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Continuous brachial plexus block reduces pain at rest following elective shoulder surgeryContinuous nerve blocks may lower pain after shoulder surgery

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Key Takeaway
Consider continuous brachial plexus blocks for reduced pain at rest, but note that evidence for dynamic pain is not significant.

This meta-analysis evaluated the efficacy of continuous brachial plexus blocks compared to single-injection brachial plexus blocks in 1198 adult patients undergoing elective shoulder surgery. The study aimed to assess patient-reported pain intensity and other clinical outcomes during the immediate postoperative period. The primary outcome was measured as patient-reported pain intensity at rest and during movement at 12h, 24h, and 48h post-surgery.

The primary outcome analysis revealed statistically significant improvements in pain at rest for patients receiving the continuous brachial plexus block. At 12h post-surgery, the continuous block group reported lower pain at rest with an effect size of -1.96 (95% CI -2.81 to -1.11, p < 0.001). This trend continued at 24h, where the effect size was -1.66 (95% CI -2.27 to -1.05, p < 0.001). At 48h post-surgery, the continuous block group still demonstrated lower pain at rest with an effect size of -1.18 (95% CI -1.84 to -0.53, p < 0.001).

In contrast, the primary outcome of pain during movement did not reach statistical significance for either time point. At 24h, the effect size for pain on movement was -2.04, but the result was not statistically significant (95% CI -4.26 to 0.19, p = 0.07). Similarly, at 48h, the effect size for pain on movement was -1.30, which was also not statistically significant (95% CI -3.67 to 1.07, p = 0.28).

Secondary outcomes included the assessment of nausea and vomiting, sleep quality, patient satisfaction, opioid requests, and functional scores. While these factors are critical for postoperative management, specific numerical data for these secondary outcomes were not reported. Safety and tolerability data, including specific adverse event rates or serious adverse events, were not reported in the analysis.

These results suggest that continuous brachial plexus blocks are associated with better pain at rest and other patient-centered outcomes following shoulder surgery compared to single-injection techniques. However, the lack of statistical significance in pain during movement suggests that the superiority of continuous blocks for dynamic pain is not established by this data. These findings should be weighed against the clinical requirements of the specific shoulder procedure being performed.

Methodological limitations include the fact that the effects on dynamic pain and long-term functional recovery remain uncertain. The lack of reported safety data and specific secondary outcome values limits the ability to fully assess the clinical profile of continuous blocks. Furthermore, the absence of reported follow-up duration limits the ability to assess late-stage recovery. Questions remain regarding the specific duration of the continuous block and the specific types of shoulder surgeries included in the meta-analysis.

Recovering from shoulder surgery can be a grueling experience. For many patients, the primary concern is managing intense pain while the body heals. When pain is severe, it can make it hard to rest, sleep, or begin the early stages of physical therapy. Doctors often use nerve blocks, which are injections of medicine near the nerves, to numb the area and provide relief. This research looks at how different methods of delivering that medicine might change the experience for patients undergoing elective shoulder procedures.

The researchers looked at data from nearly 1,200 adult patients who underwent elective shoulder surgery. They compared two different methods of nerve blocks. The first method was a continuous brachial plexus block, where medicine is delivered steadily. The second method was a single-injection brachial plexus block. The goal was to see which method did a better job of controlling pain during the first two days after surgery.

The results showed that patients who received the continuous block reported significantly less pain while resting at the 12, 24, and 48-hour marks after their surgery. This means that for the first two days, the steady flow of medicine was more effective at keeping pain low during quiet moments. However, the researchers did not find a statistically significant difference between the two methods when it came to pain during movement at both 24 and 48 hours. While the continuous block helped with resting pain, it did not show a clear advantage for pain caused by moving the arm in this specific study.

It is important to keep these findings in perspective. While the results are promising for pain management at rest, the study has some limitations. Specifically, the researchers noted that the effects on dynamic pain—pain that happens when you move—and long-term recovery of function are still not fully known. Because this is a meta-analysis, it combines data from multiple sources to find a general trend, but it does not mean every patient will have the exact same experience. For patients right now, this means that a continuous nerve block is a promising option for managing the initial, heavy pain of recovery after shoulder surgery. It may help patients feel more comfortable while resting in the days immediately following their procedure. However, because the impact on movement-related pain and long-term recovery is still uncertain, patients should talk to their surgical team about which specific nerve block method is best for their individual goals and recovery plan.

What this means for you:
Continuous nerve blocks may provide better pain relief at rest for patients in the first 48 hours after shoulder surgery.

Study Details

Study typeMeta analysis
Sample sizen = 1,198
EvidenceLevel 1
PublishedOct 2026
View Original Abstract ↓
INTRODUCTION: Single-injection and continuous brachial plexus block techniques are used widely for postoperative analgesia in patients undergoing shoulder surgery. Although patient-reported outcomes are described in individual studies, their effects have not been synthesised comprehensively using a patient-centred framework. We sought to compare the effects of single-injection vs. continuous brachial plexus block techniques on patient-reported outcomes in adult patients following elective shoulder surgery. METHODS: Databases were searched from inception to October 2025 and randomised controlled trials reporting patient-reported outcomes were included. Co-primary outcomes were postoperative patient-reported pain intensity at rest and during movement at 12 h, 24 h and 48 h post-surgery. Secondary outcomes included nausea and vomiting; sleep quality; patient satisfaction; opioid requests; and functional scores. Random-effects meta-analysis and trial sequential analysis were performed, with risk of bias and quality of patient-reported outcome reporting assessed. RESULTS: Twenty randomised controlled trials that included 1198 patients were analysed. Continuous brachial plexus blocks were associated with lower pain at rest at 12 h, 24 h and 48 h, with mean differences (MD) of -1.96 (95%CI -2.81 to -1.11, p < 0.001), -1.66 (95%CI -2.27 to -1.05, p < 0.001) and - 1.18 (95%CI -1.84 to -0.53, p < 0.001), respectively. Pain on movement could only be pooled at 24 h and 48 h and showed MD -2.04 (95%CI -4.26-0.19, p = 0.07) and - 1.30 (95%CI -3.67-1.07, p = 0.28) respectively. The co-primary outcomes approached or exceeded the predefined minimal clinically important difference for pain scores after shoulder surgery, in favour of continuous techniques. DISCUSSION: Continuous brachial plexus blocks are associated with better pain at rest and other patient-centred outcomes following shoulder surgery, while effects on dynamic pain and long-term functional recovery remain uncertain.
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