Phase 2 N=21 Occlusal Adjustment as Treatment for Chronic Orofacial Pain
Temporomandibular Joint Disorders · Orofacial Pain
Primary: Visual Analogic Scale for Pain Intensity (0-10) — 6.52; 4.8; .81; 2.05 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=24 Duloxetine for Treatment of Painful Temporomandibular Joint Disorder
Temporomandibular Joint Disorders
Primary: Spontaneous Pain as Measured by Visual Analog Scale at Baseline and at End of 6 Weeks. — 42.9; 51.4; 30.4; 44 units on a scale
N/A N=80 Conservative Treatment of Patients With Temporomandibular Disorders
Temporomandibular Disorders
Primary: Patient-Rated TMD Pain, an 11 Point Numerical Rating Scale (NRS) — 0.9; 1.4; 1.6; 0.7 units on a scale
N/A N=191 Managing Temporomandibular Disorder (TMD) Symptoms
Temporomandibular Joint Disorders
Primary: Characteristic Pain Intensity (Characteristic Intensity of Facial Pain) — 3.1; 2.9; 3.6 units on a scale — p=0.19
N/A N=24 Motor Cortex as a Research & Therapeutic Target in TMD
Temporomandibular Joint Disorders
Primary: Number of Participants With Pain Relief as Measured by Visual Analog Scale (VAS) Decrease of 50% or Greater From Baseline — 4; 9 participants
N/A N=80 Tailored Self-Management of Temporomandibular Disorders (TMD) Using Health Information Technology
Temporomandibular Joint Dysfunction Syndrome
Primary: Assessing Graded Chronic Pain Severity Evaluation Feasibility of the PACT Program — -12; -19 units on a scale
N/A N=9 Transcranial Magnetic Stimulation for Facial Pain
Trigeminal Nerve Injuries · Post-herpetic Neuralgia · Facial Pain
Primary: Visual Analogue Scale (VAS) — 5.4 score on a scale
Phase 2 N=200 Study of Orofacial Pain and PropRANOlol
Temporomandibular Disorders
Primary: Change in the Weekly Mean Pain Index After 9 Weeks of Treatment — -13.9; -12.1 units on a scale — p=0.414
N/A N=74 The Effectiveness of a Physiotherapy Technique in Patients With Chronic Myofascial Temporomandibular Disorder
Myofascial Pain Syndrome · Temporomandibular Disorder
Primary: Changes of Perceived Pain Between Three Time Points (Baseline, Post-treatment, and 3 Months Later) and Between Groups (Sham Simulation and Pressure Release Technique)…
Phase 3 N=58 Biofeedback-Based Cognitive Behavioral Treatment for Temporomandibular Disorders
Temporomandibular Disorders
Primary: Pain Intensity (German Pain Questionnaire; Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD)) — 5.40; 5.53; 3.90; 3.89 units on a scale
Phase 2 N=79 Traditional Chinese Medicine (TCM) for Temporomandibular Dysfunction (TMD): A Whole Systems Multi-site Trial
Temporomandibular Dysfunction
Primary: Characteristic Facial Pain Score — 6.52; 6.55; 5.11; 5.47 units on a scale — p=0.020
N/A N=21 TMD Online Program for Pain Management
TMD/Orofacial Pain
Primary: Treatment Feasibility — 18 Participants — p=.05
Phase 2 N=140 Comparison of Psychological and Pharmacological Treatments for Pain Due to Temporomandibular Joint Disorder (TMD)
Temporomandibular Joint Disorders
Primary: Average Pain — 4.7; 4.4; 4.5; 5.0 units on a scale — p=<.05
Phase 2 N=51 Effectiveness of Photobiomodulation and Manual Therapy Alone or Combined in TMD Patients
Temporomandibular Disorder
Primary: Change From Baseline in Visual Analogic Scale (VAS) for Pain — 4.1; 4.4; 5.2; 3.3 millimeters — p=<0.001
Phase 4 N=200 Efficacy of Naproxen-codeine, Naproxen+Dexamethasone, and Naproxen on Myofascial Pain
Temporomandibular Disorder
Primary: Pain Evaluation — 6.38; 6.93; 5.76; 5.49 score on a scale
