimeters
Phase 4 N=46 Massage for Pain Relief During the Active Phase of Labor
Pain
Primary: Effectiveness of Massage Therapy in Pain Relief During Labor. — 68.7; 69.0; 72.1; 51.7 milimeters
Phase 2 N=88 Effectiveness of Clonidine, Dexmedetomidine, and Fentanyl Adjuncts for Labor Epidural Analgesia
Pregnancy Related
Primary: Pain Burden, AUC (30 Minutes) — 101; 67; 39 pain units*minutes — p=0.226
Phase 4 N=41 Remifentanil as Intravenous Patient-controlled Analgesia (IVPCA) During Labour
Labour Pain · Satisfaction · Adverse Effects
Primary: Pain Score, Visual Analogue Scale (VAS) (Mean Maximal Change in Pain) — 47 millimeters
N/A N=204 Use of Peanut Labor Ball Following Epidural Anesthesia
Pregnancy
Primary: Delivery Rate — 31; 21 participants
Phase 1 N=200 Epidural Neostigmine for Labor Pain
Labor Pain
Primary: Amount of Drug Consumed Per Hour in Each Group(Arm) — 16.2; 14.6; 15.3; 16 milliliters per hour
N/A N=345 The Effect of Neuraxial Analgesia on Maternal Breastfeeding
Pain · Breastfeeding
Primary: Breastfeeding at 6 Weeks Post Delivery — 100; 99; 102; 3 Participants — p=.34
N/A N=303 Acupuncture With Manual and Electrical Stimulation to Reduce Labour Pain
Labour Pain
Primary: Use of Epidural Analgesia — 99; 103; 101 participants
N/A N=80 The Maternal and Perinatal Outcomes Associated With the Use of Non-pharmacological in Labor
Pain
Primary: Number of Participants Who Requested Analgesia During the Active Phase of Childbirth — 37; 35 Participants
N/A N=76 Local Anesthesia and Pain Perception During an Amniocentesis
Pregnancy
Primary: Intensity of Perceived Maternal Pain as Measured by the Visual Analogue Scale (VAS) — 9.5; 18.4 units on a scale
Phase 3 N=79 Liposomal Bupivacaine at Cesarean Delivery to Decrease Post-operative Pain
Pain, Postoperative
Primary: Pain Score With Activity — 3.5; 4 units on a scale — p=0.72
Phase 4 N=60 Obstetric Liposomal Bupivacaine Via Surgical Transversus Abdominis Plane Block for Post Cesarean Pain Control
Cesarean Section Complications · Pain · Opioid Use
Primary: Total Opioid Usage in Oral Morphine Equivalents — 8; 2 morphine milligram equivalents
Phase 4 N=120 Multimodal Pain Management for Cesarean Delivery
Pain
Primary: Total Opioid Intake in Morphine Milligram Equivalents in the First 48 Hours After Cesarean Delivery (CD) — 42; 49.5 morphine milligram equivalents
Phase 4 N=84 Impact of Local Anesthetic Wound Infiltration on Postoperative Pain Following Cesarean Delivery
Pain
Primary: Pain Score on Movement (Sitting in Bed From a Supine Position) — 5; 5 score on a scale
Phase 4 N=101 Comparing Effectiveness of CSE Versus DPE for Labor Analgesia
Labor Pain
Primary: Number of Participants With the Presence of Any of the Five Block Quality Components (or More Than One) — 16; 13 Participants — p=0.486
Phase 3 N=192 Wound Infusion vs Spinal Morphine for Post-caesarean Analgesia
Post Caesarean Analgesia
Primary: Duration of Effective Analgesia — 351; 380; 247 minutes
Phase 4 N=44 2 Dose Neuraxial Morphine for Prevention of PDPH
Postdural Puncture Headache
Primary: Number of Participants With Postdural Puncture Headache — 3; 4; 8; 10 Participants