Clinical Trial Search

Primary: Area Under the Curve (AUC) of Numeric Rating Scale (NRS) Pain Intensity Scores Through 48 Hours — 178.9; 181.6 units on NRS scale*hr — p=0.8661

Primary: Occurrence of Pain at Follow-up With Wide Opening, or Pain in the Temple, Jaw Joint or Jaw Muscles. — 26; 32; 54; 53 Participants

Primary: Postoperative Facial Swelling (Sum of 3 Linear Distances, mm) — 122.08; 118.55; 116.90; 119.68 Millimeters (mm)

Primary: Sum of Pain Intensity Difference (SPID) Using the Pain Intensity Visual Analog Scale (VAS) — 268.8; 230.9; 54.8 scores on a scale

Primary: Onset of Anesthetic — 1.5; 1.5 minutes — p=0.192

Primary: Total Pain Relief at 6 Hours Post Dose (TOTPAR 6) — 2.45; 4.37 units on a scale

Primary: Radiographic Bone Changes — -1.12; -2.60; -1.16; -.158 millimeter

Primary: Total Pain Relief From 0 to 6 Hours (TOTPAR[6]) — 6.94; 6.21; 7.00; 14.43 units on a scale

Primary: Amount of Bleeding in Cubic Centimetre — 11.95; 8.75 Cubic Centimeter

Primary: Mean of Pain Intensity Based on the Visual Analogue Scale (VAS) — 37.45; 34.95; 38.84; 17.15 Scores on a Scale

Primary: Efficacy Rate (Percentage) of Patient's Impression — 64.1; 25.9 percentage of participants — p=<0.0001

Primary: Postoperative Pain — 51.4; 56.3; 60.9 score on a scale

Primary: Change in Systolic Blood Pressure (SBP) — 115.04; 112.04; 113.58; 113.58 mm Hg — p=0.579

Primary: Changes in Width of Extraction Site (Ridge) — 0.7; 1.3 mm — p=<0.05

Primary: Total Pain Relief Based on Numerical Rating Scale (NRS) Score — 17.7; 12.4; 13.3 Units on a scale — p=<0.0001

Primary: Number of Participants With Successful Injection Technique Assessed by Verbal Rating Scale (VRS) — 16; 37; 29; 26 Participants

Primary: Analgesic Efficacy, as Measured by the Sum of Pain Intensity Differences (SPID) Scale — 14.80; 0.40 Units on a scale — p=<0.0001

Primary: Number of Participants That Had an Implant That Survived 3 Years After Implant Placement — 3; 6; 7 participants

Primary: Change in Buccal Plate Thickness From Baseline to Month 6 — 1.85; 1.25 mm — p=0.11

Primary: Summed Pain Intensity Difference Over 0 to 12 Hours (SPID12) After Time 0 — 51.84; 56.33; 19.11 score on a scale*hours — p=<0.0001

Primary: Bone Volumetric Reduction From Baseline to 20 Weeks Post-extraction — 73.26 mm3

Primary: Number of Definitive Upper Canines That Erupt Spontaneously up to 18 Months of Follow up — 3; 2; 1; 4 number of canines

Primary: Ranked Endpoints : 1. Sum of Pain Intensity Differences at 6 Hours (SPID0-6h) — 8955.4; 8458.0; 5290.7 score on a scale — p=0.0031

Primary: Number of Participants With a PAI Score of < 3, = 3, or = 4 or 5 — 51; 3; 0 Participants

Primary: Percent New Bone Formation — 41; 25; 26 percentage of new bone formation

Primary: Mid Facial Mucosal Level at Implant Site — 0.36; 0.49 mm

Primary: Bone-fill in Grafted Post-extraction Sockets Versus Bone-fill in Non-grafted Post-extraction Sockets — 0.43; 0.27; 0.36; 0.28 mm

Primary: Enamel Hardness — 348.4; 351.6; 354.5 Vickers hardness kg f/mm2 — p=0.231

Primary: Evaluation of the Effect of Black Tea Extract-Impregnated Gauze on Primary Bleeding Cessation After Molar Extraction — 17; 12; 4; 10 Participants

Primary: Sum of Pain Intensity Difference From 0 to 24 Hours (SPID24) Based on the 11 Point Numeric Pain Rating Scale — -96.80; -100.69; -74.96 score on a scale — p=0.0258