N/A N=71 Musculoskeletal Plasticity After Spinal Cord Injury
Spinal Cord Injuries
Primary: Acute Gene Regulation: MSTN — 5.49; 4.76 arbitrary units — p=<0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=23 Skeletal Muscle Atrophy and Dysfunction Following Total Knee Arthroplasty
Knee Osteoarthristis
Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared
N/A N=105 Prevention of Musculoskeletal Injuries in Slovenian Armed Forces
Knee Injuries and Disorders · Ankle Injuries and Disorders · Low Back Pain
Primary: Number of Soldiers With Ankle and Knee Injuries — 1; 3 Participants — p=0.134
N/A N=164 Extracardiac Complications After Cardiac Surgery
Acute Lung Injury · Sepsis · Infections
Primary: Acute Lung Injury After Cardiac Surgery — 20 participants — p=<0.05
N/A N=546 Inspiratory Strength and Respiratory Complications After SCI Injury
Spinal Cord Injuries · Pneumonia
Primary: Pneumonia — 70 Participants
Phase 1 N=10 In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome
Human Volunteers
Primary: Comparison Between INVOS Monitoring and Electromyography — 73; 46 % of StcO2
N/A N=330 Reducing the Transition From Acute to Chronic Musculoskeletal Pain Among Older Adults
Acute Musculoskeletal Pain · Chronic Pain
Primary: Mean Brief Pain Inventory-Short Form (BPI-SF) Combined Pain Severity and Interference Score — 2.67; 2.99; 2.94; 1.90 score on a scale — p=0.13
N/A N=42 Quantifying Myofascial Dysfunction in Post-Stroke Pain
Myofascial Dysfunction
Primary: T1 Rho MRI Relaxation Time of Shoulder External Rotator (Milliseconds) — 29.09; 27.15 milliseconds
N/A N=17 Palliative Strategies in Spinal Cord Injury (SCI)
Spinal Cord Injury
Primary: Muscle Mass Via Dual-Energy X-ray Absortiometry (DEXA)Scan Data — 6104.45; 6355.3 grams — p=.318
N/A N=47 Compression Stocking Use in Shoulder Arthroscopy in Beach Chair
Obesity · Shoulder Impingement
Primary: Cerebral Desaturation Event — 17; 22; 7; 1 Participants — p=.0553
N/A N=30 Skeletal Muscle Properties and the Metabolic Cost of Walking Post-stroke
Stroke
Primary: Oxygen Consumption During Walking — 11.25; 4.46 ml/kg/min
N/A N=33 The Effects of Spasticity on Glucose Metabolism in Individuals With Spinal Cord Injury
Spinal Cord Injuries
Primary: Correlation Between Knee Flexor Muscle Modified Ashworth Scale and Insulin Resistance — -0.692; 0.23 correlation coefficient — p=0.006
N/A N=33 Novel Intervention to Influence Muscle Plasticity in Veterans
Spinal Cord Injuries
Primary: HF Muscle Force — 23.9; 30.9 Newtons (N)
N/A N=1,002 The Maintaining Musculoskeletal Health Study
Widespread Chronic Pain
Primary: Development of Chronic Widespread Pain Assessed by Questionnaire — 69; 77 Participants
Phase 3 N=6 Effects of Electrical Stimulation and Vitamin D Supplementation on Bone Health Following Spinal Cord Injury.
Spinal Cord Injury
Primary: Change in Trabecular Plate Width (Tb.PW) for Femur and Tibia at 4.5 Months — 1785.42; 1819.41; 1805.52; 1834.67 μm
Early Phase 1 N=48 Serum Cartilage Oligomeric Matrix Protein Levels After 12 Weeks of Different Exercises
Osteoarthritis · Articular Cartilage Disorder of Knee · Degenerative Lesion of Articular Cartilage of Knee
Primary: Changes in Serum COMP Accumulation, Triggered by Acute Exercise, After 12 Weeks of Different Regular Exercises — -1.60; -0.53; -0.19; -0.12 U/l
N/A N=731 Impact of Deep Versus Standard Muscle Relaxation on Intra-operative Safety
Neuromuscular Blockade · Rocuronium · Anesthetics
Primary: Classic Score>1 — 66; 54 participants
Phase 2 N=25 Prevention of Skeletal Muscle Adaptations to Traumatic Knee Injury and Surgery
Anterior Cruciate Ligament Reconstruction
Primary: Cross-sectional Area of Skeletal Muscle Fibers (All Fibers) — 2827; 3318; 2206; 2376 micrometer squared — p=<0.05
N/A N=104 Multidisciplinary Evaluation of Patients With Hemophilia
Haemophilia
Primary: Assess the Joint Damage — 0.36; 0 points
Phase 4 N=100 Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery
Neuromuscular Blockade · Postoperative Complications
Primary: Number of Participants With Postoperative Pulmonary Complications — 8; 8 Participants — p=1.00
N/A N=38 Strength Training for Skeletal Muscle Adaptation After Stroke
Stroke
Primary: Change in 1-repetition Maximum (RM) Muscle Strength (Leg Press, Paretic Side) — 126.1; 11.3 lbs
Phase 2 N=244 Musculoskeletal Effects of Bicarbonate
Muscle Loss · Fractures · Osteoporosis, Age Related
Primary: The Dose of Potassium Bicarbonate Needed for Maximal Suppression of 24-hr Urinary N-telopeptide — 240; 230; 241; -53 nmol/day
N/A N=30 Wrist Fracture Evaluation With a Desktop Orthopedic Tomosynthesis System
Fracture
Primary: Sensitivity — 96.7 percent of scans with a fracture
N/A N=27 Muscle Weakness and Post-traumatic Knee OA
Meniscectomy
Primary: Change in International Knee Documentation Committee (IKDC) Subjective Knee Form Score — 22.2; 20.6 units on a scale
N/A N=89 Long Duration Activity and Metabolic Control After Spinal Cord Injury
Spinal Cord Injuries
Primary: Acute Gene Regulation: NR4A3 mRNA Expression Pre and Post-Stimulation — 3.235; 2.711; 6.286; 5.772 arbitrary units — p=<0.001
N/A N=40 Muscle Property, Alignment and Joint Loading in People With Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change of External Knee Adduction Moment as Assessed by Visual Motion Analysis System — 0.50 Nm/kg
Phase 4 N=240 Orphenadrine and Methocarbamol for LBP
Low Back Pain
Primary: Functional Impairment as Measured on the Roland Morris Disability Questionnaire — 10.9; 9.4; 8.1 units on a scale
N/A N=14 Vascular Dysfunction During Physical Inactivity
Aging · Vascular Endothelium · Skeletal Muscle
Primary: Brachial Artery Vascular Function — 5.1; 3.1; 4.4 percent vasodilation
Phase 4 N=12 Skeletal Muscle and Adipose Tissue Study
Idiopathic Scoliosis
Primary: Unbound Cefazolin Concentration in Skeletal Muscle — 3.22; 5.84 µg/ml/kg
N/A N=20 Preventing the Loss of Muscle and Function in Hospitalized Older Adults
Muscular Atrophy
Primary: The Percent Change in Bilateral Thigh Lean Mass Density (Grams) as Measured by DEXA Scan Will be Compared Between Baseline and After 5-days of Bed Rest — -3.845; -0.249…