N/A N=12 Studies in Patients With Low Anterior Resection Syndrome (LARS)
Anterior Resection Syndrome · Bowel Dysfunction
Primary: Change of Anorectal Pressure Assessed With the Fecobionics Device — 9.8 cmH2O
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=52 Stapled TransAnal Rectal Resection (STARR) With Contour® TranstarTM
Obstructed Defecation Syndrome · Rectocele · Intussusception
Primary: Quality of Life — 3.2; 3.7; 2.8; 3.3 units on a scale — p=0.1340
Phase 4 N=75 Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstructive Defecation Syndrome (ODS)
Obstructive Defecation Syndrome · Chronic Constipation · Rectocele
Primary: Percentage of Change (Reduction) in Total ODS Symptom Composite Score From Baseline to One Year Post Procedure — 60.8 percentage of change
Phase 4 N=109 Prospective Randomized Controlled Trial of an Enhanced Recovery Protocol for Anorectal Surgery
Anorectal Disorder
Primary: Total Narcotic Use Postoperatively in Oral Morphine Equivalents — 8; 79 Oral morphine miligram equivalents
N/A N=121 The Role of Biofeedback in Improving Continence After Anterior Resection
Rectal Neoplasms · Fecal Incontinence · Aged
Primary: Cleveland Clinic Incontinence (CCI) Score — 4.2; 3.7; 1.2; -0.7 score on a scale — p=0.54
N/A N=32 Randomized Clinical Trial on Transanal Irrigation
Low Anterior Resection Syndrome
Primary: LARS Score — 21.3; 32.2 score on a scale
N/A N=31 Correlation of Anal Acoustic Reflectometry Parameters With Degree of Rectal Intussusception and Prolapse
Pelvic Floor Disorders
Primary: Opening Pressure — 56.35; 39.01; 23.42 cmH20
N/A N=40 Evaluation of the Rectal Reflex Using Anal Acoustic Reflectometry
Pelvic Floor Dysfunction
Primary: Opening Pressure — 34.44; 15.41 cmH2O
Phase 3 N=69 Rifaximin and Placebo in the Treatment of Bowel Dysfunction After Anterior Resection for Rectal Cancer
Rectal Cancer
Primary: Number of Participants Who Completed MSKCC Bowel Function Instrument (BFI Score) in Patients Following Anterior Resection (AR) or Sphincter Preserving Surgery (SPS) for…
Phase 3 N=486 Laparoscopic-Assisted Resection or Open Resection in Treating Patients With Rectal Cancer
Colorectal Cancer
Primary: Comparing Laparoscopic-assisted Resection to Open Rectal Resection for Rectal Cancer as Measured by the Percentage of Patients With Successful Resection Based on…
N/A N=57 Study of the Preservation of the Left Colic Artery on Rectum Cancer Surgery
Rectum Cancer
Primary: The Blood Pressure of the Arterial Arcade — 42.31; 48.50 mmHg
N/A N=97 Low Pressure Pneumoperitoneum and Deep Neuromuscular Block vs. Standard During RARP to Improve Quality of Recovery; a Randomized Controlled Study.
