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Whole health team intervention reduced pain interference by 0.58 points versus cognitive behavioral therapy in VA patientsA new team approach offers small but real relief for chronic pain in VA patients

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Key Takeaway
Consider whole health team intervention for small, significant improvement in pain interference versus cognitive behavioral therapy.

This randomized clinical trial evaluated the efficacy of a whole health team intervention for patients with chronic pain. The study population consisted of 764 patients receiving primary care within six Veterans Affairs health systems in the US. Participants were assigned to one of three groups: the whole health team intervention, cognitive behavioral therapy delivered in group sessions, or usual care. The primary outcome measured was the Brief Pain Inventory interference subscale score at 12 months. The follow-up period for the study was 12.0 months.

The whole health team intervention group demonstrated a mean BPI-I subscale score of 4.9 at 12 months, an improvement from a baseline of 6.6. The cognitive behavioral therapy group improved from a baseline of 6.4 to a mean score of 5.5 at 12 months. The usual care group improved from a baseline of 6.4 to a mean score of 5.7 at 12 months. All groups showed some degree of improvement in pain interference scores over the study period.

When comparing the whole health team intervention to cognitive behavioral therapy, the mean difference in BPI-I scores was -0.58. The 97% confidence interval for this difference ranged from -1.11 to -0.05. The p-value was not reported in the provided data. This difference was statistically significant. When comparing the whole health team intervention to usual care, the mean difference was -0.77. The 99% confidence interval for this comparison ranged from -1.40 to -0.15.

In contrast, cognitive behavioral therapy did not improve pain interference scores significantly more than usual care. The mean difference between these two groups was -0.19. The 99% confidence interval for this difference ranged from -0.89 to 0.50. This interval included zero, indicating no statistically significant difference between the cognitive behavioral therapy and usual care groups.

Safety data reported suicidal ideation rates across the study groups. Suicidal ideation occurred in 15.9% of patients in the cognitive behavioral therapy group. The rate was 13.7% in the whole health team group and 13.4% in the usual care group. Serious adverse events were not reported. Discontinuations due to adverse events were not reported. Tolerability details were not reported.

The results support the use of the whole health team approach to attain a statistically significant but small improvement in pain interference in VA patients with chronic pain. The absolute magnitude of the improvement between the whole health team and cognitive behavioral therapy was modest. The confidence intervals for the primary comparisons did not cross zero, confirming statistical significance. However, the clinical relevance of a 0.58 point difference on the BPI-I subscale requires careful interpretation by clinicians.

Limitations of the study include the lack of reported funding or conflicts of interest. The study phase was not reported. The publication type was not reported. Causality was not explicitly reported. These factors suggest caution when generalizing findings to other settings or populations. The study was conducted exclusively within VA health systems, which may limit applicability to non-VA settings.

Future research should investigate whether the whole health team intervention offers advantages over cognitive behavioral therapy in terms of cost, accessibility, or patient preference. The higher rate of suicidal ideation in the cognitive behavioral therapy group warrants attention, though the difference between groups was not statistically significant based on the provided data. Clinicians should consider these findings when selecting pain management strategies for veterans with chronic pain.

Chronic pain changes lives. It stops people from working, playing with their kids, or sleeping at night. For many patients in the US Veterans Health Administration, this pain is a daily struggle. A new study looks at whether a specific team approach can help these patients feel better. The results show a small but important improvement for those who received the new care plan.

The researchers looked at 764 patients. These people were already getting care at six different VA health systems across the country. They all had chronic pain and were receiving primary care. The team split these patients into three groups to see how different treatments worked over a year.

One group received a whole health team intervention. This means a team of doctors and staff worked together to treat the patient. Another group received cognitive behavioral therapy. This is a type of group counseling that helps people manage pain through thinking and behavior changes. The third group received usual care, which is the standard treatment they normally get.

