Brief research report on toxicity-guided TMP-SMX dose reduction in disseminated nocardiosis
Gold miner's rare infection treated with adjusted antibiotic dose
This brief research report describes a single case of disseminated nocardiosis with CNS involvement in a patient with pneumoconiosis.
A gold miner with a rare brain infection improved after doctors lowered his antibiotic dose due to severe side effects.
Meta-analysis of antimicrobial resistance prevalence in Tanzanian hospital pathogens
Common Antibiotics Are Failing in Tanzania, New Data Reveals
This systematic review and meta-analysis synthesizes data from 28 studies on antimicrobial resistance in clinically relevant pathogens withi…
This research shows that common antibiotics are losing their power in Tanzania, urging a critical update to how infections are treated.
Retrospective cohort study assesses Acinetobacter baumannii prevalence and resistance in ventilator-associated infections
ICU Infection Risk Skyrockets Without Local Drug Data
This retrospective observational cohort analyzed 3,540 non-duplicate clinical isolates from a tertiary-care ICU in South India.
ICU patients with breathing tubes face higher infection risks when doctors lack fresh local data on which antibiotics actually work against …
Retrospective study finds low resistance to key antibiotics in TB patients with UTIs
When TB Treatment Hits a Wall: The Hidden Bladder Problem
A retrospective cohort study of 1,151 bacterial strains from tuberculosis patients with urinary tract infections at a single hospital found …
Tuberculosis patients with urinary infections face drug-resistant bacteria, but a five-year hospital review reveals which antibiotics still …
ALIS plus macrolide regimen improves culture conversion in noncavitary MAC lung disease
An Inhaled Antibiotic Shifts the Odds in a Stealthy Lung Infection
In a 99-patient RCT of adults with noncavitary MAC lung disease, adding 6 months of amikacin liposome inhalation suspension (ALIS) to a macr…
Adding a nebulized antibiotic to standard pills helped more newly diagnosed MAC lung patients clear the bug sooner, with no new safety surpr…
In vitro amikacin resistance linked to kanamycin cross-resistance but not streptomycin in M. avium-intracellulare complex
Lost to Amikacin? Streptomycin Might Still Work
This single-center retrospective study evaluated cross-resistance among aminoglycosides in 20 patients with amikacin-resistant M.
When amikacin fails to treat stubborn lung infections, streptomycin often remains effective, offering hope for patients facing drug-resistan…