Researchers conducted a randomized controlled trial in Uganda to see if specific support methods could improve PrEP adherence. The study included 200 HIV-negative transgender women. One group received drug-level feedback and tailored counseling, while the other group received standard care. The study tracked medication levels in urine and blood spots over 12 months.
The results showed that while the counseling and feedback were feasible, they did not actually improve the rate of PrEP adherence compared to standard care. However, researchers did find that other factors, such as higher monthly income, a history of taking daily medication, and not being harassed by police, were linked to better adherence.
Because the study found no significant improvement from the specific counseling intervention, it suggests that other factors may play a larger role in how well patients stay on their medication. Patients should talk to their healthcare providers to discuss the best ways to manage their specific treatment plans.
