N/A N=99 Time-dependent Improvement of Functional Outcome Following Oxford Medial Unicondylar Knee Replacement
Osteoarthritis
Primary: Knee Injury and Osteoarthritis Outcome Score — 85.5; 88.2 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=80 Knee Bracing for People With Patellofemoral Osteoarthritis
Knee Osteoarthritis
Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline
N/A N=51 Efficacy Study of an Unloading Brace for Knee Osteoarthritis
Osteoarthritis of the Knee
Primary: Knee Injury and Osteoarthritis Outcome Score (KOOS) Pain Score — 2.92; 2.86; 3.03; 2.67 units on a scale — p=<0.05
N/A N=23 In Vivo Three-Dimensional Determination of Osteoarthritis Brace Effectiveness
Osteoarthritis, Knee
Primary: Medial Condylar Separation With Brace — 0.60 mm
N/A N=27 Muscle Weakness and Post-traumatic Knee OA
Meniscectomy
Primary: Change in International Knee Documentation Committee (IKDC) Subjective Knee Form Score — 22.2; 20.6 units on a scale
Phase 2 N=389 A Study to Evaluate the Safety and Efficacy of Topically Applied TV-45070 (Ointment) in Participants With Primary Osteoarthritis (OA) Affecting a Single Knee
Osteoarthritis of the Knee
Primary: Change From Baseline to Last 5 Days of Treatment in the Average Evening Pain Intensity In the Target Knee When Walking on a Flat Surface Using a Mixed Model for Repeated…
Phase 2 N=157 Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee
Osteoarthritis, Knee
Primary: Change From Baseline in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Domain Score at Week 2 — -3.64; -3.15 Units on a scale — p=0.39
Phase 3 N=56 Intra-Articular Injections of Platelet-Rich Plasma in Knee Osteoarthritis: Unique Application Versus Triple Application
Osteoarthritis
Primary: Change in the Western Ontario and McMaster Universities (WOMAC) Ostearthritis Index (Therapeutic Effect) — 28.53; 22.27 units on a scale
Phase 4 N=70 The Effect of Intra-articular Bilateral Knee Injections of Zilretta on Performance Measures in Adults With Knee OA
Knee Osteoarthritis
Primary: 30 Second Chair Standing Test — 9.5 stands
N/A N=100 Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
Osteoarthritis of the Knee
Primary: Change in KOOS4 From Baseline (Knee Injury and Osteoarthritis Outcome Score) — 16.0; 32.5 units on a scale
N/A N=10 A Biologic Joint Replacement Strategy to Treat Patients With Severe Knee Trauma and Post-Traumatic Knee Osteoarthritis
Post-traumatic Osteoarthritis
Primary: Visual Analogue Scale Pain Score — 2.3 units on a scale
N/A N=79 Gait Modification Treatment for Knee Osteoarthritis
Knee Osteoarthritis
Primary: Change From Baseline to Week 17 and From Baseline to Week 21 in Pain as Measured by Numerical Rating Scale — -2.1; -1.8; -2.2; -1.5 units on a scale — p=0.495
N/A N=40 Muscle Property, Alignment and Joint Loading in People With Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change of External Knee Adduction Moment as Assessed by Visual Motion Analysis System — 0.50 Nm/kg
Phase 2 N=183 A Study to Assess the Safety and Efficacy of a Single Dose of UBX0101 in Patients With Osteoarthritis of the Knee
Osteoarthritis, Knee
Primary: Change From Baseline to Week 12 of the Western Ontario and McMaster Universities Osteoarthritis Index Pain Subscale (WOMAC-A) Score in Patients Receiving a Single Dose…
N/A N=76 Home Rehabilitation in Patients After Primary Total Knee Arthroplasty
