Phase 4 N=102 Study of Exparel Versus Epidural for Pain Control After Thoracotomy
Pain Following Thoracotomy Surgery
Primary: Pain Scores With Cough on First Postoperative Day — 6.1; 6.9 units on a scale — p=0.142
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=176 Video-assisted Thoracoscopic Surgery - Exparel Study
Pain, Postoperative
Primary: Number of Subjects With Post-operative Opioid Usage — 42; 58 Participants
N/A N=80 Lidocaine 5% Patch (Lidoderm) for the Prevention of Acute and Chest Pain Following Robotic Valve Surgery
Perioperative Chest Pain
Primary: Pain Disability Index Score (PDI) at Six Months Following Surgical Procedure — 26; 30; 12; 13 units on a scale — p=0.28
N/A N=146 Preoperative Gabapentin for Acute and Chronic Post-thoracotomy Analgesia
Pain
Primary: Average Pain Score at Rest — 3.1; 2.9 Units on a scale
Phase 4 N=65 Assessment of Intercostal Block Scheduling in Preventing Acute Surgical and Post-surgical Pain in Thoracoscopic Surgery
Chest Pain · Surgery
Primary: Analgesic Use — 33.35; 35.32 MG
Phase 4 N=52 Efficacy of Patient Controlled Epidural Anesthesia Versus Continuous Epidural Analgesia for Post-thoracotomy Pain
Acute Post-thoracotomy Pain
Primary: Local Anesthetic Consumption — 1505.39; 1862.16 ug
Phase 2 N=90 Analgesic Efficacy of Inter Pleural Ropivacaine Road in Post Thoracotomy Pain for Oncologic Surgery
Postoperative Pain · Cancer
Primary: Proportion of Patients With Major Post-operative Pain at Mobilization Following Lung Surgery by Posterolateral Thoracotomy — 4; 3 Participants — p=0.99
Phase 3 N=57 Exparel and Marcaine for Pain Management in Thoracoscopic Lobectomy Patients
Non Small Cell Lung Cancer · Lung Cancer Stage 1
Primary: Total Morphine Equivalents Consumed — 48; 42.7 MEq
Phase 4 N=60 The Use of Paravertebral Block for Cardiac Surgery
Mitral Valve Insufficiency
Primary: Postoperative Fentanyl — 4.51; 6.14 microgram/kilogram
Phase 4 N=15 Pregabalin and Post-thoracotomy Pain
Chronic Pain
Primary: The Primary Outcome Measure for the Final Study Will be the Incidence of CPTPS at 2 Months.
N/A N=85 Post Operative Pain Control Using Ropivacaine and the ON-Q System in the Adult Pectus Excavatum Patient
Pectus Excavatum
Primary: Hospital Length of Stay — 3.5; 3.3 days — p=0.55
N/A N=36 The Impacts of Pulmonary Rehabilitation Therapy on Patients After Thoracic Surgery
Lung Neoplasms
Primary: Discharge 2weeks Exercise Capacity — 408.61; 311.94 meter(M) — p=<0.05
N/A N=129 Reducing Pain and Disability After Breast Cancer Surgery
Breast Cancer · Chronic Pain
Primary: The Proportion of Individuals Reporting Chronic Postoperative Pain 12 Months Following Breast Cancer Surgery With Lymph Node Dissection. — 5; 4 Participants
Phase 4 N=20 Intercostal Nerve Cryoablation for Postoperative Pain Management
Pain, Postoperative
Primary: Score on Numeric Pain Scale (NPS) — 1.5; 3 score on a scale
N/A N=83 Continuous Subpleural Infusion of Bupivacaine
Postoperative Pain
Primary: Number of Participants With and Without 30-Day Pain Medication Usage — 8; 6; 30; 36 participants
Phase 3 N=161 Postoperative Thoracic Epidural Analgesia Versus Intravenous Patient-Controlled Analgesia For Liver and/or Pancreas
