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Home › Medications › anakinra

anakinra

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of anakinra

27 trials tracked of anakinra: 6 in phase 3 or 4 and 3 with published results. The most-cited published study has 163 citations.

27Trials tracked
6Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 3 6 Phase 2 19 Phase 1 1 Other / NA 1
  1. Phase 3 Treatment of COVID-19 Patients With Anti-interleukin Drugs Completed · 163 cited
  2. Phase 3 Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic Hepatitis Completed · 101 cited
  3. Phase 3 MIS-C Comparative Effectiveness Study Completed · 6 cited
  4. Phase 3 Early Treatment of Cytokine Storm Syndrome in Covid-19 Completed
  5. Phase 3 The Role of Interleukin-1 Beta Targeted Therapy for Patients Suffering From Allergic Contact Dermatitis Completed
  6. Phase 3 Anakinra to Prevent Post-infarction Remodeling Completed
Show 21 more trials
  1. Phase 2 A Phase 2 Trial of Anakinra for the Prevention of CAR-T Cell Mediated Neurotoxicity Completed
  2. Phase 2 Pilot Study of the Safety and Efficacy of Anakinra (Recombinant Human Interleukin-1 Receptor Antagonist) in Heart Failure Completed
  3. Phase 2 Nutrition, Inflammation and Insulin Resistance in End Stage Renal Disease-Aim 2 Completed
  4. Phase 2 Anakinra for Behcet s Disease Completed
  5. Phase 2 Anakinra for Inflammatory Pustular Skin Diseases Completed
  6. Phase 2 Anakinra for the Reduction of CAR-T Toxicity in Patients With Relapsed or Refractory Large B-cell Lymphoma Completed
  7. Phase 2 Anti-inflammatory Therapy With Anakinra in Newly Diagnosed Type 1 Diabetes Completed
  8. Phase 2 Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple Sclerosis Completed
  9. Phase 2 Anti-Cytokine Therapy for Hemodialysis InflammatION Completed
  10. Phase 2 A Clinical Trial of Anakinra for Steroid-Resistant Autoimmune Inner Ear Disease Completed
  11. Phase 2 Interleukin-1 Blockade In Recently Decompensated Heart Failure - 2 Completed
  12. Phase 2 Interleukin-1 Receptor Antagonist for the Treatment of Heart Failure in Patients With Left Ventricular Assist Devices Completed
  13. Phase 2 CORIMUNO-ANA: Trial Evaluating Efficacy Of Anakinra In Patients With Covid-19 Infection Completed
  14. Phase 2 Anakinra as a Treatment for Hydradenitis Suppurativa Completed
  15. Phase 2 Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell Therapy Completed
  16. Phase 2 Anakinra to Prevent Adverse Post-infarction Remodeling (2) Completed
  17. Phase 2 Interleukin-1 Blockade in HF With Preserved EF Completed
  18. Phase 2 Anakinra in Infants and Children With Coronary Artery Abnormalities in Acute Kawasaki Disease Completed
  19. Phase 2 Interleukin-1 Blockade for Treatment of Cardiac Sarcoidosis Completed
  20. Phase 1 Lenalidomide and Dexamethasone With or Without Anakinra in Treating Patients With Early Stage Multiple Myeloma Completed
  21. N/A Pilot Feasibility Study of the Safety and Efficacy of Anakinra in Heart Failure With Preserved Ejection Fraction Completed

Showing the 27 most-cited and recently-updated of 27 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Randomized trial of anakinra in heart failure shows increased IL-1Ra levels versus placebo over 24 weeks
Cardiology
Randomized trial of anakinra in heart failure shows increased IL-1Ra levels versus placebo over 24 weeks Heart Failure Drug Boosts Natural Inflammation Blockers in Blood
This randomized trial abstract reports on-treatment plasma IL-1Ra levels in 63 patients with heart failure and reduced ejection fraction (HF…
A new heart failure drug significantly increases natural inflammation blockers in the blood to fight silent fires.
medRxiv Apr 26, 2026
Anakinra reduces inflammatory markers in prediabetes but shows no metabolic improvements in RCT
Diabetes & Endocrinology RCT
Anakinra reduces inflammatory markers in prediabetes but shows no metabolic improvements in RCT Two anakinra injections changed blood markers in people with prediabetes
A randomized controlled trial in individuals with prediabetes found that two injections of anakinra significantly reduced total leucocyte co…
Two anakinra injections quickly lowered inflammation markers in people with prediabetes, though the drug did not yet improve blood sugar con…
Apr 14, 2026