30 closest matches · ranked by relevance
Panic Disorder
Primary: Mean Change From Baseline in Panic and Agoraphobia Scale (PAS) Total Score at the End of Treatment Phase — -17.4; -17.0 Scores on scale
Panic Disorder
Primary: Change in Panic Disorder Symptoms, Phase 1 (Week 0 - Week 6) — 4.3 Points on a scale — p=0.0000
Panic Disorder
Primary: Panic Disorder Severity Scale (PDSS) — 13.30; 13.37; 7.98; 8.32 units on a scale
Panic Disorder
Primary: Incidence of Treatment-Emergent Adverse Events — 23; 15 Participants
Panic Disorder
Primary: Panic Disorder Severity Scale (PDSS) — 9.13 units on a scale
Treatment of Induced Panic Attack
Primary: Number of Participants With Doxapram-induced Panic Attack — 14; 9 Participants — p=0.200
Panic Disorder · Major Depressive Disorder
Primary: Panic Disorder Severity Scale (PDSS) — 6; 1 responders
Anxiety Disorders · Panic Disorder · Agoraphobia
Primary: Panic Disorder Severity Scale — 6.72; 5.78; 7 score on a scale — p=>0.16
Panic Disorder
Primary: Participants´Endpoint Change From Baseline in Hamilton Anxiety Rating Scale — 22.59; 22.73 Units on a scale — p=<0.001
Post-traumatic Stress Disorder · Generalized Anxiety Disorder · Panic Disorder
Primary: BSI-12 (Anxiety and Somatization Subscales) — 325; 258 number of responders
Bipolar Disorder · Panic Disorder · Generalized Anxiety Disorder
Primary: Clinician Global Improvement Scale (CGI-21) — 7.8; 3.4 units on a scale
Panic Disorder
Primary: Percent of Subjects Achieving a 40% Decrease in Overall PDSS Score (Clinically Significant Response) — 33 Participants
Healthy
Primary: Maximum Change From Baseline in Panic Symptom Scale (PSS) Sum Intensity Score — 22.639; 29.944 Score on a scale
Generalized Anxiety Disorder · Panic Disorder
Primary: Cumulative Percent of Participants Showing a Response in the Symptoms of Anxiety (Decrease in Total Hamilton Anxiety (HAM-A) -Score of >=50%) in the Intent-to-treat…
Panic Disorder
Primary: Number of Participants of Treatment Related Adverse Events (TRAEs) — 110 participants
Panic Disorder
Primary: Change in Orexin Levels (Blood) +1 Minute
Anxiety Disorders
Primary: Change in Percent of Correct Button Presses During Threat Compared to the Safe Condition (AAST) — -0.016; 0.008 Percentage of accurate responses
Adjustment Disorder With Anxious Mood
Primary: Hamilton Anxiety Scale (HAM-A) Score — -12.5; -12.6 score on a scale — p=0.9338
Generalized Anxiety Disorder (GAD) · Anxiety, Separation · Phobia, Social
Primary: Change From Baseline in Systolic Blood Pressure at Up to 12 Weeks — -1.7; -2.3 mmHg
Panic Disorder
Primary: Change in Mean Total Panic Disorder Severity Scale (PDSS) Scores — -5.3; -5.6 units on a scale
Generalized Anxiety Disorder (GAD)
Primary: Change From Baseline in Hamilton Anxiety Rating Scale (HAM-A) Total Score at Visit 7 (Day 42) — -9.01; -8.93 Score on scale
Nicotine Addiction · Panic Attack
Primary: Smoking Abstinence — 8.25; 12.35 percentage of participants
Social Anxiety Disorder · Social Phobia · Alcohol Use Disorder
Primary: Social Anxiety Severity — 87; 93 units on a scale
Social Anxiety Disorder
Primary: Liebowitz Social Anxiety Scale (LSAS) — 7.77; 7.84 units on a scale — p=.267
Panic Disorder
Primary: Change From Baseline Score in the Panic Disorder Severity Scale at 8 Weeks and 6 Months. — 15.29; 15.75; 13.08; 10.42 units on a scale (range= 0-28) — p=0.05
Stress Disorders, Post-Traumatic
Primary: Change in Clinician Administered PTSD Scale (CAPS) Scores — -3.40; -5.00 Units on a scale — p=0.7054
Separation Anxiety Disorder
Primary: Clinical Global Impression-Improvement Scale — 7; 4 Participants — p=.064
Social Anxiety Disorder
Primary: Subjective Units of Distress Scale (SUDS) Score — 77.7; 78.2; 62.3; 61.3 score on a scale — p=.5063
Anxiety Disorder
Primary: Change in HAM-A Total Score — -12.9; -15.7; -12.5 Units on a Scale — p=0.6540
Generalized Anxiety Disorder
Primary: Change From Baseline in the Hamilton Rating Scale for Anxiety (HAM-A) Total Score — 14.7; 11.3 Score on Scale — p=0.0048