CHIP mutations increase cardiovascular risk and mortality in older adults independent of traditional factors.
Your Aging Blood Cells May Be Quietly Attacking Your Heart
This review synthesizes evidence regarding clonal hematopoiesis of indeterminate potential (CHIP) in individuals older than 70 years. Findin…
Aging blood cell mutations called CHIP quietly raise heart attack risk by fueling inflammation, affecting over 10% of adults over 70.
Canakinumab shows efficacy in Japanese AOSD patients in Phase 3 open-label study
Could a monthly injection help control the painful flares of Adult-Onset Still's Disease?
A Phase 3, open-label, single-arm study evaluated canakinumab in 14 Japanese patients with Adult-Onset Still's Disease. The primary outcome …
A monthly injection helped Japanese patients with Adult-Onset Still's Disease achieve meaningful symptom relief, supporting approval for thi…