The main measure was how much pain stopped people from doing their daily lives. This is called pain interference. At the start, the whole health team group had a score of 6.6. By the end of the year, that score dropped to 4.9. The group doing cognitive behavioral therapy started at 6.4 and ended at 5.5. The usual care group started at 6.4 and ended at 5.7. Lower scores mean less pain interference.

The whole health team approach worked better than the other two options. It led to a statistically significant improvement compared to both the group therapy and usual care. However, the improvement was small. The difference between the whole health team and the group therapy was very slight. The difference between the whole health team and usual care was also small but still real.

Safety was also checked during the study. Some patients thought about suicide. This happened in 15.9% of the group doing cognitive behavioral therapy. It happened in 13.7% of the whole health team group. It happened in 13.4% of the usual care group. The study did not report any serious adverse events or reasons for patients to stop the treatment early.

People should not overreact to these numbers. The improvement was real but small. This single study does not prove the treatment works for everyone. It only shows results for patients in the VA system. Patients should talk to their doctors about what fits their specific situation. This study supports using the whole health team approach to get a small boost in managing pain.

What this means for you:
A team approach offers small but real relief for chronic pain in VA patients compared to standard care.

Study Details

Study typeRct
EvidenceLevel 2
Follow-up12.0 mo
PublishedMay 2026
View Original Abstract ↓
IMPORTANCE: The US Department of Veterans Affairs (VA) Whole Health approach was congressionally mandated in 2016 for patients with chronic pain receiving care in VA hospitals, but no randomized clinical trials have tested its benefits. OBJECTIVE: To evaluate the effectiveness of a whole health team intervention in VA patients with chronic pain compared with cognitive behavioral therapy and with usual care, and to evaluate the effectiveness of cognitive behavioral therapy compared with usual care in reducing long-term pain interference. DESIGN, SETTING, AND PARTICIPANTS: This randomized clinical trial involving 6 VA health systems in the US enrolled participants between September 18, 2020, and January 19, 2024. Final follow-up occurred on January 27, 2025. Analyses took place between April 1, 2025, and February 3, 2026. Participants were patients with chronic pain receiving VA primary care. INTERVENTIONS: Patients with chronic pain were randomized (11:11:2) to receive a whole health team intervention (n = 343), cognitive behavioral therapy for chronic pain delivered in group sessions (n = 339), or usual care (n = 82) for 12 months. The whole health team included a primary physician or nurse practitioner, a second clinician providing nonpharmacological or integrative pain care, and a coach. The team provided interdisciplinary, individualized care consistent with the VA Whole Health model to attain personal health goals aligned with patients' personal values and life goals. MAIN OUTCOMES AND MEASURES: The primary outcome was the Brief Pain Inventory interference (BPI-I) subscale score (range, 0-10 points; higher scores indicate worse interference from pain; minimal clinically important difference, 1.0) at 12 months. RESULTS: Of 764 randomized patients (mean [SD] age, 60.5 [12.3] years; 66.5% were men), 632 (82.7%) completed 12-month follow-up. At 12 months, the whole health group had significantly improved pain interference scores (from 6.6 to 4.9) compared with the cognitive behavioral therapy (from 6.4 to 5.5) (mean difference, -0.58 [97% CI, -1.11 to -0.05]; P = .02) and usual care (from 6.4 to 5.7) (mean difference, -0.77 [99% CI, -1.40 to -0.15]; P = .002) groups. At 12 months, cognitive behavioral therapy did not improve pain interference scores significantly more than usual care (mean difference, -0.19 [99% CI, -0.89 to 0.50]; P = .46). The most common adverse event was suicidal ideation, which occurred in 15.9% of patients in the cognitive behavioral therapy group, 13.7% in the whole health team group, and 13.4% in the usual care group. CONCLUSIONS AND RELEVANCE: These results support use of the whole health team approach to attain a statistically significant but small improvement in pain interference in VA patients with chronic pain. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04330365.
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