Washed microbiota transplantation in a malnourished child with resistant Klebsiella and Candida infections
Child’s stubborn lung infection cleared after gut bacteria transplant
This case report describes an 8-year-old boy with chronic malnutrition and multidrug-resistant pulmonary infections who received washed micr…
A gut bacteria transplant helped a severely malnourished child fight off a lung infection that antibiotics couldn’t touch.
Machine learning model predicts carbapenem-resistant Klebsiella pneumoniae risk in ICU patients
Doctors Can Now Predict Deadly ICU Infections Faster
Researchers developed a machine learning model to predict early risk of carbapenem-resistant Klebsiella pneumoniae infection in ICU patients…
Every year, thousands of ICU patients face a hidden threat: infections that resist even the strongest antibiotics.
KP ST258 Clade 2 isolates linked to increased virulence in observational and mouse studies
Klebsiella Clade 2 Linked to Worse Illness in Humans and Mice
An observational study of 172 clinical KP ST258 isolates and a mouse model found that Clade 2 isolates were associated with more acute illne…
Klebsiella pneumoniae Clade 2 causes worse illness in humans and spreads more easily to organs like the liver and spleen in mice compared to…
Carbapenem-resistant hypervirulent Klebsiella pneumoniae infection is associated with significantly higher mortality compared to carbapenem-susceptible strains in 4240 patients
Resistant superbugs kill more than 12 times as often as susceptible strains in severe infections
This systematic review and meta-analysis evaluated clinical outcomes in 4240 patients with hypervirulent Klebsiella pneumoniae (HvKp) infect…
When bacteria resists last-resort antibiotics, patients with severe infections face a 57% death risk instead of 21%.
Genomic analysis of ceftazidime/avibactam-resistant Klebsiella pneumoniae isolates from transplant unit
Italian study finds resistant bacteria in transplant unit carry multiple concerning genes
A retrospective cohort study of 14 clinical isolates from an Italian transplant unit found most ceftazidime/avibactam-resistant Klebsiella p…
Resistant bacteria in an Italian transplant unit carry multiple drug-resistance genes and traits that help them cause disease.
Research across Pneumonia
Related studies from across the Pneumonia family.
Systematic review compares viral and bacterial pathogen mechanisms in respiratory infections
Understanding how different germs hurt lungs helps doctors treat patients better and faster today
This systematic review synthesizes evidence regarding receptor recognition, cellular injury, and immunopathological mechanisms across SARS-C…
This review explains how three common germs damage human cells in unique ways. Knowing these differences helps doctors predict sickness and …
Meta-analysis shows Mycoplasma pneumoniae prevalence in children varied before, during, and after COVID-19
Mycoplasma pneumoniae infections in children rose sharply after the pandemic ended
This systematic review and meta-analysis of 70 studies examined M.
A review of 70 studies shows infection rates in kids jumped significantly after the pandemic, while rates stayed low during the outbreak.
Azithromycin to doxycycline switching in children with Mycoplasma pneumoniae pneumonia resistance gene positivity
Testing for resistance genes may guide antibiotic choices
This retrospective cohort study of 150 children with Mycoplasma pneumoniae pneumonia evaluated resistance gene expression and antibiotic man…
New evidence suggests that checking for resistance genes in children with pneumonia could help doctors decide when to switch antibiotics.
Machine Learning Algorithms Predict Plastic Bronchitis in Pediatric Mycoplasma Pneumonia Patients
Can a computer spot a deadly lung condition before it starts?
This retrospective cohort study of 307 pediatric patients with Mycoplasma pneumoniae pneumonia evaluated machine learning algorithms for pre…
A new computer program can spot a rare, life-threatening lung condition in children much earlier than current methods allow.
Macrolide-resistant Mycoplasma pneumoniae prevalence at 94% in pediatric CAP cohort
Resistant pneumonia keeps kids sicker for days
This retrospective cohort of 71 pediatric patients in China found a 94.4% prevalence of macrolide-resistant M.
