A systematic review looked at how certain natural compounds might affect the immune system in people with chronic rhinosinusitis (CRS). The researchers focused on substances such as epigallocatechin-3-gallate, curcumin, rosmarinic acid, bromelain, and cineole. These ingredients are often studied for their anti-inflammatory properties.
The review found that these natural products may work by targeting specific pathways in the body. For example, they might help regulate immune cells that control inflammation. Specifically, some evidence suggests that bromelain and cineole have shown clinical effectiveness in treating acute sinusitis cases.
Because this was a review of existing research, the results are not yet definitive for all types of treatment. Some compounds only have evidence for acute cases rather than long-term chronic conditions. You should talk to your doctor before starting any new supplements to ensure they are safe and appropriate for your specific health needs.
