N/A N=600 Timing of Dietary Acid Intake, Brushing Teeth and Acid Erosion.
Tooth Wear
Primary: Basic Erosive Wear Examination — 15.01; 6.27 Units on a scale — p=<0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=17 Retrospective Clinical Evaluation of Nano-hybrid-composite Denture Teeth
Edentulous Mouth · Dental Prosthesis Failure
Primary: Survival Rate of Dentures With SR Phonares II Teeth — 17 Participants
N/A N=135 Evaluate the Effectiveness of an Experimental Urethane Dimethacrylate Resin Based Dental Composite Material
Dental Caries · Restorative Material
Primary: Percent of Teeth With Anatomic Form Graded as A or B. — 42; 37; 40; 2 teeth — p=0.2552
Phase 3 N=626 The Efficacy of a Toothpaste to Reduce Sensitivity
Dentin Hypersensitivity
Primary: Hypersensitivity Tactile(Yeaple Probe) — 19.81; 13.94 units on a scale — p=0.05
N/A N=79 Clinical Efficacy of a Toothpaste on Hypersensitivity Reduction
Hypersensitivity
Primary: Tooth Hypersensitity to Touch Stimuli (Tactile) — 10.83; 10.63 Units on a scale — p=0.05
N/A N=36 In Vivo Assessment of the Tooth-Resin Composite Interface Using Optical Coherence Tomography
Cavity · Cavities of Teeth
Primary: Marginal Staining: World Dental Federation (FDI) Criteria - Baseline — 18; 18; 0; 0 Participants
Phase 3 N=62 In Situ Erosion Study to Investigate the Effectiveness of an Experimental Toothpaste
Tooth Erosion
Primary: % Surface Micro Hardness Recovery (SMHR; Comparison of 1150 Ppm Fluoride and 5% KNO3 Dentifrice Relative to a Fluoride Free Placebo Dentifrice to Enhance…
N/A N=56 Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental Erosion
Dental Erosion · Acid Wear
Primary: Relative Erosion Resistance (RER) of Enamel Specimens Post 4 Hours of Treatment Exposure — -36.66; -36.53; -36.98; -77.82 Percentage RER — p=<0.0001
Phase 2 N=36 Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion
Tooth Erosion
Primary: Adjusted Mean Percent Net Erosion Resistance (NER) of Enamel Specimens Exposed to Test Dentifrice + Test MR Relative to: 1) Test Dentifrice+ Sterile Water Rinse 2)…
N/A N=33 An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel
Tooth Erosion
Primary: Adjusted Mean Percent Surface Microhardness Recovery (%SMHR) at 4 Hours (Test Dentifrice Versus (vs.) Placebo Control Dentifrice) — 32.20; 23.85 percent SMHR — p=0.0012
N/A N=45 Efficacy of Three Toothpastes Using an in Situ Caries Model
Dental Caries
Primary: Percentage Surface Microhardness Recovery (SMHR) of Phyte (0% 0.425% and 0.85%) at 2 Weeks — 25.53; 26.81; 7.41; 28.88 % SMHR — p=0.7603
N/A N=86 Clinical Evaluation of an Experimental Remineralization Product
White Spot Lesion
Primary: White Spot Measurement — 34; 37; 1; 0 Lesions
N/A N=15 Remineralization of Molar Incisor Hypomineralization (MIH) With a Hydroxyapatite Toothpaste
Molar Incisor Hypomineralization
Primary: Change in Mineral Density (MD) of Tooth — 26.02; 14.64; 29.26; 16.83 percentage of remineralization
N/A N=30 In Vivo Investigation of Initial Stages of Enamel Erosion
Tooth Erosion
Primary: Change From Pre-acid Challenge (Baseline) Tooth Impression Grading Score Immediately Following an Acid Challenge — 3.75; 3.17 Scores on grading scale — p=0.2673
N/A N=50 Nobio Clinical Study - Demineralization Prevention With a New Antibacterial Restorative Composite
