N/A N=184 Clinical Performance of Two Fissure Sealants
Caries Pit and Fissure Limited to Enamel
Primary: Retention of the Sealant — 0; 0; 164; 164 Sealants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=597 Glass Ionomer Sealant and Fluoride Varnish Study to Prevent Early Childhood Caries
Dental Caries
Primary: Caries Incidence — 137; 123 Participants
N/A N=12 An Evaluation of Protective Effects of OpalSeal™ Against Early Dental Decay in Orthodontic Patients
Cavities of Teeth
Primary: Loss of Mineral Density in the Enamel — 70.8; 77.4 microns
N/A N=32 DryShield vs Cotton Roll Isolation During Sealants Placement: Efficiency and Patient Preference
Time · Patient Preference
Primary: Placement Time of Sealants Using Dryshield (DS) vs Cotton Rolls (CRI) — 164.88; 160.50; 164.56; 167.81 Seconds
N/A N=16 Prevention of Enamel Demineralization by Use of K18-smooth Surface Sealant
Dental Caries
Primary: Change in Mineral Density Determined by the Canary Caries Detection System — 23.424; 31.125; 35.563 Canary Number — p=0.0003
N/A N=896 An Implementation Strategy for the Adoption of an Evidence-Based Guideline for Pit-and-Fissure Sealants
Pit-and-Fissure Sealants
Primary: Change in Providers' Rates of Placing or Treatment Planning Sealants for Occlusal NCCLs — 137; 95 Teeth — p=0.18
N/A N=7,418 Comparative Effectiveness of School-based Caries Prevention
Dental Caries · Quality of Life
Primary: Proportion of Subjects With All Caries Arrested — 108; 101 Participants
N/A N=3,345 Comparative Effectiveness of Treatments to Prevent Dental Caries
Dental Caries
Primary: Number of Participants With Arrested Dental Caries, Assessed Using a Clinical Oral Examination — 48; 53 Participants
N/A N=208 A Clinical Trial Comparing Isolite® vs. Cotton Roll Isolation in the Placement of Dental Sealants
Dental Caries on Pit and Fissure Surface
Primary: Sealant Retention Percentage at 12 Months After Treatment — 59; 66 teeth
Phase 2 N=70 Self Assembling Peptide P11-4 in Patients With Early Occlusal Carious Lesions
Dental Caries
Primary: Caries Activity and Progression Assessment Using LASER Fluorescence Readings by Diagnodent® Device. — 18.6; 1.1 units on a scale
N/A N=120 Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser
Dental Caries
Primary: International Caries Detection and Assessment System (ICDAS II) - Number of Molars With ICDAS Score of 3 or More - ICDAS Score 3, Cavity - — 0; 13 right or left second…
N/A N=61 Clinical Evaluation of 3M™ ESPE™ Adper™ Scotchbond™ SE Self-Etch Adhesive in Class I and Class II Restorations in Adults
Dental Caries
Primary: Percentage of Restorations Scoring Alpha — 100; 96 percentage of Alpha scores — p=0.05
N/A N=51 Treatment of Interproximal Cavities on Primary Molar Teeth With Silver Diamine Fluoride
Dental Caries in Children · Dental Caries Class II · Dental Caries
Primary: Interproximal Caries Zone of Radiolucency — 9; 7; 10; 12 Number of teeth
N/A N=57 Silver Diamine Fluoride and Papain-Based Gel for Management of MIH-affected Molar in Paediatric Patients
Molar Incisor Hypomineralization · Dental Caries · Hypomineralization of Enamel
Primary: Clinical Outcome Based on Success After Intervention on MIH Affected Molar at 6 Months — 17; 18; 17 number of Successful MIH affected molars
N/A N=102 Clinical Evaluation of Kerr SonicFill™ 2 vs 3M ESPE Filtek™ Supreme Ultra Universal Restorative
Dental Caries
Primary: Change in Esthetic Properties: Number of Teeth, Rated 1 (Most Desirable Outcome) to 5 (Least Desirable Outcome), in Each Esthetic Category — 25; 25; 2; 2 Teeth
Phase 3 N=66 Stopping Cavities Study: Diammine Silver Fluoride
Dental Caries
Primary: Dental Caries Activity — .72; .05 Proportion of arrested caries lesions
N/A N=41 Silver Diamine Fluoride Pilot Study (SDF)
Dental Caries
Primary: Assessment of Radiographic Change in Dental Cavity — 9; 11; 3; 2 Participants
Phase 3 N=98 Effectiveness of Silver Diamine Fluoride as a Treatment for Caries in Comparison to Traditional Restorative Techniques
Caries
Primary: Caries Arrest of Teeth in the SDF Group Measured by Change in Size — 10 Participants
N/A N=42 Resin Infiltration to Arrest Early Tooth Decay
Dental Caries
Primary: Number of Lesions With Progression as Measured by Pairwise (PW) Comparison (N=Lesions) — 4; 14 Lesions — p==0.003
N/A N=50 Clinical Investigation of the F-Composite 2 System in Direct Filling Therapy
Dental Caries · Unsatisfactory or Defective Restoration of Tooth
Primary: Percentage of Restored Teeth With Postoperative Sensitivity — 7 percentage restored hypersensitive teeth
N/A N=28 Adhese One F Upgrade in Direct Filling Therapy
Dental Adhesive
Primary: Number of Participants With Clinical Success — 28 Participants
Phase 2 N=75 Fibrin Sealant for the Sealing of Dura Sutures
Pathological Processes in the Posterior Fossa · Dura Defects
Primary: Incidence of Cerebrospinal Fluid (CSF) Leakage Observed After Surgery — 74.07; 78.13 percentage of participants — p=0.7159
N/A N=38 NCCL Direct Composite Restoration Performance With Self-Etch and Multimode Adhesives
Dental Adhesives/Restorations Performance
Primary: Esthetic, Functional and Biological Clinical Performance Adhesive/Adhesion Mode of NCCLs Restoration, Graded on a 5-point Scale, Using FDI Criteria at 24 Month Follow-up…
N/A N=38 Fluoride Varnish for Treatment of White Spot Lesions
White Spot Lesions
Primary: DIAGNOdent Readings at Baseline, Three and Six Months - Intergroup Comparison — 5.10; 6.01; 4.08; 5.50 units on a scale — p=0.636
N/A N=66 Clinical Evaluation of a Universal Adhesive in Noncarious Cervical Lesions
Cervical Lesions
Primary: Retention of Restorations — 38; 38; 37; 37 Non-carious cervical lesions
Phase 2 N=284 Efficacy Of A PVP-I Fluoride Varnish
Dental Caries
Primary: Dental Caries for Primary Molars Sound at Baseline — 2.3; 3.3 units on a scale — p=0.037
N/A N=237 DuraSeal Sealant Post Market Study
Elective Cranial Procedures With Dural Incision
Primary: Percentage of Subjects With Surgical Wound Complications, Central Nervous System Events, and Neurosurgical Complications Related to Unplanned Intervention or Return to…
N/A N=93 High-strength Glass-ionomer Dental Restorations
Dental Caries
Primary: Survival Rate — 39; 44; 5; 2 Restorations — p=0.262
N/A N=24 Clinical Evaluation Of A New Two-Component Self-Etch Universal Adhesive
Composite Restorations · Tooth Lesions
Primary: Retention — 100; 100; 100; 97 percentage of restorations
Phase 3 N=376 Fluoride Varnish Randomized Clinical Trial
Dental Caries
Primary: Number of Caries Incident Cases — 42; 23; 14 participants — p=<0.001