Phase 4 N=60 The Use of Paravertebral Block for Cardiac Surgery
Mitral Valve Insufficiency
Primary: Postoperative Fentanyl — 4.51; 6.14 microgram/kilogram
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=84 Bilateral Paravertebral Blockade (T7-10) vs. Incisional Local Anesthetic Administration for Pediatric Patients
Pain, Postoperative
Primary: Opioids Consumption Via PCA — 107.29; 100.17 ng/kg/min
Phase 4 N=100 Erector Spinae Versus Paravertebral Nerve Blocks for Breast Surgery
Breast Surgery
Primary: Numeric Rating Scale Pain Scores — 3.0; 0 score on a scale — p=0.0011
N/A N=80 Paravertebral Block for Proximal Humeral Fracture Surgery
Proximal Humeral Fracture
Primary: Success Rate(Ability to Proceed With Surgery Without the Need for Intravenous Narcotics, General Anaesthesia, Rescue Blocks or Local Infiltration by the Surgeon) — 31…
Phase 4 N=100 Serratus Plane Versus Paravertebral Nerve Blocks for Breast Surgery
Breast Surgery
Primary: Mean/Median Numeric Rating Scale Pain Score Within the Recovery Room — 4; 0 score on a scale — p=0.001
Phase 4 N=119 Pectoralis Block vs Paravertebral Nerve Blocks for Breast Surgery
Breast Surgery
Primary: Recovery Room Numeric Rating Scale Pain Scores — 3.3; 1.3 score on a scale
Phase 4 N=33 Erector Spinae Plane vs. Paravertebral Nerve Block for Thoracic Surgery
Thoracic Surgical Procedures
Primary: Total Opioid Consumption — 187.36; 164.70 mg morphine equivalent (MME)
N/A N=16 Thermal-Imaging Comparison of Nerve Blocks for Bilateral Mastectomy
Anesthesia, Conduction
Primary: Skin Temperature Increase From Baseline — 1.9; 2.3 degrees C
N/A N=65 Thoracic Paravertebral Block Using Ropivacaine and Dexmedetomidine
Pain, Postoperative
Primary: Postoperative Pain (Pain Scores) Intensity Measure — 1; 3 units on a scale — p=0.001
Phase 2 N=70 Intravenous(IV) vs. Erector Spinae Plane Blocks in Cardiac Surgery
Erector Spinae Plane Block · Pain Control · Post-Operative Pain, Chronic
Primary: Quantitate the Amount of Opioid Medication Required to Provide Pain Relief-Cumulative First 48 Hours — 80.2; 54.9 Morphine Milligram Equivalents
N/A N=42 Ultrasound-Assisted Paravertebral Block v. Traditional Paravertebral Block For Pain Control
Paravertebral Peripheral Nerve Block · Acute Pain Management
Primary: Opioid Consumption at 24 Hours Postoperatively — 5.75; 6.38 mg — p=0.643
N/A N=48 Comparative Study of Nonintubated Uniport Thoracoscopic Surgery Using Thoracic Paravertebral Nerve Block Versus Intercostal Nerve Block for Peripheral Solitary Pulmonary Nodule Patients
Peripheral Solitary Pulmonary Nodule or Tuberculoma
Primary: Comparing the Inflammatory Markers During the Operation After the Intervention of the Each Group — 33; 35; 39; 42 pg/L — p=0.025
N/A N=129 Reducing Pain and Disability After Breast Cancer Surgery
Breast Cancer · Chronic Pain
Primary: The Proportion of Individuals Reporting Chronic Postoperative Pain 12 Months Following Breast Cancer Surgery With Lymph Node Dissection. — 5; 4 Participants
Phase 4 N=44 Surgeon Infiltration QL Block Comparison
Quadratus Lumborum Block · Surgical Wound Infiltration
