Phase 3 N=133 Use of Epidurals Intraoperatively for Patients Undergoing Pancreas Resection
Pancreatic Cancer
Primary: Number of Incidences of Grade 3 or Greater Complications — 0; 0 Number of complications
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=284 Preoperative Biliary Drainage in Resectable Pancreatic or Periampullary Cancer
Pancreatic Carcinoma
Primary: Number of Serious Pre-operative, Operative and Post-operative Adverse Events to 120 Days Post Randomization or to 30 Days Post Surgery, Whichever Comes Last — 40; 36…
Phase 4 N=50 Effects of Preoperative Immunonutrition in Patients Undergoing Pancreaticoduodenectomy
Pancreatic Cancer · Bile Duct Cancer
Primary: Postoperative Infectious Complication — 7; 15 participants — p=<0.05
N/A N=77 Accelerated Recovery Pathway for Discharge After Surgery in Patients With Pancreatic Cancer
Pancreatic Carcinoma
Primary: Percentage of Patients Discharged by Post-operative Day 5 — 5; 28 Participants
N/A N=138 Surgical Stress Markers for Postoperative Complications: a Prospective Study
Operative Procedures, Complications
Primary: Predictive Value of Postoperative Albumin Decrease in Terms of Surgical Stress and Postoperative Complications — 11.3 g/L
N/A N=399 Pancreas Resection With and Without Drains
Pancreas Tumor · Pancreatitis
Primary: 60-day ≥ Grade II Complication Rate — 72; 76 Participants — p=0.804
Phase 3 N=161 Postoperative Thoracic Epidural Analgesia Versus Intravenous Patient-Controlled Analgesia For Liver and/or Pancreas
Liver Cancer · Pancreatic Cancer
Primary: Postoperative Pain Experience — 78.6; 105.2 score on a scale* hour
Phase 2 N=52 Intra-operative Application of HEMOPATCH to the Pancreatic Stump to Prevent Post-operative Pancreatic Fistula Following Distal Pancreatectomy
Pancreas Cancer · Pancreas Disease · Pancreas Adenocarcinoma
Primary: Number of Participants With a Clinically Significant Post-operative Pancreatic Fistula (POPF) — 13 Participants
Phase 3 N=200 Standardization of Surgery on the Pancreatic Cancer
Pancreatic Cancer
Primary: Survival — 37; 31 participants
N/A N=211 Comparison Between Internal and External Preoperative Biliary Drainage in Periampullary Cancers
Periampullary Cancers With Obstructive Jaundice · Pancreas Head Cancer · Bile Duct Cancer
Primary: Incidence of Infectious Complications After Biliary Drainage — 11; 5 participants
N/A N=3 Preoperative Exercise in Pancreatic Cancer
Pancreatic Cancer
Primary: Change in 400-meter Walk Time — 212.7; 194.3; 204 s
Phase 2 N=30 Gemcitabine, Cisplatin, and Nab-Paclitaxel Before Surgery in Patients With High-Risk Liver Bile Duct Cancer
Resectable Cholangiocarcinoma · Stage IB Intrahepatic Cholangiocarcinoma AJCC v8 · Stage II Intrahepatic Cholangiocarcinoma AJCC v8
Primary: Number of Participants Who Completed All Preoperative and Operative Therapy — 22 Participants
Phase 2 N=10 Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers
Colon Cancer · Pancreatic Cancer · Cholangiocarcinoma
Primary: Number of Participants With Disease Recurrence At 1 Year — 2; 0 Participants
N/A N=7 Evaluation of Pancreatobiliary Disorders in Patients With Altered Gastric Anatomy
Pancreatobiliary Disease · Altered Gastric Anatomy
Primary: Papilla or Duct-enterostomy Was Reached — 10 ERCPs
Phase 2 N=114 A Phase II Trial of Lanreotide for the Prevention of Postoperative Pancreatic Fistula
Pancreatic Leak · Pancreatic Fistula · Pancreaticoduodenal; Fistula
