N/A N=164 Extracardiac Complications After Cardiac Surgery
Acute Lung Injury · Sepsis · Infections
Primary: Acute Lung Injury After Cardiac Surgery — 20 participants — p=<0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=336 Assessment of Myocardial Ischemic-Reperfusion Injury During Off- and On- Pump CABG
Ischemic Heart Disease · Coronary Artery Disease · Ischemic Reperfusion Injury
Primary: Myeloperoxidase — 184.3; 66.5; 144.71 g/L
N/A N=200 Cerebral Oximetry and Neurocognitive Functions in Cardiosurgical Patients
Coronary Artery Disease · Postoperative Cognitive Dysfunction · Neurological Impairment
Primary: Difference in Incidence of Cognitive Impairment Between Groups. Change Between Preoperative and Postoperative Cognitive Function Was Assessed by Performing Standardized…
Phase 4 N=798 Ancillary Effects of Dexmedetomidine Sedation After Cardiac Surgery
Heart Disease
Primary: Number of Patients With Atrial Arrhythmia — 121; 134 Participants — p=0.34
N/A N=460 Cerebral Autoregulation Monitoring During Cardiac Surgery
Thoracic Surgery · Cardiopulmonary Bypass
Primary: Composite Neurological Outcome of Clinical Stroke or New Ischemic Brain Lesion on Diffusion Weighted MRI or Neurocognitive Dysfunction 4 to 6 Weeks After Surgery. — 79…
N/A N=234 Dysrhythmias During General Anesthesia in Children
Arrhythmias, Cardiac
Primary: Arrhythmias During General Anesthesia in Children — 220 participants
N/A N=677 Unexpected Cardiac Arrest in Intensive Care Unit
Heart Arrest
Primary: Number of Patients With Unexpected Cardiac Arrest — 677; 30,722 Participants
N/A N=142 Evaluation of Microcirculatory Function and Mitochondrial Respiration After Cardiovascular Surgery
Shock · Cardiovascular Diseases · Critical Illness
Primary: Perfused Vessel Denisty (PVD) — 22.8; 23.8; 20.2; 22.5 mm/mm^2
Phase 3 N=201 Risk of Oxygen During Cardiac Surgery Trial
Cardiac Surgery
Primary: Intraoperative Systemic Oxidative Damage — 69; 83 pg/ml
Phase 2 N=51 Measures to Lower the Stress Response in Pediatric Cardiac Surgery
Tetralogy of Fallot (TOF) · Ventricular Septal Defects (VSD) · Atrioventricular Septal Defects (AVSD)
Primary: ACTH and Cytokine Levels — 116.9; 182.7; 135.3; 44.5 pg/mL
N/A N=80 Nitroglycerin Infusion During Cardiac Surgery
Lactic Acidosis · Blood Glucose, High
Primary: Plasma Lactate Level, Before Incision — 1.1; 1.0 mmol/L — p=0.618
N/A N=10 On-pump Intraoperative Echocardiography
Septal Myectomy
Primary: Septal Thickness Measured Before Cardiopulmonary Bypass — 22.9; 22.5 millimeters
N/A N=60 Ninvasive Cardiac Output Measurements During Cesarean Delivery Under Spinal Anesthesia.
Hypotension During Cesarean Delivery · Spinal Anesthesia
Primary: Percentage of Participants With a Cardiac Output Within and Outside 20% of Baseline Values — 71; 66; 29; 34 percentage of patients — p=0.37
N/A N=40 Intraoperative Echocardiography in Low-Risk CABG Surgery
Heart Diseases · Coronary Artery Disease · Chest Pain
Primary: Enrollment and Randomization Feasibility — 40 Participants
N/A N=48 Temperature Monitoring in Cardiac Surgery: Agreement Between Different Clinical Methods
Temperature Change, Body
Primary: Agreement Between Different Core Temperature Methods — 35.0; 35.2; 35.6; 34.8 celsius degrees (mean difference)
Phase 4 N=314 Effects of Microplegia on Transfusion Rates After Cardiac Surgery
Aortic Valve Disease · Mitral Valve Disease
Primary: Intraoperative and Postoperative Transfusions — 2.43; 2.97; 4.42; 3.50 units of blood per participant — p=0.354
Phase 3 N=882 Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass
Coronary Artery Bypass Grafting · Mitral Valve Surgery · Low Cardiac Output Syndrome
Primary: Number of Dual Efficacy Endpoint Events — 56; 48 events
N/A N=180 GDT by Cardiac Index Trending Via a Radial Arterial Line in General Surgery
Reduction of Length of Hospitality Stay, Reduction of Perioperative Complications
Primary: Postoperative Complications — 52; 72 numbers of complications
N/A N=29 Proteolytic Enzyme Induction Within the Human Myocardial Interstitium
Heart Disease
Primary: Pulmonary Vascular Resistance — 153.8; 213.0; 174.6; 123.5 dyne*second/centimeter˄5 — p=<0.05
Phase 4 N=100 The Effect of Dexmedetomidine Infusion on Post-operative Cognitive Function and Oxidative Stress in Cardiac Surgery
Oxidative Stress · Cognition Disorders
Primary: Numbers of Participants With Postoperative Cognitive Dysfunction (POCD) — 12; 8 Participants — p=0.289
Phase 1 N=6 Utilization of Confocal Microscopy During Cardiac Surgery
Atrial Septal Defect
Primary: Number of Participants Who Experienced Adverse Events Possibly Related to Study Intervention — 0; 6 Participants
Phase 2 N=448 Myocardial Protection With Multiport Antegrade Cold Blood Cardioplegia
Coronary Artery Bypass Surgery
Primary: Post-op CK-MB Levels — 71.70; 92.66 IU/L — p=<0.05
Phase 4 N=55 Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy
Esophageal Diseases · Gastrointestinal Diseases · Disorder of the Genitourinary System
Primary: Length of Hospital Stay (LOS) by Participant
N/A N=10 Blood Volume and Fluid Kinetics in Patients Undergoing Extracorporal Circulation
Blood Volume, Extravasation
Primary: Blood Volume — 4.61 Litre
Phase 4 N=50 Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method
Arrhythmia, Cardiac · Kidney Cancer · Surgery
Primary: Incidence of Perioperative Cardiac Arrhythmias Evaluated by a Continuous ECG Holter Monitoring in the Perioperative Period — 6; 6; 18; 16 Participants — p=0.3861
N/A N=40 Effect of Prewarming on Microcirculatory Response
Coronary Artery Bypass Graft Triple Vessel
Primary: Recovery Slope — 2.8; 3.1 % / sec (recovery slope unit)
N/A N=10 Microembolic Signals and Cerebrospinal Fluid Markers of Neuronal Damage After Surgical Aortic Valve Replacement
Aortic Stenosis
Primary: Transcranial Doppler(TCD) Microembolic Signals During Surgical Aortic Valve Replacement Surgery — 354 units on a scale
N/A N=46 Arterial Pulse Waveform Contour Analysis for Intraoperative Goal Directed Therapy in Major Abdominal Surgery
Surgical Procedures, Operative
Primary: Length of Postoperative Hospital Stay — 7.5; 5.0 Days
N/A N=200 Clinical Evaluation of the CM-1500 in Postoperative Surgery Patients
Blood Loss
Primary: Relative Index Change During PACU Stay — -2.01; -1.32 Relative Index (RI)
N/A N=100 Delirium and EuroSCORE II in Cardiac Surgery
Delirium
Primary: Number of Participants With Delirium — 5 Participants