Primary: Opioid Consumption in Oral Morphine Milliequivalents for the First 24 Hours After Surgery (Defined as 24 Hours After the Anesthesia End Time) — 17.50; 21.25 oral…
Phase 4 N=85 Perineural Steroids for Peripheral Nerve Blocks
Osteoarthritis, Knee
Primary: Duration of Sensory Nerve Block — 37.00; 31.75; 29.67 hours
Phase 2 N=192 Periarticular Injection Versus Peripheral Nerve Block in Total Hip Arthroplasty
Hip Arthropathy
Primary: Daily Opioid Consumption — 29.3; 30.8; 49.6; 51.8 milligram — p=0.69
N/A N=40 Ultrasound-Guided Intercostal Nerve Block for Postoperative Pain Relief in Percutaneous Nephrolitotomy
Nerve Block, Intercostal Nerve
Primary: Postoperative Analgesic (Tramadol) Consumption
Phase 3 N=88 Evaluate the Use of Paravertebral Block in Reconstructive Breast Surgery
Breast Cancer
Primary: Proportion of Participants With No Pain Immediately After Surgery
N/A N=93 Transversus Abdominis Plane Block Versus Erector Spinae Plane Block
Postoperative Pain · Laparotomy
Primary: Time of First Post Operative Analgesic Request — 14.9; 6.5; 2.8 Hour
Phase 3 N=120 Erector Spinae Block Versus Surgeon Infiltration in VATS Procedures
Pain, Postoperative · Thoracic · Acute Pain
Primary: The Primary Endpoint of This Study Will be 24 Hours VAS Pain Score at Rest — 4.1; 4.3; 3.3 score on a scale
Phase 4 N=4 Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population
Anesthesia, Local
Primary: Ropivacaine Concentrations — 0; 0; 1232.25; 850.25 ng/mL
N/A N=30 The Effect of Interscalene Peripheral Nerve Block With 0.25% Bupivacaine vs 0.125% Bupivacaine on Lung Function
Diaphragm Paralysis
Primary: Abnormal Lung Function — 11; 3 participants w/ abnormal diaphragm fxn
Phase 4 N=93 Parasternal Nerve Block Using Bupivacaine for Postoperative Analgesia in Children Undergoing Cardiac Surgery
Pain
Primary: Total Fentanyl/Equivalent Day 0-1 — 23.6; 22.4 mcg/kg/day
Phase 4 N=102 Study of Exparel Versus Epidural for Pain Control After Thoracotomy
Pain Following Thoracotomy Surgery
Primary: Pain Scores With Cough on First Postoperative Day — 6.1; 6.9 units on a scale — p=0.142
Phase 4 N=30 Peripheral Nerve Blocks for Above-the-knee Amputations
Peripheral Vascular Diseases · Hyperglycaemia (Diabetic) · Hypertension
Primary: Peripheral Nerve Block Success as a Primary Anesthetic — 1 Participants
Phase 3 N=103 Ultrasound Guided Supraclavicular Nerve Block
Local Anesthetic
Primary: Duration of Analgesia. — 7.5; 10 minute — p=0.14
N/A N=80 Comparison of the Effect of Preoperative and Postoperative ESP and PVB on Postoperative Pain in VATS
Anesthesia · Nerve Block · Pain, Postoperative
Primary: Acute Postoperative Pain (With NRS ) — 3.5; 3; 4; 4 NRS score — p=0.365
Phase 2 N=79 Parasternal Nerve Block in Cardiac Patients
Coronary Artery Disease · Pain, Postoperative
Primary: Median Cumulative Morphine Equivalent — 0; 2.5; 0; 5 Morphine Equivalents
N/A N=30 A Comparison of Postoperative Analgesic Nerve Block Ropivacaine Concentrations
Total Hip Arthroplasty · Postoperative Pain
Primary: Opiate Consumption Postoperatively — 8.21; 8.02 mg
Phase 4 N=165 Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)
Total Knee Arthroplasty
Primary: Maximum Pain Post-Operative Day (POD) 1 (Morning) — 3; 4; 4.5 units on a scale — p=0.144