Dental Caries · Denture, Partial, Removable
Primary: Mineral Loss ΔZ — 235; 774 vol% * μm]
Phase 4 N=40 MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study
Dental White Spots · Dental Caries
Primary: Change in White Spot Lesions Count - Enamel Decalcification Index (EDI) — 40.2; 41.3 units on a scale
N/A N=38 Assessing Effects of a Denture Gel on Gum Abrasions
Gum Injury
Primary: Abrasion Assessment (Number) — 3.65; 4.11 number of abrasions
Phase 4 N=65 Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride
Dental Caries
Primary: Percentage Surface Micro Hardness Recovery (% SMH), of Brushing for 2 Minutes Versus (vs.) Brushing for 45 Seconds With 1.5g of Experimental Dentifrice. — 41.61; 34.66 %…
N/A N=120 Clinical Evaluation of Enamel Microhardness Using Tooth Whitening Agents
Dental Atraumatic Restorative Treatment
Primary: Enamel Hardness — 348.4; 351.6; 354.5 Vickers hardness kg f/mm2 — p=0.231
N/A N=53 Use of Two Dissolvable Therapeutics Under Removable Partial Dentures
Edentulous Jaw · Edentulous Mouth
Primary: Change From Baseline in Patient Comfort for as Assessed by Numerical Scale. — 0.99; 1.16 units on a scale
N/A N=62 The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ
Oral Hygiene
Primary: Percentage Surface Microhardness Recovery (% SMHR) — 32.49; 31.81; 27.56; 22.62 Percentage of SMHR — p=<0.0001
N/A N=38 Fluoride Varnish for Treatment of White Spot Lesions
White Spot Lesions
Primary: DIAGNOdent Readings at Baseline, Three and Six Months - Intergroup Comparison — 5.10; 6.01; 4.08; 5.50 units on a scale — p=0.636
Phase 3 N=113 Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Day 14 — -1.20; -0.37 Score on a scale — p=<0.0001
N/A N=230 The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline in Schiff Sensitivity Score on Day 3 — -0.96; -0.77 Score on a scale — p=0.1575
N/A N=263 A Study to Measure the Efficacy of a Toothpaste on Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Thermo-evaporative (Schiff Air Blast) Stimuli — 2.188; 2.246; 1.268; 1.811 score on a scale — p=<0.001
N/A N=60 Survival of Endocrowns Made From Different Ceramics
Pulp Disease, Dental · Dental Caries · Dental Leakage
Primary: Survival of Dental Prosthesis — 19; 14; 17 Teeth
Phase 3 N=65 In Situ Caries Model of Fluoride Toothpastes
Caries
Primary: Percent Surface Microhardness (SMH) Recovery of Enamel Specimens Exposed to NaF Toothpaste (1426ppmF) and AmF Toothpaste (1400ppmF) — 38.05; 41.06 Percentage SMHR…
Phase 2 N=20 Experimental Dentifrice Remineralization/Fluoride Uptake in an in Situ Model
Dental Erosion
Primary: Percentage Surface Micro-hardness Recovery (SMHR) of Enamel Specimens — 39.46; 38.31; 36.17; 17.26 % SMHR — p=0.7756
N/A N=279 Clinical Study to Investigate the Tooth Stain Removal Efficacy of Two Experimental Toothpastes Compared to a Standard Toothpaste When Used Twice Daily for 8 Weeks
Oral Hygiene
Primary: Change From Baseline in Mean Total Modified Lobene Stain Index (MLSI) Score at Week 8 — -2.33; -2.42; -0.38 score on a scale — p=<0.0001
N/A N=29 Intra Oral Kinetics of Fluoride Containing Dentifrices
Tooth Erosion
Primary: Concentrations of Fluoride Ions in Saliva 60 Minutes Post Brushing Prior to Administration of the Orange Juice or De-ionised Water Rinse — 0.23; 0.23; 0.15 parts per…