N/A N=60 Conscious Sedation for Epilepsy Surgery
Epilepsy
Primary: Patients Satisfaction — 6.33; 6.45 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=86 Sedation and Pain (The Effect of IV Sedation on Pain Perception)
Pain
Primary: Pain Rating Change — -0.253; 0.762; -0.346 units on a scale
Early Phase 1 N=300 Sedation Regimens in GI Endoscopy
Anesthesia · Endoscopy · Colonoscopy
Primary: Pain Felt During the Procedure — 0.29; 0.30 score on a scale
Phase 4 N=50 Alternative Sedation During Bronchoscopy
Sedation
Primary: Decreased Minute Ventilation — 0.736; 0.764 percentage of baseline — p=<0.0001
Phase 3 N=50 Sedation Using Intranasal Dexmedetomidine in Upper Gastrointestinal Endoscopy
Gastrointestinal Disease
Primary: Consumption of Rescue Patient Controlled Propofol — 42.4; 28.6 mg
N/A N=110 Sedline EEG Guided Depth of Anesthesia
Anesthesia · Surgery
Primary: Total Average Anesthetic — 1.1890; 1.2906 percentage of sevoflurane
N/A N=11 Sedation in Patients at Risk for Upper Airway Collapse
Obstructive Sleep Apnea
Primary: Respiratory Disturbance Index — 57.52; 21.32 events per hour
N/A N=36 Sedatives' Effects on Neurological Function in Patients With Eloquent Area Glioma
Glioma
Primary: Task Completing Time Change Between Sedation and Baseline Measured by 9-hole Peg Test — 27.8; 19.1; 54.3; 21.4 seconds — p=<0.01
N/A N=10 Effects of Two Different Sedation Regimes on Auditory Evoked Potentials and Electroencephalogram (EEG)
Conscious Sedation · Deep Sedation · Critical Care
Primary: Amplitudes (in Micro Volts) of Acoustic Event Related Potentials (Time-locked Amplitudes in the Electroencephalogram 100 Milliseconds After the Acoustic Stimulus…
Phase 4 N=107 Moderate Versus Deep Procedural Sedation With Propofol in the Emergency Department
Pain
Primary: Patients With Clinical Signs of Respiratory Depression or Sub Clinical Respiratory Depressions Measured by Capnography and Pulse Oximetry. — 22; 21 Participants
Phase 4 N=105 Sedation Methods During Cataract Surgery
Phacoemulsification · Cataract
Primary: Eye Mobility During Surgery (See Link to Study Protocol for Scale) — 1.39; 1.41; 1.31 units on a scale
Phase 4 N=50 Dexmedetomidine for Sedation of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Bronchoscopy
Primary: Hypoxemia During Maintenance — 8; 14 Participants
N/A N=65 The Effect of Sedation on Eye Movements
Saccadic Eye Movements
Primary: Dynamic Eye Movement Measures — -25; -115; -90; 10 (degrees/second)
Phase 3 N=60 A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients
Anxiety, Dental · Dental Decay
Primary: Incidence of Adverse Sedation-Related Events in Musculoskeletal System During Sedation — 2.8; 3; 2.5500 score on a scale — p=0.016
N/A N=1,771 The Emergency Department Sedation Pilot Trial
Mechanical Ventilation · Respiratory Failure
Primary: Participant Recruitment — 196; 219 Participants
N/A N=73 Effect of Sedation on Diagnostic Injections
Sacroiliac Joint Pain · Sympathetically Maintained Pain
Primary: Pain Score — 2.2; 3.4 units on a scale
Phase 4 N=68 Etomidate vs. Midazolam for Sedation During ERCP
Choledocholithiasis · Cholangiocarcinoma · Pancreatitis
Primary: Number of Intervention — 1.9; 7.5 Number of intervention — p=0.05
Phase 2 N=15 Testing the Feasibility of Patient Controlled Sedation for Ventilated ICU Patients
Acute Respiratory Failure · Anxiety
Primary: Aggregate Sedative Exposure During PCS Use (up to 5 Days). — 4; 3.5 units on a scale
Phase 4 N=144 A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation
Anesthesia
Primary: Respiratory Events Requiring Intervention — 17; 2 Participants
Phase 4 N=40 Sedation Effect of Dexmedetomidine Versus Remifentanil to Fibreoptic Intubation
Intubation; Difficult
Primary: Endoscopy Scores — 3; 2 units on a scale
N/A N=53 Sedation During Muscle Biopsy in Patients With Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy
Primary: Time to Sedation Score of 3-4 — 3.7; 2.8 minutes
N/A N=10 Phamacological Reversal of Airway Instability During Sedation
Upper Airway Obstruction
Primary: AHI - Apnea Hypopnea Index — 14.5; 27.9; 11.3; 12.1 events per hour
Phase 4 N=798 Ancillary Effects of Dexmedetomidine Sedation After Cardiac Surgery
Heart Disease
Primary: Number of Patients With Atrial Arrhythmia — 121; 134 Participants — p=0.34
N/A N=121 Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia
Emergence Delirium
Primary: Emergence Agitation — 3.9; 2.5 Score on a scale — p=0.001
Phase 4 N=304 Adjunct Sedatives in Endoscopic Ultrasound (EUS) and Endoscopic Retrograde Cholangiopancreatography (ERCP) Procedures
Endoscopic Ultrasound (EUS) · Endoscopic Retrograde Cholangiopancreatography (ERCP)
Primary: Average Percentage of Sedation Failures — 14; 13; 5 percentage of participants
N/A N=200 Randomized Trial of Diphenhydramine Versus Continued Midazolam in "Difficult-to-sedate" Patients Undergoing Colonoscopy
Sedation · Endoscopy
Primary: Number of Patients Who Achieve Adequate Sedation to Allow Colonoscopy (Defined as MOAA/S ≤3) — 27; 65 participants — p=<0.001
N/A N=108 Comparison of Depth of Sedation Performance Between SedLine and Comparator Device During General Anesthesia
Anesthesia
Primary: Correlation of Sedation Indices Performance Across Anesthesia Range — 0.8314 Pearson r
N/A N=180 Improving Sedation of Children Undergoing Procedures in the Emergency Department
Anxiety
Primary: Change in CHEOPS Score Measured Level of Sedation From Baseline (Presentation in ED, Before Sedation) to Start of Procedure (Laceration Repair). — 2; 2; 1 Scores on a…
Phase 4 N=36 Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure
Sepsis · Respiratory Failure · Agitation
Primary: Duration of Mechanical Ventilation — 5; 3 days — p=0.107
Phase 4 N=120 Diphenhydramine as an Adjunctive Sedative in Patients on Chronic Opioids
Colonoscopy · Adjunct Anesthesia Medication
Primary: Dosage of Fentanyl — 125.4; 126.9 (μg)