Clinical Trial Search

Primary: Postoperative Pain, as Measured by Wong-Baker Facial Rating Pain Scale ,After Routine Dental Treatment — 20; 20; 7; 11 Participants

Primary: Number of Patients Needing Rescue Medication — 32; 29 Participants

Primary: Total Pain Relief From 0 to 6 Hours (TOTPAR[6]) — 6.94; 6.21; 7.00; 14.43 units on a scale

Primary: Change in Pain Intensity From Baseline (Pre-Operative) to Immediately During the Procedure (Day 0), Measured by the Visual Analogue Scale (VAS) — 5.05; 0.64 score on a…

Primary: Sum of Pain Relief and Pain Intensity Differences From 0 to 6 Hours (SPRID 6 Hours) — 10.60; 5.87; 3.35 Units on a scale — p=0.0004

Primary: Sum of Pain Intensity Difference From 0 to 24 Hours (SPID24) Based on the 11 Point Numeric Pain Rating Scale — -96.80; -100.69; -74.96 score on a scale — p=0.0258

Primary: Pain as Assessed by a Visual Analogue Scale (VAS) — 4; 2.33 score on a scale

Primary: Sum Pain Intensity Difference Scores — -2.4292; -68.0778; -68.3533; -93.3645 score on a scale

Primary: Sum of Pain Relief and Pain Intensity Differences From 0 to 6 Hours (SPRID 6 Hours) — 16.08; 12.42; 4.63 Score on a scale — p=0.0009

Primary: Total Pain Relief Score Over the First 6 Hours Post the Initial Day 1 Dose of the Study Medication (TOPAR6) — 5.08; 16.10; 15.73; 15.67 Units on a Scale — p=<0.001

Primary: Level of Post-operative Pain (2018-2019) — 23.2; 11.56 score on VAS scale

Primary: The Visual Analog Scale (VAS) Was Used to Measures Levels of Pain. — 2; 2; 5.0 score on a scale

Primary: Opioid Prescribing at the Extraction Encounter — 443; 643; 418 Participants — p=.08

Primary: Area Under the Curve (AUC) of the Pain Scores. — 6843; 8832; 9998; 7290 mm*minutes

Primary: Change From Baseline in Cumulative Pain on the Visual Analogue Scale (VAS) at Postoperative Week 1 — 3.27; 4.35 score on a scale

Primary: Pain Intensity Difference (PID) on a 0-100 VAS — 36.5; 37.3; 37.7; 12.3 mm — p=< 0.001

Primary: Post-operative Pain Level 6 Hours on a Visual Analog Scale — 64.2; 43.1 units on a scale

Primary: Postoperative Facial Swelling (Sum of 3 Linear Distances, mm) — 122.08; 118.55; 116.90; 119.68 Millimeters (mm)

Primary: Time Weighted Sum of Pain Intensity Difference (PID) Over 10 Hours (SPID 0-10) — 5.745; 30.986 units on a scale — p=<0.001

Primary: Comparison of Pain Intensity Scores at 20 Minutes With the Baseline Pain Intensity Score During the Initial 6-hour Evaluation Period. — 14.3 millimeters — p=<0.0001

Primary: Time Weighted Sum of Pain Relief Rating (PRR) and Pain Intensity Difference (PID) Scores From 0 to 8 Hours Post-dose (SPRID 0-8): Ibuprofen + Caffeine Versus Ibuprofen…

Primary: Overall Analgesic Efficacy - Sum of Pain Intensity Difference and Pain Relief Scores Over Six Hours (SPRID6) — 529.4; 427.3; 60.0 units on a scale — p=<0.001

Primary: SPID0-8h — -50.14; -24.06; -77.54; 124.47 units on scale

Primary: Visual Analogue Scale (VAS) — 4.06; 2.68; 2.41; 2.27 score on a scale

Primary: Effect of Trypsin-Chymotrypsin on Post-operative Pain After Single Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis — 3.47; 3.53; 2.93; 6.13 score on…

Primary: Pain as Assessed by the Visual Analog Scale — 0; .33 score on a scale

Primary: Pain Intensity Visual Analog Scale (VAS)- 0-100 (0- no Pain and 100- Most Severe Pain) — 44; 41 score on a scale — p=0.156

Primary: Sum of Pain Intensity Difference (SPID) Using the Pain Intensity Visual Analog Scale (VAS) — 268.8; 230.9; 54.8 scores on a scale

Primary: Heft Parker Visual Analog Scale Pain Scale Pain Measurements — 63; 60 units on a scale

Primary: Decrease Time of Oral Pain — 9; 9; 5; 4 score on a scale