Liver Cancer · Pancreatic Cancer
Primary: Postoperative Pain Experience — 78.6; 105.2 score on a scale* hour
Phase 2 N=38 Dexmedetomidine for the Control of Post-Operative Pain in Thoracotomy Patients
Post-operative Pain · Respiratory Depression
Primary: Measure Any Reduction in the Amount of Opioid Administered to Patients in the Dexmedetomidine Study Arm. — 49; 29; 54; 35 IV morphine equivalency in mg — p=0.03
N/A N=42 Evaluating Transcutaneous Electrical Nerve Stimulation for Postoperative Pain After Video-Assisted Thoracotomy Surgery
Postoperative Pain
Primary: Mean Pain Score — 4.55; 3.85; 4.30; 3.80 units on a scale
Phase 4 N=16 Analgesic Efficacy of Intravenous Acetaminophen After Video-assisted Thoracic Surgery
Lung Tumor
Primary: Total Morphine Consumption (mg) — 34.5; 44 mg
N/A N=110 Pain Management for Pectus Excavatum Repair
Postoperative Pain
Primary: Length of Hospitalization — 4.54; 4.25 days
N/A N=10 Feasibility Study for Intrathoracic Nerve Stimulation
Postoperative Pain
Primary: Pain as Measured by the Visual-analog Scale — 1 units on a scale
Phase 3 N=147 Comparison of Three Different Pain Blocks for Subjects Undergoing VATS (Video Assisted Thoracoscopic Surgery) Procedure.
Video Assisted Thoracoscopic Surgery · Pain, Postoperative · Pain, Acute
Primary: The Primary Endpoint of This Study Will be VAS Pain Score at 24 Hours — 4.0; 4.5; 3.0 units on a scale
Phase 4 N=36 Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures
Drug Effect · Rib Fractures · Rib Trauma
Primary: Daily Sequential Clinical Assessment of Respiratory Function (SCARF) Score — 2; 2 score on a scale — p=0.12
Phase 4 N=31 Pecto-intercostal Fascial Block (PIFB) for Postop Analgesia Following Sternotomy in Cardiac Surgery Patients
Analgesia · Sternotomy
Primary: Area Under the Curve (AUC) Pain Score - Based on Patient-reported Dynamic Numerical Rating Scale (NRS) Pain Scores — 6.39; 4.22 scores on a scale*hour
Phase 3 N=331 Placebo Controlled Clinical Trial of the Postoperative Opioid Sparing Effects of Intraoperative Dexmedetomidine Infusion for Thoracic Surgery
Pain
Primary: Total Opioid Administered — 4.0; 6.0 Morphine Milligram Equivalents
N/A N=80 Comparison of the Effect of Preoperative and Postoperative ESP and PVB on Postoperative Pain in VATS
Anesthesia · Nerve Block · Pain, Postoperative
Primary: Acute Postoperative Pain (With NRS ) — 3.5; 3; 4; 4 NRS score — p=0.365
N/A N=113 Improving Quality of Life After Thoracic Surgery Using Patient-Reported Outcomes
Thoracic Surgery
Primary: Quality of Life at 12 Months — 80.97; 84.02 units on a scale
Phase 4 N=41 Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled Trial
Rib Fractures · Pain, Acute
Primary: Evaluation of Pain — 4; 4 score on a scale
Phase 3 N=191 Intercostal Nerve Block With Liposome Bupivacaine in Subjects Undergoing Posterolateral Thoracotomy
Posterolateral Thoracotomy · Postoperative Pain
Primary: Area Under the Curve (AUC) of Pain Intensity at Rest Through 72 Hours — 472.1; 459.0 score on a scale * hr — p=0.5598
N/A N=65 Thoracic Paravertebral Block Using Ropivacaine and Dexmedetomidine
Pain, Postoperative
Primary: Postoperative Pain (Pain Scores) Intensity Measure — 1; 3 units on a scale — p=0.001