Cefmetazole or flomoxef linked to higher 14-day mortality vs carbapenems in ESBL-PE bacteremia
Trial Shows Carbapenems May Outperform Other Antibiotics for Bacteremia
This meta-analysis of 975 adults with ESBL-producing Enterobacterales bacteremia found that cefmetazole or flomoxef was associated with sign…
New data suggests carbapenem antibiotics may offer better early survival rates than cefmetazole or flomoxef for patients with specific blood…
Klebsiella pneumoniae shows 44% pooled prevalence of antibiotic resistance in Burkina Faso healthcare settings
Antibiotic-resistant Klebsiella pneumoniae found in 44% of Burkina Faso cases
This systematic review and meta-analysis evaluates the phenotypic and molecular resistance of Klebsiella pneumoniae in healthcare settings i…
A new analysis finds 44% of Klebsiella pneumoniae infections in Burkina Faso hospitals resist antibiotics, with 85% resistant to penicillin.
Newer antibiotics reduce nephrotoxicity and improve eradication of carbapenem-resistant gram-negative bacilli versus generic antibiotics in HABP/VABP
Newer antibiotics no better at preventing pneumonia deaths
This systematic review and meta-analysis evaluated newer antibiotics versus generic antibiotics for hospital-acquired and ventilator-associa…
Newer antibiotics for hospital-acquired pneumonia don't lower death risk more than older generics, but they do spare kidneys.
Meta-analysis shows carbapenems linked to higher clinical failure in OXA-48-PE infections
Doctors found higher death rates when using carbapenems for certain gut bacteria infections
This meta-analysis and review synthesizes data on carbapenem therapy for monomicrobial OXA-48-producing Enterobacterales infections. The aut…
A large review of patients with OXA-48 bacteria showed that carbapenem drugs often failed to work. Newer medicines offered better survival c…
Retrospective cohort study assesses Acinetobacter baumannii prevalence and resistance in ventilator-associated infections
ICU Infection Risk Skyrockets Without Local Drug Data
This retrospective observational cohort analyzed 3,540 non-duplicate clinical isolates from a tertiary-care ICU in South India.
ICU patients with breathing tubes face higher infection risks when doctors lack fresh local data on which antibiotics actually work against …
Retrospective cohort study links prior antibiotic exposure and Gram-negative infections to high MDR rates in adult patients with chronic liver disease
High antibiotic resistance found in infections among chronic liver disease patients in India
This retrospective observational cohort study evaluated 317 adult patients with chronic liver disease and culture-positive bacterial infecti…
In India, nearly 80% of E. coli and K. pneumoniae infections in chronic liver disease patients are resistant to multiple antibiotics.
Retrospective study finds low resistance to key antibiotics in TB patients with UTIs
When TB Treatment Hits a Wall: The Hidden Bladder Problem
A retrospective cohort study of 1,151 bacterial strains from tuberculosis patients with urinary tract infections at a single hospital found …
Tuberculosis patients with urinary infections face drug-resistant bacteria, but a five-year hospital review reveals which antibiotics still …