Osteoarthritis · Rehabilitation
Primary: Total WOMAC Score — 51.64285714; 52.47619048; 39.60714286; 40.38095238 score on a scale
N/A N=45 The Assessment of Patient Specific Instrumentation for Unicompartmental Knee Replacement
Knee Arthritis
Primary: Radiological Assessment of Component Positioning — 0.9; 1.8; 9.1; 8.8 Degrees — p=<0.05
N/A N=47 Cemented Versus Cementless Unicompartmental Knee Arthroplasty
Osteoarthritis, Knee
Primary: Radiostereometric Analysis Examination - Translations — -0.01; 0.05; -0.10; -0.17 millimetres
N/A N=14 Spring Loaded Tri-Compartment Unloader Knee Brace Study
Anterior Knee Pain
Primary: Knee Injury and Osteoarthritis Outcome Score (KOOS) — 61.91; 72.59; 71.17; 85.99 score on a scale
N/A N=162 Calypso Knee System Clinical Study, OUS
Osteoarthritis, Knee
Primary: Percentage of Participants With Composite Clinical Success (CCS) — 83.5; 57.2 percentage of subjects
N/A N=144 Intra-articular Polyacrylamide Hydrogel in Knee Osteoarthritis
Osteoarthritis
Primary: Change of the Total WOMAC Score (WOMAC-T) — -624.12; -444.82; -605.61; -426.31 score on a scale — p=0.00030
N/A N=57 Intra-articular Polyacrylamide Hydrogel in the Treatment of Knee Osteoarthritis
Osteoarthritis, Knee
Primary: Change in the Total WOMAC Score (WOMAC-T) — 1137.13; 767.47; 1271.60; 445.33 score on a scale — p=0.00
N/A N=100 Structured Non-operative Treatment of Knee Osteoarthritis
Osteoarthritis of the Knee
Primary: Change From Baseline in KOOS4 (Knee Injury and Osteoarthritis Outcome Score) — 18.2; 7.1 units on a scale
N/A N=3,000 Development of an Osteoarthritis (OA) Care Plan to Improve Process and Quality of OA Treatment Decisions
Osteo Arthritis Knee · Osteoarthritis, Hip
Primary: Differences in Decision Conflict Scale With ASK vs Usual Care — 25.1; 26.0 Score on a scale
N/A N=80 Trial of Realignment Therapy for Treatment of Medial Knee Osteoarthritis
Knee Osteoarthritis
Primary: Mean Change WOMAC Pain Scale (Most Symptomatic Treated Knee) — -2.2; -1.7 units on a scale change from baseline
N/A N=65 Intra-articular Polyacrylamide Hydrogel in Gonarthrosis
Osteoarthritis
Primary: Change in the Total WOMAC Score (WOMAC-T) — 649.80; 1091.70; 767.47; 293.60 score on a scale — p=0.004
N/A N=93 Wearable LITUS Device for Osteoarthritis of the Knee: a Randomized Double-Blind Placebo-Controlled Trial
Knee Osteoarthritis
Primary: Pain on the Numeric Rating Scale (NRS) Change From Baseline to Study Conclusion — -1.96; -0.85 units on a scale
N/A N=64 Needling Techniques for Knee Osteoarthritis
Knee Osteoarthritis · Kidney Yin Deficiency · Kidney Yang Deficiency
Primary: WOMAC Total in Week 15 — 11.6; 54.4 score on a scale — p=<0.001
Phase 3 N=164 A Study on Visco-antalgic Intra-articular Administration in Symptomatic Knee Osteoarthritis
Knee Osteoarthritis
Primary: Change From Baseline in WOMAC VA3.1 Pain Subscale Score at Month 6 — -23.6; -14.1 mm — p=0.141
Phase 3 N=231 Duloxetine Versus Placebo for Osteoarthritis Knee Pain
Osteoarthritis Knee Pain
Primary: Weekly Change From Baseline in the 24-Hour Average Pain Rating Using an 11-Point Numerical Likert Scale Patient Diary — -0.36; -0.84; -0.95; -1.54 units on a scale…
N/A N=1,261 Survey of Osteoarthritis Real World Therapies (MK-0663-140)
Osteoarthritis
Primary: Percentage of Participants Who Reported Adequate vs. Inadequate Pain Relief at Baseline — 46.2; 53.8 Percentage of Participants