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Pediatrics
FDA Approval
FDA Approves Crysvita (burosumab) for X-Linked Hypophosphatemia and Tumor-Induced Osteomalacia
FDA approves new drug Crysvita for rare bone diseases in children and adults.
FDA approved Crysvita (burosumab) for X-linked hypophosphatemia (XLH) in patients 6 months and older and for tumor-induced osteomalacia (TIO…
The FDA approved Crysvita (burosumab) for X-linked hypophosphatemia (XLH) and tumor-induced osteomalacia (TIO). It is the first treatment th…
FDA
Apr 29, 2026
Pediatrics
Phase II
Burosumab improves phosphate levels in 12 children and adults with fibrous dysplasia over 48 weeks.
Burosumab Restores Phosphate Balance in Rare Bone Disease
This Phase 2 trial enrolled 12 participants (7 children, 5 adults) with fibrous dysplasia to assess burosumab. At 48 weeks, 100% achieved ph…
A drug already used for rare phosphate disorders may finally offer real relief for people with fibrous dysplasia, a painful bone condition t…
Apr 27, 2026
Drug Pipeline
Substudy of Phase 3 trials: Nonfasting burosumab phosphorus levels in XLH patients remain stable after meals
Burosumab Patients May Skip Fasting Before Blood Tests
This abstract describes a substudy of Phase 3 clinical trials evaluating burosumab in adults and children with X-linked hypophosphatemia. Th…
Imagine rushing your child to a morning blood draw, stomach empty, hungry and fussy—only to find out the results might not even require fast…
Apr 24, 2026
Diabetes & Endocrinology
Sys. Review
Review examines current endocrine causes of secondary osteoporosis and clinical management approaches.
Why Normal Hormones Can Still Break Bones
This review synthesizes evidence on endocrine-related secondary osteoporosis across conditions like hypercortisolism and male hypogonadism. …
You might think strong bones only come from aging women or older men.
Frontiers
Apr 21, 2026
Diabetes & Endocrinology
Meta-analysis
Burosumab improved clinical and biochemical outcomes in patients with tumor-induced osteomalacia.
Can a new drug help patients with tumor-induced bone loss before surgery?
This hybrid study, combining a clinical survey with a systematic review, evaluated burosumab in patients with tumor-induced osteomalacia. Cl…
A new drug helps patients with tumor-induced bone loss improve health and blood chemistry while waiting for surgery or if surgery isn't poss…
Frontiers
Apr 14, 2026