Phase 2 N=152 Treatment Outcomes for Temporomandibular Disorders (TMD) Via the Clayton Intra-aural Device (CID) Clinical Trial
Temporomandibular Disorders
Primary: Change From Baseline In Craniomandibular Index (CMI) Scores At 3 Months (In A Scale) — .23; .20 Units on a scale — p=<0.0096
Phase 2 N=30 Safety and Efficacy of Erenumab-aooe in Patients With Temporomandibular Disorder
Temporomandibular Disorder
Primary: Brief Pain Inventory (BPI) Pain Severity at 20 Weeks — 1.72; 1.42 score on a scale — p=0.567
N/A N=14 Study of a New Technique to Improve the Symptoms of Orofacial Discomfort in Patients With Peripheral Facial Paralysis
Peripheral Nerve Facial Nerve Paralysis · Facial Nerve Diseases · Orofacial Pain
Primary: The Visual Analog Scale for Pain Was Used to Grade Discomfort in Chewing After the Installation of Facial Paralysis. Level Zero is the Lack of Discomfort and 10 is the…
Phase 2 N=60 The Effect of Opioid-Free Anesthesia in TMJ Surgery
Temporomandibular Joint Disorders
Primary: Pain Score — 4.9; 4.4 units on a scale
N/A N=55 Analgesic Ointment on Temporomandibular Joint and Masticatory Muscle Pain
Temporomandibular Disorders
Primary: The Efficacy in the Treatment of TMJ and Muscle Pain — 21.93; 40.81 units on a scale
N/A N=28 Immediate Effect of Ultrasound Therapy on Bilateral Masseter Myalgia: Randomized Single Blinded Investigational Trial
Temporomandibular Joint Dysfunction Syndrome
Primary: Self Report of Pain — -.86; -2.0; -1.4; -1.3 Scores on pain intensity scale — p=0.17
N/A N=171 Assessing a New Jaw Support Device During Third Molar Extractions
Impacted Third Molar Tooth · Temporomandibular Disorder
Primary: Occurrence of Pain at Follow-up With Wide Opening, or Pain in the Temple, Jaw Joint or Jaw Muscles. — 26; 32; 54; 53 Participants
N/A N=48 Acute Effects of Alcohol Use on Chronic Orofacial Pain
Temporomandibular Joint Disorders
Primary: Pressure Pain Threshold — 4.56; 5.27; 3.81; 4.51 lbf — p=.99
N/A N=30 Efficacy of Photobiomodulation Therapy Using 980nm Versus 635nm Diode Lasers for Treatment of Myofascial Pain
Myofascial Pain Syndrome
Primary: Pain Intensity Reduction — 7.6; 7.8; 3.2; 2.5 "units on scale — p=0.05
Phase 3 N=75 Botulinum Toxin Versus Placebo Injections to Temporalis and Masseter Muscles
Pain, Head · Pain Syndrome · Temporomandibular Disorder
Primary: Change in Jaw Pain as Reported by Patient on Visual Analog Scale (VAS) — 58; 54; -19; -14 score on a scale — p=0.80
N/A N=81 Myofunctional Training for Obstructive Sleep Apnea Patients After Transoral Robotic Surgery
Sleep Apnea, Obstructive
Primary: Apnea Hypopnea Index (AHI) — 44.89; 44.65; 36.87 events per hour — p=<0.05
N/A N=74 Sleep Disordered Breathing and Chronic Pain
Sleep Apnea Syndromes
Primary: Number of Sleep Related Events Per Hour — 38.8; 17.4; 4.5; 7.6 events/hour — p=<0.001
Early Phase 1 N=22 Developing Brain Stimulation as a Treatment for Chronic Pain in Opiate Dependent
Chronic Pain · Opiate Dependence · Lower Back Pain
Primary: Change in Quantitative Pain Testing Following Active TMS Compared to Baseline — 1.4; .3 Change from Baseline (degrees C) — p=.83
N/A N=20 Intra-articular Injection in Arthroscopic Management of Temporomandibular Diseases
Temporomandibular Joint Disorders
Primary: Maximum Interincisal Opening (MIO) Measurements — 23.1; 27.9; 33.8; 35.6 Millimeter
N/A N=143 Pain and Sensory Changes Assessment in HIV+ Patients
HIV Infections
Primary: Number of Participants With Chronic Myogenic Pain, TMJ Disoder, and Burning Mouth Syndrome — 72; 8; 37; 7 Participants