Phase 4 N=180 IV Acetaminophen for Post-Operative Pain Management in Enhanced Recovery After Surgery (ERAS) Population
Abdominal Wall Hernia · Pancreatic Diseases · Bowel Disease
Primary: Postoperative Pain Intensity — 33; 42 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=66 IV Acetaminophen for Acute Post Operative Pain in C-Section Patients
Post-operative Pain
Primary: Opioid Requirements in Cesarean Section (C-section) Patient Population — 44; 48; 58; 57 mg
Phase 4 N=204 IV Acetaminophen for Postoperative Pain After Pelvic Organ Prolapse Repair
Pelvic Organ Prolapse
Primary: Change From Baseline in Postoperative Pain — 20.5; 29.2; 20.7; 20.1 units on a scale — p=<0.05
Phase 3 N=234 OxyNorm Capsules in Post-Operative Pain Study
Postoperative Pain
Primary: Visual Analogue Scale (VAS) in Resting Stage at 6hour (6hour±20 Minutes After Administration of First Dose) — 46.21; 45.48; 20.21; 19.94 units on a scale
Phase 4 N=70 Perioperative Administration of Pregabalin for Pain After Mastectomy
Pain, Postoperative
Primary: Pain Scores (Verbal Numerical Rating Scale;VNRS) During Postoperative Hours. — 7; 5; 6; 5 Units on a scale
N/A N=16 Postoperative Peripheral Nerve Stimulation for Management of Post-amputation Pain
Phantom Limb Pain · Postoperative Pain · Neuroma
Primary: Average Phantom Limb Pain (PLP) Score — 4.1; 3.1; 2.2; 3.0 score on a scale
N/A N=90 The Impact of IV Acetaminophen on Pain After Appendectomy for Perforated Appendicitis
Perforated Appendicitis
Primary: Time Until PCA Discontinued After the Operation — 76.4; 86.7 hours
N/A N=122 Percutaneous Auricular Neuromodulation for Postoperative Analgesia
Postoperative Pain, Acute
Primary: AVERAGE Pain Measured With the Numeric Rating Scale First 5 Postoperative Days — 1; 3 units on a scale
Phase 4 N=119 Intravenous Acetaminophen for Non-Narcotic Postoperative Pain Management Following Knee Arthroscopy
Pain, Postoperative
Primary: Postoperative Pain Levels — 1.3160; 2.1362 score on a scale
Phase 4 N=343 PAIN - Postoperative Analgesia INvestigation
Postoperative Pain
Primary: Postoperative Pain as Assessed by a Numeric Pain Scale (NPS) — 5.05; 5.02 units on a scale — p=0.934
Phase 3 N=204 Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy
Hemorrhoids
Primary: Area Under the Curve (AUC) of the Numeric Rating Scale at Rest (NRS-R) Pain Intensity Scores — 359; 396 Units on a scale*hours
N/A N=148 Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery
Pain, Postoperative
Primary: Cumulative Postoperative Opiate Consumption — 2.9; 3.8; 5.7 mg
N/A N=178 Post-op Acetaminophen vs NSAID Use on Lumbar Spinal Fusion Outcomes
Lumbar Osteoarthritis · Spondylosis · Lumbar Disc Disease
Primary: Perioperative Opioid Use — 86.25; 306.6; 192.4; 88.95 oral morphine equivalents (OME) (mmg) — p=<0.001
Phase 4 N=183 IV Acetaminophen for Postoperative Pain Analgesia After Laparoscopic Hysterectomy
Pain
Primary: Postoperative Pain — 3.55; 3.11 units on a visual analog scale
Phase 2 N=141 Postoperative Pain Management in Rhinoplasty
Pain, Postoperative
Primary: Pain Intensity Visual Analog Scale (VAS)- 0-100 (0- no Pain and 100- Most Severe Pain) — 44; 41 score on a scale — p=0.156
N/A N=69 High Pain Intervention in Cesarean Sections
Other Chronic Postoperative Pain
Primary: Severity of Acute Pain — 46; 31 mm — p=0.05
Phase 4 N=515 PO vs. IV Acetaminophen Given Perioperatively for 24 hr Post-op Pain Control Following Total Hip or Knee Replacement
Post-op Pain
Primary: Total Post-operative Use of Opioids — 21.7; 21.7 Morphine milligram equivalents (MME)
N/A N=150 Pain Control After Cardiac Surgery Using Intravenous Acetaminophen
Pain
Primary: Cumulative Opioid Consumption — 97; 117 mg morphine equivalents — p=0.08
Phase 4 N=65 Postoperative Pain Control in Septum and Sinus Surgery
Post-operative Pain · Sinus Surgery
Primary: Number of Doses of Opiate (Narcotic) Pain Medication — 1.0; 1.5 number of doses
Phase 4 N=68 IV Acetaminophen as an Adjunct Analgesic in Cardiac Surgery
Acute Pain · Hyperalgesia
Primary: 24 Hour Postoperative Opioid Consumption — 62.3; 45.6 mg — p=0.024
N/A N=160 Patient-Driven Analgesic Protocol Selection for Post-Cesarean Pain Management
Postoperative Pain
Primary: Opioid Consumption in the 0-48 Hour Study Periods. — 10; 5; 10; 5 milligram morphine equivalents (MMEQ)
Phase 4 N=40 Improving Post-Operative Pain and Recovery in Gynecologic Surgery
Postoperative Pain · Opioid Use · Acetaminophen
Primary: Postoperative Pain: Standardized Pain Scale — 2.82; 3.18 score on a scale — p=.378
Phase 4 N=41 Acetaminophen's Efficacy For Post-operative Pain
Tonsillitis · Airway Obstruction · Difficulty Swallowing
Primary: Total Pain Medication — 1.7; 2.2 mg
N/A N=86 Pregabalin for the Treatment of Pain After Posterior Spinal Fusions
Lumbar Spinal Fusions
Primary: Patient Controlled Analgesia (PCA) Hydromorphone Usage — 44; 39 mL
N/A N=100 Perioperative Pain Management In Spine Surgery Patients: Part I
Pain
Primary: Immediate Postoperative Pain Control — 6.6; 6.8 score on a scale
Phase 3 N=580 Effect of Intravenous Acetaminophen on Postoperative Opioid-related Complications
Postoperative Pain
Primary: Duration of Hypoxemia — 0.7; 1.1 min/h — p=0.29
Phase 4 N=99 Perioperative Administration of Pregabalin for Pain After Robot-assisted Endoscopic Thyroidectomy
Pain, Postoperative
Primary: Pain Scores (VNRS) at 1, 6, 24, 48 Hours Postoperatively. — 6; 6; 3; 2 VNRS
Phase 4 N=200 Assessment and Prevention of Acute Post-herniotomy Pain
Hernia
Primary: Analgesic Efficacy — 26.5; 32.3 percentage of patients with NRS≥4
Phase 4 N=160 Management of Postoperative Pain After Total Knee Replacement.
Postoperative Pain · Knee Replacement Arthroplasty
Primary: Post-Operative Pain — 2.9; 3.0 units on a scale — p=0.76
Phase 3 N=60 Analgesic Efficacy of Repeated Doses of Intravenous (IV) Acetaminophen in Post-operative Pediatric Spine Fusion Patients
Pain, Postoperative
Primary: Total Opiate Requirement — 1.19; 1.01 mg/kg