In one Chinese hospital, 94% of child pneumonia cases resisted common antibiotics, leading to longer fevers and hospital stays.
Clinical indicators predict refractory Mycoplasma pneumoniae pneumonia in children
New Tool Predicts Which Kids Need Stronger Pneumonia Treatment
This retrospective case–control analysis evaluated 522 children with Mycoplasma pneumoniae pneumonia (MPP) to identify predictors of refract…
This new model gives doctors a simple way to identify children with pneumonia who might need stronger treatment right away.
Higher CRP and D-dimer levels associated with cerebral infarction in children with Mycoplasma pneumoniae pneumonia
High Fever Warning: Two Blood Tests Spot Stroke Risk in Kids
This retrospective cohort study included 2,947 children diagnosed with Mycoplasma pneumoniae pneumonia.
Two simple blood tests can spot stroke risk in kids with pneumonia before brain damage happens, helping doctors catch rare cases early.
Whole-genome sequencing of 108 CRKP isolates from South China reveals ST11 dominance and emerging hvCRKP
Genomic analysis reveals resistance patterns in carbapenem-resistant Klebsiella pneumoniae from South China hospitals
This retrospective molecular epidemiology study characterized 108 carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates from multiple h…
Genomic analysis of South China hospitals found a new KPC-12 variant in carbapenem-resistant bacteria, alongside mutations that make these g…
Review of a case report on necrotizing laryngotracheobronchitis after Mycoplasma pneumoniae pneumonia
Could a common infection trigger a rare, severe throat condition in a young boy?
This review summarizes a case report of a 7-year-old boy with necrotizing laryngotracheobronchitis following Mycoplasma pneumoniae pneumonia…
A common respiratory bug turned a seven-year-old boy's throat infection into a rare, severe condition requiring multiple airway washes to re…
PBMC gene expression profiles differentiate refractory Mycoplasma pneumoniae pneumonia in children
New Blood Test Distinguishes Severe Lung Infection Early
This cohort study of 349 children identified peripheral blood mononuclear cell gene expression profiles as potential biomarkers for refracto…
A new four-gene blood test helps doctors spot severe, hard-to-treat pneumonia in children before symptoms get too bad to fix easily.
Atopic constitution associated with severe Mycoplasma pneumoniae pneumonia in children
Why Allergy-Prone Kids Get Sicker From This Common Lung Infection
This retrospective cohort study examined 377 children with Mycoplasma pneumoniae pneumonia at Wuhan Children's Hospital.
Allergy-prone children face a higher risk of severe pneumonia from Mycoplasma, and two simple blood tests could flag who needs closer watchi…
Retrospective study links IVIG plus azithromycin to higher response rate in pediatric Mycoplasma pneumoniae pneumonia
When a Child's Pneumonia Won't Clear, This Add-On May Help
A single-center retrospective cohort of 140 children with Mycoplasma pneumoniae pneumonia found that adding intravenous immunoglobulin (IVIG…
Adding donor antibodies to standard antibiotics helped 97% of children with stubborn pneumonia recover, compared to 84% on antibiotics alone…
Questions about Klebsiella pneumoniae infection
Can a machine learning model predict the risk of my Klebsiella pneumoniae infection getting worse?
Yes, machine learning models can predict the risk of a Klebsiella pneumoniae infection becoming resistant to standard antibiotics or worsening, using data like age, blood markers, and medical history.
Full answer →Does having a transplant make my Klebsiella pneumoniae infection harder to treat with certain drugs?
Yes, having a transplant makes Klebsiella pneumoniae infections harder to treat because these patients are at higher risk for drug-resistant strains like ESBL and carbapenem-resistant Klebsiella pneumoniae (CRKP), which limit available antibiotic options.
Full answer →Why might my specific Klebsiella pneumoniae strain cause more severe illness than others?
Certain Klebsiella pneumoniae strains cause more severe illness due to specific genetic traits like hypervirulence genes (e.g., rmpA, iucA) and capsule types, which enhance resistance to immune defenses and increase spread in the body.
Full answer →