HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Drug Pipeline
Cohort
Switching from EFV/TDF/3TC to B/F/TAF or DTG/3TC in virologically suppressed PLWH shows no significant between-group metabolic differences over 24 months.
Switching HIV drugs showed similar metabolic changes over two years in this real-world study.
This retrospective real-world study evaluated 326 virologically suppressed persons with HIV (PLWH) switching from efavirenz/tenofovir disopr…
Switching HIV drugs caused similar weight gain and metabolic shifts over two years, meaning lifestyle factors matter more than the specific …
Frontiers
Apr 18, 2026
Infectious Disease
Meta-analysis
Cochrane review: injectable lenacapavir cuts HIV infections versus oral PrEP at 52 weeks
One Shot Saves You From HIV For Six Months
This Cochrane systematic review and meta-analysis of two randomised controlled trials (8660 participants) compared six-monthly subcutaneous …
A single shot under the skin protects against HIV for six months, solving the daily pill problem for millions at risk.
Apr 15, 2026
Infectious Disease
CDC updates recommendations for HIV nonoccupational postexposure prophylaxis
CDC updates recommendations for HIV prevention medication after possible exposure
The CDC has issued updated recommendations for antiretroviral postexposure prophylaxis following nonoccupational HIV exposure. The guidance …
The CDC updated its guidance on taking HIV prevention medication after a possible exposure to help doctors give the most current advice.
CDC
Apr 4, 2026
Allergy & Immunology
Phase III
Phase 3 trial compares switch to doravirine/islatravir versus continuing bictegravir/FTC/TAF in HIV-1
Phase 3 trial compares two HIV drug regimens for people already virologically suppressed.
A phase 3 randomized controlled trial enrolled 643 virologically suppressed adults with HIV-1 to compare switching to doravirine/islatravir …
People with HIV already on effective treatment can safely switch to a new two-drug pill without losing virus control, according to a complet…
CT.gov
Apr 2, 2026