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Surgical removal of an ectopic tooth and associated cyst resolves symptoms of unilateral sinusitisSurgical removal of dental cyst resolves persistent sinus infection

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Key Takeaway
Consider ectopic maxillary third molars with associated cysts as a potential cause for persistent unilateral sinus symptoms.

This case report describes a 24-year-old female presenting with purulent nasal discharge and facial swelling. The clinical presentation was linked to an ectopic maxillary third molar associated with an odontogenic keratocyst. The patient underwent surgical removal of the ectopic tooth and complete excision of the cyst via an intraoral approach under general anesthesia.

Following the procedure, symptoms completely resolved. A postoperative CBCT review at 6 months showed good pneumatization of the right maxillary sinus without signs of recurrence. These findings suggest that surgical intervention is effective for resolving localized infection caused by dental-related cysts.

Due to the nature of this report as a single case study, the results cannot be generalized to a broader population. The evidence level is low because it lacks a larger cohort or comparative data. However, it highlights the importance of considering ectopic teeth and associated cysts in patients with persistent unilateral sinus symptoms that do not respond to medical treatment.

How this fits prior evidence

This case report addresses a gap in identifying specific dental causes for localized sinusitis. While prior coverage noted natural anti-inflammatory products may modulate immune pathways like JAK-STAT and Th17 in rhinosinusitis, this case highlights how mechanical obstruction or infection from an odontogenic keratocyst can cause similar symptoms. It provides a specific clinical scenario where surgical intervention is required rather than medical management.

Imagine dealing with a constant sinus infection that just won't go away despite medical treatment. For one 24-year-old woman, the source of her pain and facial swelling was not just a standard infection. It was actually caused by an odontogenic keratocyst, which is a type of cyst that forms in the jawbone near a misplaced tooth.

Doctors performed surgery to remove both the extra tooth and the entire cyst under general anesthesia. Following the procedure, her symptoms completely resolved. A follow-up scan six months later showed that her sinus was healing well with no signs of the cyst coming back.

Because this report focuses on just one patient, we cannot say for certain how common this specific cause is for everyone. However, it highlights an important clue: if a person has a persistent infection on only one side of the face that does not respond to medicine, doctors should look closely at the jaw and teeth using imaging scans.

What this means for you:
Surgery to remove a cyst near a misplaced tooth can resolve persistent sinus infections and facial swelling.

Common questions

What caused the woman's facial swelling and sinus issues?

The woman had a condition called an odontogenic keratocyst. This is a type of cyst that formed in her jaw near an ectopic, or misplaced, tooth. The presence of this cyst led to purulent nasal discharge and facial swelling.

How was the condition treated?

The patient underwent surgery under general anesthesia. Surgeons used an intraoral approach to perform a complete excision of the cyst and remove the ectopic tooth. This procedure successfully resolved her symptoms.

What did the follow-up scans show?

A CBCT scan performed six months after surgery showed good pneumatization of the right maxillary sinus. This means the sinus was filling with air as expected, and there were no signs that the cyst was returning.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedJul 2026
View Original Abstract ↓
Ectopic teeth in the maxillary sinus are relatively rare, most commonly seen in the third molars, often accompanied by odontogenic cysts and presenting with symptoms similar to chronic sinusitis, which are easily misdiagnosed or overlooked. A 24-year-old female patient presented with purulent nasal discharge and recurrent swelling of the right side of the face for 2 years. Despite multiple courses of antibiotic treatment, her symptoms showed little improvement. Clinical examination revealed the absence of the right maxillary third molar. Panoramic x-ray showed a tooth-like high-density shadow in the right maxillary sinus, surrounded by soft tissue density. Cone beam computed tomography (CBCT) further confirmed the presence of an ectopic third molar in the right maxillary sinus, accompanied by a cystic lesion. The patient underwent surgical removal of the ectopic tooth and complete excision of the cyst under general anesthesia via an intraoral approach. Postoperative histopathological examination confirmed the diagnosis of odontogenic keratocyst. The patient's symptoms completely resolved after surgery, and a 6-month postoperative CBCT review showed good pneumatization of the right maxillary sinus with no signs of recurrence. For persistent unilateral sinus symptoms that are unresponsive to conventional medical treatment, the presence of an ectopic maxillary third molar with an odontogenic cyst should be considered. Good clinical outcomes can be achieved by surgically removing the ectopic tooth and the associated cyst. This case also suggests that when tooth eruption is abnormal, early imaging evaluation is of significant value.
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