N/A N=190 Opioid Prescribing After Cesarean Delivery
Surgery · Opioid Use
Primary: Unused Opioids — 5; 10 oxycodone 5mg tablets
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=27 Prescription Opioid Effects in Abusers Versus Non-Abusers
Opioid-Related Disorders · Substance-Related Disorders
Primary: Breakpoint — 25; 400; 1400; 850 Mouse Clicks
Phase 2 N=51 Prescription Opioid Abuse Among Pain Patients: Predictors of Relapse
Opioid Dependence
Primary: Number of Participants Retained in Study — 18 participants
N/A N=204 Safety & Prevention Outcomes Study
Drug Overdose · Opioid-Related Disorders
Primary: Overdose Risk Behavior — -1.54; -0.51 Scores on a scale
N/A N=49 Consensus-based Algorithms to Address Opioid Misuse Behaviors Among Individuals Prescribed Long-term Opioid Therapy
Opioid Misuse · Chronic Pain
Primary: Feasibility of Algorithms — 7; 13 Participants
N/A N=115 Opioid Treatment and Recovery Through a Safe Pain Management Program
Depression · Opioid Use · Chronic Pain
Primary: Odds of Morphine Equivalent Daily Dose (MEDD) of Opioid Prescription >=50 mg — 0.209; 0.417; 0.185; 0.364 odds of prescription high dose — p=0.956
Phase 4 N=304 Comparing Opioid Prescription Patterns in Total Joint Arthroplasty Patients
Postoperative Pain
Primary: Morphine Milligram Equivalents (MME) of Oxycodone Tablets Taken by Patient — 1089.7; 777.1 Morphine Milligram Equivalents (MME)
N/A N=533 A Digital Intervention to Prevent the Initiation of Opioid Misuse in Adolescents in School-based Health Centers
Opioid Misuse
Primary: Percentage Reporting 'Great Perceived Risk of Harm' From Opioid Misuse — 66; 53 Participants
N/A N=127 Post-op Crowd Sourcing Health Data Via Text-messaging
Orthopedic Surgery · Opioid Use · Acute Injuries Knee
Primary: Number of Opioid Tablets Taken Within 28 Days — 8.05; 11.55 number of pills taken
N/A N=851 Behavioral Insights to Encourage Judicious Prescribing of Opioids
Substance-Related Disorders
Primary: Average Change Over Time in Dispensed Narcotics — 347.65; 350.09; 288.36; 318.60 Morphine milligram equivalents — p=<0.05
Phase 2 N=120 Ambulatory Gynecologic Surgery: Finding the Optimal Opioid Prescription
Surgery
Primary: Number of Oxycodone Tablets Used Day 1 — 1.0; 1.0 Oxycodone Tablets — p=.87
N/A N=1,804 A High School Program for Preventing Prescription Drug Misuse
Prescription Drug Abuse · Substance Abuse · Substance Use (Drugs, Alcohol)
Primary: Prescription Drug Misuse (i.e., Prescription Drug Use Without a Doctor's Prescription) — 1.06; 1.12; 1.11; 1.13 score on a scale
N/A N=299 Primary Care Intervention to Reduce Prescription Opioid Overdoses
Pain · Drug Overdose · Opioid Use Disorders
Primary: Overdose Risk Behaviors — 1.31; 1.21; 1.45; 1.25 score on a scale
N/A N=503 Scenario Tailored Opioid Messaging Program (STOMP) to Improve Risk Understanding in Young Adults
Pain, Postoperative · Medication Adherence · Opioid Use
Primary: Opioid Risk Perception — 31.4; 31.1; 32.8; 30.02 score on a scale — p=.001
N/A N=111 Opiate Prescribing Guidelines Following Hip Arthroscopy
Hip Injuries
Primary: Numeric Pain Rating Scale (NPRS) Pain Scores — 4.2; 4.0 score on a scale
N/A N=541 Encouraging Judicious Prescribing of Opioids in Los Angeles County
Substance-Related Disorders
Primary: Average Weekly Change in Morphine Milligram Equivalents (MME) Dispensed — 157.70; 157.81; 103.16; 89.96 Estimated average weekly MME dispensed — p=<0.05
N/A N=196 Discharge Opioid Education to Decrease Opioid Use After Cesarean
Opioid Use
Primary: Opioid Use — 7.5; 10 hydrocodone tablets
N/A N=112 Co-Use of Opioid Medications and Alcohol Prevention Study
Alcohol Drinking · Opioid Use
Primary: Alcohol Use Reductions — 11; 12; 1; 1 Participants
Phase 2 N=16 A Study to Evaluate the Abuse Potential of Oxymorphone Compared to Other Mu Opioid Agonists.
Opioid Use Disorder
Primary: Positive Subjective Drug Effects (i.e., Drug "Liking"). — 52.1; 57.5; 71.8; 71.5 units on a scale — p=.0001
N/A N=102 Reducing High School Athletes' Prescription Opioids Misuse and Diversion Through the Student Athlete Wellness Portal
Prescription Opioid Misuse
Primary: Usability — 3.49 score on a scale — p=.001
N/A N=125 Parental Perceptions on Prescription Opioid Use
Orthopedic Disorder
Primary: Comfort With Child Receiving Opioids During Surgery — 5; 84; 36 Participants
N/A N=555 Application of Economics & Social Psychology to Improve Opioid Prescribing Safety Trial 1: EHR Nudges
Opioid Abuse, Unspecified
Primary: Change in Average Per-clinician Log Total Weekly MME Between Baseline and Intervention for Opioid Naïve and At-Risk Patients (Below 50 MME Daily Dose Rxs) — -0.14; -0.05…
N/A N=5,411 Comparing State Payer Strategies to Prevent Unsafe Opioid Prescribing
Opioid Use · Opioid-Related Disorders
Primary: Subacute Phase - More Than 7 Days of Opioids — 1.9; 12.2 % of participants — p=<.001
N/A N=129 STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery Trial
Postoperative Pain · Opioid Use · Prolapse; Female
Primary: Percentage of Patients Satisfied With Pain Control at 6 Week Postoperative Visit — 59; 58 Participants
Phase 1 N=11 Prescription Medication Interactions
Opioid Use · Sedative Use
Primary: Change in Subject-Rated Outcome: Visual Analog Scale (VAS) Drug Liking — 7.40; 39.00; 40.80; 24.50 Score on a scale — p=<0.0001
N/A N=286 Guiding Aging Long-Term Opioid Therapy Users Into Safer Use Patterns
Pain · Opioid Use
Primary: Count of Referrals to Non-opioid Care — 3.075; 3.61 Count of referrals — p=0.213
N/A N=479 Text Intervention to Facilitate Secure Storage and Disposal of Prescription Opioids
Opioid Misuse
Primary: Percentage of Participants Who Securely Stored Their Opioid Medication During Treatment — 48; 29; 140; 181 Participants — p=0.003
N/A N=60 Reducing Prescription Opioid Misuse: ROPEs Pilot Trial
Knowledge, Attitudes, Practice
Primary: Methodological Feasibility: Recruitment Rate — 60 Participants
Phase 3 N=5,521 Opioid Prescription After Cesarean Trial
Pregnancy Related · Opioid Use · Pain
Primary: Number of Participants With Worst Pain Score of Moderate to Severe on the Brief Pain Inventory — 1497; 1535 Participants
N/A N=140 Opioid Consumption and Disposal After Shoulder Arthroplasty
Opioid Use
Primary: Difference in Proportion of Participants With > 10 Pills Left Unused. — 49; 47 Participants