N/A N=7 Impact of Direct Current Electrical Stimulation on Spasticity Levels and Functional Muscle Use in MS
Multiple Sclerosis
Primary: Expanded Disability Status Score — 6.8 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=50 Effect of Tetanus on Neuromuscular Junction Monitor Performance in Pediatric Patients
Muscle Relaxation
Primary: Train of Four 0,9 (90%) — 49.9; 41.7 minutes
N/A N=29 Neuromuscular Electrical Stimulation and Mobility in Multiple Sclerosis
Multiple Sclerosis
Primary: Walking Endurance — 42; 25 meters
N/A N=93 Neuroplastic Mechanisms Underlying Augmented Neuromuscular Training
Anterior Cruciate Ligament Injuries
Primary: Neural Mechanisms for Injury-resistant Movement Pattern Acquisition — 0.28; 0.26; 0.26; 0.21 % BOLD Signal change
N/A N=21 Benefits of Applying Neuroprosthesis to Improve Grasping and Reaching in Spinal Cord Injury Patients
Spinal Cord Injuries
Primary: Functional Independence Measure (FIM) — 20.1; 10 units on a scale — p=.015
N/A N=34 Use of Neuromuscular Electrostimulation (NMES) for Treatment or Prevention of ICU-Associated Weakness
Intensive Care Unit · Muscle Weakness
Primary: Lower Extremity Strength, at Hospital Discharge, of 3 Bilateral Muscle Groups (Pretibial, Triceps Surae, and Quadriceps) Measured Via MMT Using a Composite Medical…
Phase 2 N=66 Early Neuromuscular Electrical Stimulation For Quadriceps Muscle Activation Deficits Following Total Knee Replacement
Osteoarthritis
Primary: Change From Baseline in Isometric Quadriceps Muscle Torque 3.5 Weeks Post-operatively — -0.40; -0.67 change in N-m/kg — p=<0.001
N/A N=44 Strength, Pain and Function in Operation Iraqi Freedom/Operation Enduring Freedom Amputees: A Nurse-Managed Program
Traumatic Amputation
Primary: Lower Extremity Muscle Strength- Extension — 24.5; 26.4; 27.6; 34.1 Kilograms — p=<0.05
N/A N=76 Neural Basis of Sensory and Motor Learning: Functional Connections
Basic Science
Primary: Resting-state PMv-M1 Functional Connectivity (Fisher Z-transformed Correlation) — 0.64 unitless (Fisher z-score)
Phase 3 N=83 Neuromuscular Electrical Stimulation in Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease
Primary: Exercise Capacity — 465.5; 462.7 meters — p=<0.05
N/A N=66 Neuromuscular Electrical Stimulation (NMES) for Improving Outcomes Following Total Knee Arthroplasty (TKA)
Arthropathy of Knee Joint
Primary: Quadriceps Femoris Muscle (QFM) Strength (Dynamometer Quad Strength Lbs) — 3.35; 15.95; -5.48 lbs
Phase 2 N=25 Prevention of Skeletal Muscle Adaptations to Traumatic Knee Injury and Surgery
Anterior Cruciate Ligament Reconstruction
Primary: Cross-sectional Area of Skeletal Muscle Fibers (All Fibers) — 2827; 3318; 2206; 2376 micrometer squared — p=<0.05
N/A N=20 NMES Efficacy on Patients With NBPP
Neonatal Brachial Plexus Palsy
Primary: Change From Baseline in Upper Extremity Muscle Strength — 1; 1 score on a scale — p=0.40
N/A N=9 Neurosciences-Intensive Care Unit Electrical Stimulation
Intensive Care (ICU) Myopathy
Primary: Duration of Intubation — 10.22 days
N/A N=21 Neuromuscular Electrical Stimulation (NMES) in Patients With Intermittent Claudication
Intermittent Claudication · Peripheral Vascular Disease
Primary: Change From Baseline in Initial Walking Distance — 64.3 metres
N/A N=30 Muscle Fatigue and Scapular Sensorimotor System
Muscle; Fatigue
Primary: Change From Baseline in Scapular Proprioception — -0.48; -0.19; -0.37; -0.32 centimeters — p=0.227
Phase 4 N=116 Does Deep Neuromuscular Blockade Improve Operating Conditions During Total Hip Replacements?
Arthropathy of Hip
Primary: Surgical Conditions — 1; 2; 11; 10 Participants
N/A N=50 Transmembrane Electromyography (TM-EMG) for the Assessment of Neuromuscular Function in the Oropharynx
Obstructive Sleep Apnea · Amyotrophic Lateral Sclerosis · Muscular Dystrophies
Primary: Proof of Diagnostic Consistency — 95.7; 78.1; 90 % agreement
Early Phase 1 N=32 Premature Fatigue in Veterans With Heart Failure: Neuronal Influences
Heart Failure
Primary: Maximal Voluntary Quadriceps Force [% Change From Baseline] — -30; -5 percentage change
N/A N=35 Mitochondrial Function in Circulating Cells and Muscle Tissue
Healthy · Obesity · Insulin Sensitivity
Primary: Mitochondrial Function in Circulating Cells and Muscle Tissue in Young Women — 26.48; 30.46; 120.04; 140.43 pmol O2/min per 400K cells
N/A N=22 Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors
Breast Cancer
Primary: Maximal Calcium-activated Tension Single Muscle Fiber Tension — 185; 172; 172; 168 milliNewtons per millimeter^2
N/A N=33 Novel Intervention to Influence Muscle Plasticity in Veterans
Spinal Cord Injuries
Primary: HF Muscle Force — 23.9; 30.9 Newtons (N)
N/A N=42 Improving Motor Function After Spinal Cord Injury
Spinal Cord Injury
Primary: Physiology Measurements Before and After rTMS/Sham rTMS Protocol- Changes in Amplitude of Motor Evoked Potential (MEP) From TMS — 0.31; 0.43; 0.45; 0.65 millivolts (mV)
N/A N=9 Neural Prostheses and Gait Performance: Model-Based Strategies
Hemiplegia
Primary: Walking Stability and Speed — 0.1055; 0.0390; 0.0206 Joules/body mass in kilograms
Phase 1 N=23 Spinal Excitation to Enhance Mobility
Aging
Primary: Walking Speed Change From Baseline — .054; .078; .085; .039 meters/second
N/A N=16 Functional Change With MMS
Muscle Weakness
Primary: Change in Body Satisfaction Questionnaire From Baseline to 1-month Post-Treatment Follow-up Visit — 8.6 units on a scale
N/A N=5 Neural Adaptation After Tendon Transfer and Training in Tetraplegia
Spinal Cord Injury
Primary: Pinch Force — 8.7; 10.6 newtons
N/A N=60 Electromyographic and Acceleromyographic Monitoring in Restricted Arm Movement Surgical Setting
Residual Neuromuscular Blockade
Primary: Accuracy of Values Between Tetragraph and ToFscan — 0; 2 Participants
N/A N=122 Functional Electrical Stimulation (FES) for Upper Extremity Recovery in Stroke
Stroke, Acute · Stroke · Hemiparesis
Primary: Fugl-Meyer Motor Assessment (FMA) - Motor Impairment Measure — 27.5; 29.8; 26.8; 31.8 units on a scale — p=0.18
N/A N=30 Stabilization Exercises Alone vs Stabilization Exercises Plus Neuromuscular Electrical Stimulation in People With Chronic Low Back Pain
Low Back Pain
Primary: Tolerability of Electrical Stimulation (NMES) — 0; 5; 8; 0 Participants