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Neurology
Meta-analysis
GABA-modulating pharmacotherapies show inconsistent results for improving symptoms in autism spectrum disorder
New data shows mixed results for medications targeting autism symptoms
This meta-analysis evaluated the impact of bumetanide, arbaclofen, and valproate on various symptom domains in individuals with autism spect…
Research into three specific drugs for autism shows some initial signs of improvement, but the evidence is currently too inconsistent to be …
medRxiv
Aug 25, 2026
Drug Pipeline
Phase III
Arbaclofen Phase 3 Trials Establish Clinically Meaningful Change Thresholds in Fragile X Syndrome
New Rules for Measuring Behavior Change in Fragile X
A review of two Phase 3 trials in 278 individuals with Fragile X Syndrome (aged 5-50 years) established clinically meaningful change thresho…
Imagine a parent watching their child struggle with daily routines.
Apr 24, 2026