Primary: Combined Clinically Significant Postoperative Pancreatic Fistula and Intra-abdominal Abscess — 8 Participants
N/A N=124 Comparison Between Wound Vacuum Dressing and Standard Closure to Reduce Rates of Surgical Site Infections
Surgical Site Infection · Pancreatic Neoplasms · Pancreatic Cancer
Primary: Rate of Surgical Site Infection — 6; 19 Participants — p=0.003
N/A N=190 Antibiotic Irrigation for Pancreatoduodenectomy
Surgery · Infection
Primary: The Number of Patients With Infections — 11; 10 Participants
Phase 4 N=174 Preoperative High Dose Steroids for Liver Resection- Effect on Complications in the Immediate Postoperative Period
Complication, Postoperative
Primary: Complications, Post-anesthesia Care Unit (PACU) — 51; 58 Participants — p=0.213
Phase 3 N=170 Secretin Infusion to Prevent Pancreatic Leaks Following Pancreatic Resection
Injury of Body of Pancreas
Primary: Number of Participants With Biochemical Leak/Grade B Fistula/Grade C Fistula — 25; 16; 3; 5 Participants
N/A N=359 Perioperative Palliative Care Surrounding Cancer Surgery for Patients & Their Family Members
Gastrointestinal Cancer
Primary: Patient Quality of Life Patient Quality of Life 12 Weeks After Surgery — 138.54; 136.90 score on a scale — p=.623
N/A N=20 Effect of Intermittent Pedicle Clamping on Hepatocellular Injury During Liver Surgery
Hepatocellular Injury · Blood Loss
Primary: Hepatocellular Damage Reflected by Liver Fatty-acid Binding Protein (L-FABP) Levels — 9097; 11,688 ng*h/mL
Phase 2 N=39 Gemcitabine and Oxaliplatin in Treating Patients With Pancreatic Cancer That Can Be Removed By Surgery
Pancreatic Cancer
Primary: Overall Survival at 18 Months — 63 percentage of participants
Phase 4 N=48 Perioperative Intravenous Lidocaine Infusion for Patients Undergoing Laparoscopic and Open Pancreatectomies
Pancreatectomy
Primary: Overall Pain in Postoperative Period — 1.6; 2.7 score on a scale — p=0.1459
N/A N=62 Phlebotomy to Prevent Blood Loss in Major Hepatic Resections
Liver Neoplasms · Hepatectomy
Primary: Total Intraoperative Blood Loss, by Measurement of Change in Hemoglobin Levels — 862; 872; 761; 872 mL
Phase 2 N=48 Perioperative Therapy for Resectable and Borderline-Resectable Pancreatic Adenocarcinoma With Molecular Correlates
Pancreatic Cancer · Pancreatic Adenocarcinoma · Pancreas Ductal Adenocarcinoma
Primary: R0 Resection Rates in Each Cohort as Measured by Macroscopically Complete Tumor Removal With Negative Microscopic Surgical Margins — 9; 9 participants with resectable PDAC
Phase 4 N=58 Improvement of Fluid Balance in Patients Undergoing Surgery of the Colon and Rectum
Colorectal Carcinoma
Primary: Peak Value of I-FABP — 440.8; 522.4 pg/mL
Phase 3 N=102 Surgical Site Infections After Liver Transplantation Based on Perioperative Antibiotics
Liver Transplantation · Surgical Site Infection
Primary: Number of Subjects With Development of Surgical Site Infections — 9; 13 Participants
N/A N=47 Clinical Safety and Performance of GATT-Patch in Open Liver Surgery
Hemorrhage, Surgical
Primary: Hemostasis — 38; 46 Participants
Phase 2 N=51 HIPEC for Peritoneal Carcinomatosis
Peritoneal Carcinomatosis · Colorectal Cancer · Appendiceal Cancer
Primary: Completeness of Cytoreduction
Phase 2 N=32 Pre-operative Treatment for Patients With Untreated Pancreatic Cancer
Resectable Pancreatic Cancer · Unresectable Pancreatic Cancer · Pancreatic Adenocarcinoma
Primary: CA 19-9 Normalization — 40; 13.6; 30; 50 Percentage of participants — p=0.235