Quality of Life · Postoperative Complications · Acute Pain
Primary: Quality of Recovery - 40 Items Questionnaire Score (QoR-40) — 162.7; 167.6 score on a scale of 200 — p=0.54
Phase 2 N=124 Efficacy of Delayed Coloanal Anastomosis for Medium and Lower Rectum Cancer Treatment. Phase 2 Clinical Trial (CASCADOR)
Medium and Lower Rectal Cancer
Primary: Absence at Day 30 of a Symptomatic Anastomotic Leakage (AL) Among 2SCA — 1 Participants
N/A N=7 Fluorescent Evaluation of Colorectal Anastamoses
Rectal Neoplasms · Colon Neoplasms · Diverticulitis
Primary: Evaluate the Vascular Supply of the Bowel Intra-operatively and Correlate This With Postoperative Complications Identified During Their Hospital Stay at One Week and One…
Phase 3 N=104 Biological Mesh Closure of the Pelvic Floor After Extralevator Abdomino Perineal Resection for Rectal Cancer
Rectal Cancer
Primary: 30-day Uncomplicated Perineal Wound Healing — 30; 33 Participants
N/A N=130 Comparison Between End-to-side and Side-to-side Anastomosis After Laparoscopic Right Hemicolectomy
Anastomosis
Primary: Cumulative Recovery Rate — 100; 100 percentage of participants
N/A N=280 SANICS II Trial: Stimulation of the Autonomic Nervous System in Colorectal Surgery by Perioperative Nutrition
Postoperative Ileus · Anastomotic Leak
Primary: Number of Patients Developing Postoperative Ileus — 29; 37 Participants
N/A N=760 Observational Study of Anti-Reflux Surgery
GERD · Gastroesophageal Reflux · Gastro Esophageal Reflux
Primary: Gastroesophageal Reflux Disease Health Related Quality of Life Outcome (GERD-HRQL) — 4.2; 4.9 score on a scale
N/A N=142 Sexual Function and Wellbeing in Females With Rectal Cancer
Rectal Cancer
Primary: Change in Serum Testosterone Levels Between Baseline and 1 Year After Surgery. — 0.6; 0.6; 0.6; 0.5 nmol/l — p=0.004
N/A N=384 Post-resection Treatment of Large Colon Polyps
Recurrence
Primary: Recurrence — 10; 5; 24 Polyps
N/A N=178 Sexual Function and Wellbeing in Males With Rectal Cancer
Rectal Cancer
Primary: Change in Serum Testosterone Levels Between Baseline and After Preoperative Radiotherapy. — 11.3; 11.9; 9.3 nmol/L — p=0.014
N/A N=24 SafeHeal Anastomosis Feasibility Evaluation (SAFE)-2023 Study
Colorectal Cancer
Primary: Migration — 2 Participants
Phase 4 N=62 NITI CAR27 (ColonRing) Compression Anastomosis in Colorectal Surgery
Colonic Neoplasms · Rectal Neoplasms · Diverticulitis
Primary: Anastomotic Leakage — 0 participants
N/A N=12 Erectile Rating During the Treatment of Rectal Cancers Localized
Rectal Cancer Stage I
Primary: Proportion of Patients With Erectile Dysfunction Induced by Medical and Surgical Treatment of Rectal Cancer — 0 Participants
Phase 4 N=70 The Effect of Deep Neuromuscular Block on Surgical Condition During Laparoscopic Colorectal Surgery
Neuromuscular Blockade
Primary: Number of Participants With Increased Intra-abdominal Pressure (IAP) Alarm as > 15 mmHg — 14; 6 Participants
Phase 3 N=50 A Comparison of Targinact vs. Oxycodone on Gut Function After Colorectal Surgery
Postoperative Pain · Postoperative Nausea and Vomiting
Primary: Prevalence of Postoperative Gut Dysfunction — 13; 15 Participants — p=0.264
N/A N=7,050 Clinical Outcomes After Bowel Resection in Patients Receiving Alvimopan Versus Patients Not Receiving Alvimopan in the Premier Perspective Database
Ileus
Primary: Percentage of Patients Who Died — 0.4; 1.0 Percent of participants — p=0.0007
N/A N=198 Fast-track Rehabilitation After Elective Colorectal and Small Bowel Resection
Colorectal Tumor
Primary: the Length of Hospital Stay — 8; 7 day
N/A N=104 Spontaneous Void Requirements for Patients Undergoing Ambulatory Anorectal Surgery
Complications, Postoperative
Primary: PACU Time — 129.1; 210.0 Minutes
Phase 1 N=147 Perfusion Assessment in Laparoscopic Left Anterior Resection
Rectal Cancer · Colon Cancer · Crohn's Disease
Primary: PINPOINT System Utility in Left Colectomy Surgery — 11; 128 Participants