Clinical Trial Search

Primary: Change From Baseline to Week 4 in the Weekly Average of the Daily Pain Score as Derived From the Subject's Responses on the Pain Intensity Numerical Rating Scale…

Primary: Visual Analogue Scale Score Referring to Radicular Pain (VAS-rad) — 58.7; 67.7; 13.6; 59.7 units on a scale

Primary: Pain Scores (NRS) at 3-weeks — 6; 3 units on a scale — p=0.279

Primary: Mean Change From Baseline (Day 1) to Week 4 in the Mean Numeric Pain Rating Scale (NPRS) Average Pain Score in the Affected Leg — -2.34; -1.16 Change in score on a scale…

Primary: Numerical Rating Leg Pain Score — 2.54; 3.56; 3.78 units on a scale

Primary: Visual Analog Scale — 5.638; 5.050; 5.094; 4.894 Centimeters

Primary: Average Leg Pain at 1 Month Measured Using the Numeric Pain Scale — 3.3; 3.7 units on a scale

Primary: Pain Assessed by Visual Analogue Scale — 5.63; 5.92 units on a scale

Primary: Time to First Symptoms of Moderate Pain — 2.52; 3.06 minutes

Primary: Change From Baseline in Pain Related Sleep Interference Scale (PRSIS - Past Week Recall) — 3.1; 2.9; -1.306; -0.357 scores on a scale — p=<0.001

Primary: Percentage of Participants With ≥50% Pain Reduction on the Numeric Rating Score (NRS) for Pain — 60; 72 percentage of participants — p=0.23

Primary: Clinical Pain Severity - 50% Reduction Responders vs Nonresponders — -83; 0 percentage of change

Primary: Numeric Pain Rating Score — 7.9; 8.1; 4.9; 3.4 units on a scale — p=<0.001

Primary: Recruitment Rate — 32 Participants

Primary: Change in Spontaneous Pain at 60-120 Minutes After Lidocaine Infusion Initiated (Assessed on 0-10 NRS) — 33; 51 percentage of pain change from baseline — p=0.03

Primary: The Change in Modified Roland-Morris Disability Questionnaire (RMDQ) Score From Baseline — -4.3; -3.0 score on a scale

Primary: Pre-epidural Warm Sensation Quantitative Sensory Testing (QST) Results — 2.68; 5.67 Degrees Celsius — p=.04

Primary: Effect Size of VAS Pain — 24.8; 31.3 units on a scale

Primary: Neuropathic Pain in Subjects With Peripheral Neuropathic Pain Conditions During the Double-blind Phase — 2.84; 3.62 score on scale — p=0.0018

Primary: Change From Baseline to End of Treatment (EOT) in Weekly Mean Pain Score on the Daily Pain Rating Scale (DPRS) — -3.8 scores on scale — p=< 0.0001

Primary: The Number of Participants With Adverse Events by Dose (Part A) — 1; 1; 2; 2 participants

Primary: Primary Composite Endpoint - Treatment Success — 81.2; 55.7 percentage of subjects — p=<0.0001

Primary: Percentage of Patients With Magnetic Resonance Imaging (MRI) Evidence of Tissue Ablation/Edema at Targeted Lumbar Medial Branches — 100 percentage of participants

Primary: Roland Morris — 11.8; 12.5 units on a scale

Primary: Change From Baseline of Surgical Site Pain Level (NRS) at Rest [Percentage of Baseline Pain] — 64; 100; 55; 69 percentage of baseline

Primary: Pain Assessment — 6.5; 1.0 score on a scale

Primary: Tolerability of Electrical Stimulation (NMES) — 0; 5; 8; 0 Participants

Primary: Change in Pain Numerical Rating Scale (Averaged Over Past 24 Hours) — -3.38; -2.30 score on a scale — p=0.057

Primary: Numeric Pain Rating Scale (NPRS) — 14; 3 Participants

Primary: Number of Subjects That Experienced ≥30% Reduction in Average Low Back Pain Intensity — 58 Participants