Clinical Trial Search

Primary: Positive and Negative Syndrome Scale (PANSS) — 72.9 score on a scale

Primary: Change in Biomarkers of Treatment Response: Dorsal Caudate (DCA) Gamma Amino Butyric Acid (GABA) Levels — -0.65; .0037 institutional units — p=<0.01

Primary: Number of Participants Demonstrating Improvement in Substance Use — 3; 3 participants

Primary: PANSS Total — 77.9; 80 units on a scale — p=0.02

Primary: Metacognition Assessment Scale-Abbreviated (MAS-A) — 11.53; 14.22; 14.22; 14.25 score on a scale

Primary: The State Social Paranoia Scale (SSPS) — 9.72; 3.90 The change score of SSPS (pre - post) — p=0.023

Primary: Change of Resting-state Functional Connectivity (rsFC) by Active and Sham rTMS — 0.018; 0.007 z score of functional connectivity

Primary: Social Functioning Scale (SFS) Change — 1.28; 0.19; 1.56; 0.32 score on a scale

Primary: Genetic Linkage — 5.2 log (odds ratio) — p=<0.001

Primary: Loss of Effect Over Time — 7; 15; 6; 3 Participants

Primary: Mean Heinrichs-Carpenter Quality of Life Scale Scores Over Time — 51.25; 55.13; 59.15; 60.08 score on a scale — p=0.0145

Primary: Prepulse Inhibition (PPI) — 22.629; 41.162; 50.626; 50.626 % inhibition of startle

Primary: Error Percentage in Antisaccade Task — 22.6; 29.1 Error Percentage in Antisaccade Task — p=<0.05

Primary: Onset of Psychosis — 10; 14 percentage of sample converting

Primary: Average Over Time of Intensity of Cannabis Use (Used to Evaluate Treatment Efficacy) — 0.02; 4.56 Joints per week — p=.088

Primary: Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT) — 87.30; 87.30; 88.46; 89.23 units on a scale — p=< .05

Primary: Biomarkers — 287.37; 340.83; 492.33; 420.17 pg/mL

Primary: Change From Baseline in Positive and Negative Syndrome Scale (PANSS) Total Score at Week 26 — 68.9; 28.1 Units on a scale

Primary: Wisconsin Card Sort Percent Perseverative Errors (Standard Score) — 87.54; 87.88; 91.80 standard score units — p=<.97

Primary: Positive and Negative Symptom Improvement — 41.3; 40.3; 36.6; 37.3 score on a scale

Primary: Change From Baseline in the Positive and Negative Syndrome Scale (PANSS) Total Score at Week 13 or Early Discontinuation — 83.5; 85.7; 6.9; -3.1 units on a scale…

Primary: fMRI Connectivity of Regions of Interest (ROI) Within the Brain Reward Circuitry (BRC). — .40; .33 Z score

Primary: Changes in Positive Schizophrenia Symptoms — 3.21; 3.30; 3.04; 2.89 units on a scale — p=.30

Primary: Total Plasmalogen Levels in the Lipid Profile — 57.65; 59.57; 75 nmoles/gram — p=0.0149

Primary: Change From Open-label Baseline in Modified Scale for the Assessment of Negative Symptoms (SANS-18) Total Score at Week 10 Open-label Phase, Last Observation Carried…

Primary: Social Attention: Social Engagement Latency (SEL) — 21618 msec

Primary: Change in BOLD Signal in Anterior Cingulate Cortex — -0.0188; 0.0124 BOLD signal change (Mismatch vs. Match)

Primary: End-of-session Carbon Monoxide — 62.7; 43.0 parts per million (ppm)

Primary: Time to Relapse or an Impending Relapse — 0; 3; 1; 14 relapses

Primary: Plasticity Improvement (Change in Tone Matching Threshold) — 13.9; 5.3; 11; -0.05 log ratio