N/A N=820 Message Testing in Older Adult Smokers
Smoking · Smoking Cessation
Primary: Emotional Response — 2.73; 2.97; 1.26; 2.17 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=33 Effects of Exercise Intervention on Aging-related Motor Decline
Aging · Exercise
Primary: Estimate Cardiovascular Efficiency After Aerobic Exercise — 24.01; 31.2; 32.3 ml/kg(min) — p=.001
N/A N=47 Stress-Reactivity and Cannabis Use in Cannabis-Using Older Adults
Cannabis Use
Primary: Global Cognitive Ability (GCA) — -1.99; -0.82 Standard score (Z-score) — p=0.005
N/A N=62 Zoomers for the Capital Region: A Peer-Led Exercise Program for Aging Adults
Aging · Fall
Primary: Balance — 26.7; 27.9; 34.7; 29.7 score on a scale
N/A N=839 Message Testing in Aging African American Smokers
Smoking · Smoking Cessation
Primary: Motivation to Quit Smoking — .3052; .3220; .3202; .4378 score on a scale
N/A N=1,377 The Effects of Ageing on the 'Pharmacokinetic and Clinical Observations in People Over Fifty'
HIV Positive · Ageing
Primary: The Prevalence of Reported Aches and Pains in the Last Month Across the 3 Age Groups — 473; 224; 188 participants
N/A N=385 Advance Planning for Home Services for Seniors
Alzheimers, Falls, Aging in Place
Primary: Planning Behavior Score at 1-month — 16.97; 16.80; 17.19; 15.88 units on a scale — p=0.0054
Phase 3 N=302 Enhancing Fitness in Older Pre-diabetic Veterans
Impaired Glucose Tolerance · Obesity · Diabetes
Primary: Fasting Insulin — 10.26; 10.39 uIU/ml
N/A N=186 Internet-based Conversational Engagement Clinical Trial
Aging · Mild Cognitive Impairment
Primary: Intervention Efficacy for High Dose : Global Cognitive Function as Calculated From the Change From Baseline to Month 6 — 0.40; 0.07; 1.46; -0.44 units on a scale — p=0.87
Phase 2 N=300 A Study of High-Dose Trivalent Inactivated Influenza Vaccine in Adults 50 to 64 Years of Age
Influenza
Primary: Geometric Mean Titers (GMTs) of Vaccine Antibodies Before and After Vaccination With Either Fluzone® High-Dose or Fluzone® Vaccine. — 40.5; 28.8; 36.4; 41.4 1/dilution…
Phase 3 N=1,533 A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus Given to Adults 50-59 Years of Age, Including Adults at Increased Risk of Respiratory Syncytial Virus Lower Respiratory Tract Disease, Compared to Older Adults 60 Years of Age and Above
Respiratory Syncytial Virus Infections
Primary: RSV-A Neutralization Titers Expressed as Group Geometric Mean Titer (GMT) in Healthy Participants Compared to OA-RSV Group — 7906.0; 7518.9 Titer
N/A N=181 A Personalized Health Behavior System
Social Isolation · Aging · Physical Activity
Primary: VO2 Max — 16.6; 16.8; 15.7; 18.5 mL/kg/min — p=.82
Phase 4 N=40 Genomics and Epigenomics of the Elderly Response to Pneumococcal Vaccines
Pneumonia · Aging
Primary: Pneumococcal-specific Antibody Responses — 72.1; 79.4; 128.9; 120.9 log2 titer
N/A N=37 Pilot Investigation of a Multinutrient Supplement on Skin Aging and Aging Metabolites in Healthy Women
Skin Diseases
Primary: Fold Change in Long Chain Fatty Acids — 1; 0.76 Fold Change in long chain fatty acids
Early Phase 1 N=144 Inflammation and Daily Life Study
Inflammation
Primary: Loneliness — 47.9; 46.9; 46.8; 44.6 score on a scale
N/A N=59 Loving Kindness Meditation Among Adults 50 Years and Older
Loneliness
Primary: Change in Loneliness — 4.64; 4.65; 4.82; 4.62 units on a scale
N/A N=896 Understanding the Impact of Neighborhood Type on Physical Activity in Older Adults
Cardiovascular Diseases · Heart Diseases
Primary: Physical Environment Factors Using Geographic Information Systems [GIS] — 1.3; 1.9; -2.1; -1.6 units on a scale
Phase 2 N=25 Positron-Emission Tomography With Vesicular Monoamine Transporter Ligand ([18F]-DTBZ) In Healthy Elderly And Young Subjects
Healthy
Primary: Age-Dependent Change in Striatal 18F-DTBZ Uptake of Healthy Subjects. — 0.05 SUVR
N/A N=115 Healing Hearts and Mending Minds in Older Adults Living With HIV
HIV · Cardiovascular Disease · AIDS
Primary: Stroop Color and Word Test Score — 31.17; 28.89; 32.87; 30.69 number of correct responses
Early Phase 1 N=101 Dose Response Study of Aerobic Exercise in Older Adults
Alzheimer's Disease
Primary: Visuospatial Processing — -.02; .19; .08; .29 units on a scale
Phase 2 N=37 A Study of Muscle Strength Maintenance in Older Adults
Sarcopenia
Primary: Change From Baseline in Isokinetic Strength — -4.90; -4.73 Newton — p=0.97
N/A N=60 Mindfulness Training in Healthy Older Veterans
Aging
Primary: Geriatric Depression Scale Change Score — .89; 0.50 score on a scale
N/A N=300 A Personalized Reminder Information and Social Management System
Social Isolation · Social Support (Formal and Informal) · Well-being/Quality of Life
Primary: Change in Social Isolation Measured by Friendship Scale — 18.75; 19.72; 18.94; 20.27 units on a scale
N/A N=322 The Pitt Retiree Study: A Diabetes Prevention Program for Medicare Eligible Older Adults
Obesity · Cardiovascular Risk Factor · Eating Behavior
Primary: Change in Bodyweight — -7.4; -6.1 percent weight change — p=0.01
N/A N=78 Aerobic Exercise and Cognitive Training in Older Adults
Sedentary Lifestyle
Primary: Change Executive Language Functions (Category Verbal Fluency) — 5; -1 Number of Fluent Words within 60 seconds
N/A N=12 Health & Aging Brain Study: Health Disparities TAU Project
Brain Aging in Mexican Americans
Primary: Tau Accumulation Measured by PET Imaging — 12 Participants
N/A N=73 Seniors Health and Activity Research Program-Pilot
Cognitive Function
Primary: Composite Cognitive Function in Z-scores (i.e. Which Converts Raw Data to Standard Deviation (SD) Units: [Score-mean]/SD]). This Composite is Formed by Averaging the…
N/A N=90 Health, Aging and Later-Life Outcomes
Aging
Primary: Number of Participants That Sustained >10% Caloric Restriction — 7; 12 Participants
N/A N=314 Reducing Cardiometabolic Risk and Promoting Functional Health in Older Adults With Obesity and Prediabetes
Obesity · PreDiabetes · Aging
Primary: Change in Bodyweight — -7.4; -6.1 percentage of bodyweight change — p=0.196
N/A N=9 Translational Control of Anabolic Resistance in Aging Muscle
Physical Inactivity
Primary: Lean Mass — 403 grams