N/A N=14 Vascular Dysfunction During Physical Inactivity
Aging · Vascular Endothelium · Skeletal Muscle
Primary: Brachial Artery Vascular Function — 5.1; 3.1; 4.4 percent vasodilation
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=150 Improving Function in Older Veterans With Hospital-Associated Deconditioning
Frail Elderly · Homebound Persons
Primary: Change in Self-Selected Walking Speed — 0.08; 0.08 m/s
N/A N=15 Exoskeleton Treatment of Deconditioning Due to Limited Ambulation Caused by Illness or Injury
Debility Due to Disease
Primary: Number of Participants Who Experience an Adverse Event During Time of Treatment — 5 Participants
N/A N=38 Home Telerehabilitation for Deconditioned Older Adults
Osteoarthritis
Primary: Exercise Adherence — 57.4; 32.1; 56.2; 35.1 percentage of days adhered — p=<.05
N/A N=129 Weight Loss Physical Disabilities
Physical Disability
Primary: Weight Change in kg From Baseline to 6-months — -6.23; -8.16 kg
N/A N=17 A Physical Activity Program in End-state Liver Disease
End-stage Liver Disease (ESLD) · Liver Transplant · Sarcopenia
Primary: Physical Fitness - VO2 — -1; -3 mL oxygen/kg/min — p=0.49
N/A N=65 Does Pulmonary Rehabilitation Improve Frailty?
Disease, Pulmonary
Primary: Number of Participants With Frailty Phenotype at Baseline and 6 Months — 24; 15 Participants — p=0.62
N/A N=23 Skeletal Muscle Atrophy and Dysfunction Following Total Knee Arthroplasty
Knee Osteoarthristis
Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared
N/A N=20 Preventing the Loss of Muscle and Function in Hospitalized Older Adults
Muscular Atrophy
Primary: The Percent Change in Bilateral Thigh Lean Mass Density (Grams) as Measured by DEXA Scan Will be Compared Between Baseline and After 5-days of Bed Rest — -3.845; -0.249…
N/A N=71 Musculoskeletal Plasticity After Spinal Cord Injury
Spinal Cord Injuries
Primary: Acute Gene Regulation: MSTN — 5.49; 4.76 arbitrary units — p=<0.001
N/A N=38 Strength Training for Skeletal Muscle Adaptation After Stroke
Stroke
Primary: Change in 1-repetition Maximum (RM) Muscle Strength (Leg Press, Paretic Side) — 126.1; 11.3 lbs
N/A N=37 Exercise to Prevent Muscle Mass and Functional Loss in Elderly Dialysis Patients
Chronic Kidney Disease
Primary: Maximal Oxygen Uptake — 14.5; 15.1 ml/kg/min
N/A N=40 Assessment of Body Composition and Physical Function
Body Composition · Physical Function
Primary: Fat Mass — 44.71 Kg
Phase 2 N=34 Biological Effects of Weight Loss In Older, Obese Women
Obesity · Sarcopenia
Primary: Performance on the 400 Meter Walk — 0.16; 0.02 meters per second — p=<0.05
N/A N=21 The Trajectory of Physical Activity Following Pulmonary Rehabilitation
COPD · Pulmonary Disease, Chronic Obstructive
Primary: Minutes/Day at 12 Weeks — 1.3125000 minutes/day
N/A N=135 Physical Activity in the Medical Workplace
Physical Activity
Primary: Change in Fitbit Step Count Per Day — -323.5; 321.2 steps
N/A N=33 Development of a Rehabilitation Strengthening and Mobility Program for Ventilator Dependent Older Patients
Respiration, Artificial · Critical Illness · Chronic Disease
Primary: Functional Assessment: Handgrip — 3.6; 1.3 kg
Early Phase 1 N=32 Premature Fatigue in Veterans With Heart Failure: Neuronal Influences
Heart Failure
Primary: Maximal Voluntary Quadriceps Force [% Change From Baseline] — -30; -5 percentage change
N/A N=37 Forearm Immobilization, Metabolic Health, and Muscle Loss
Healthy
Primary: Percent Change in Forearm Glucose Uptake — -73; 127; -95 Percent change in clamp FGU with immob
N/A N=45 CogXergaming to Promote Physical Activity and Cognitive Function in Frail Older Adults
Frail Older Adults
Primary: Change in 30-second Chair Stand Performance — 10.28; 12.11; 12.36; 12.30 number of repetitions
N/A N=66 Study of the Long-term Effects of Exercise on Heath Indicators in Older People
Hypertension With Complications and Secondary Hypertension · Overweight and Obesity · Lipid Metabolism Disorders
Primary: Cardiovascular Disease Risk Factors — 3; 4; 5; 7 participants
N/A N=52 Behavioral Activation-Rehabilitation to Improve Depressive Symptoms & Physical Function After Acute Respiratory Failure
Respiratory Insufficiency · Depression · Rehabilitation
Primary: Feasibility Measure Per Participant — 0.8 proportion of intended visits
N/A N=100 Exercise Intolerance in Elderly Patients With Diastolic Heart Failure
Heart Failure, Diastolic · Obesity
Primary: Exercise Capacity — 15.5; 15.5; 14.1; 16.6 ml/kg/min — p=<0.001
Phase 2 N=19 Electrical Stimulation for Critically Ill Post-Covid-19 Patients
COVID-19 · Muscle Atrophy · Muscle Weakness
Primary: Gastrocnemius Muscle Endurance (Muscle Sustained Contraction) in Response to Electrical Stimulation — 363.04; 359.55 miliVolts
N/A N=15 Home-Based Exercise to Treat Decreased Physical Function in Patients With Varying Levels of Kidney Function
Chronic Kidney Disease
Primary: Change in Short Physical Performance Battery Score — -1 units on a scale — p=0.73
N/A N=53 Benefits of Physical Exercise in Schizophrenia
Schizophrenia
Primary: VO2max — 4.0; 0.2 ml.kg-1.min-1 — p=0.02
Phase 1 N=67 Effect of Intensified Physical Activity for Patients With Stroke - a Combined Physical and Behavioural Approach
Stroke
Primary: The Berg Balance Scale (BBS) — -0.06; 4.1; 0.8; 2.3 units on a scale — p=0.001
N/A N=76 Integrated Physical Training With Protein Diet in Older Adults With Sarcopenia Symptoms.
Sarcopenia
Primary: Changes in Hand Grip Strength — 29.2; 29.5; 35.3; 30.3 kg — p=<0.05
Phase 1 N=19 Electrical Stimulation for Critically Ill Covid-19 Patients
Covid19 · Muscle Atrophy · Muscle Weakness
Primary: Change in Gastrocnemius Muscle Endurance (Muscle Sustained Contraction) in Response to Electrical Stimulation — 352; 323 milliVolts
N/A N=13 The Effects of Altering Physical Activity on Cardiometabolic Health
Insulin Resistance
Primary: Effects of Physical Inactivity on Post Prandial Blood Flow — 0 percentage of change in blood flow