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Allergy & Immunology
Sys. Review
TNF-alpha inhibitors are the most frequent biological agents associated with de novo vitiligo development
Biological Therapies Linked to New Vitiligo Cases in Patients
This scoping review of 39 patients identifies a link between biological therapies and de novo vitiligo, most frequently involving TNF-alpha …
Some patients using biological therapies for inflammatory conditions may develop new cases of vitiligo, often appearing within months of sta…
Frontiers
Oct 6, 2026
Rheumatology
RCT
Certolizumab pegol dose escalation from 200 mg to 400 mg results in 2-fold increase in plasma concentration
Trial shows dose changes impact drug levels in rheumatoid arthritis
This post hoc analysis of a Phase III trial and open-label extension evaluated certolizumab pegol pharmacokinetics in 982 patients with acti…
New analysis shows that changing the dosage of certolizumab pegol directly affects how much medicine stays in a patient's bloodstream.
Aug 4, 2026
Rheumatology
RCT
Biological DMARDs show marginal patient-reported outcome benefits over conventional therapy in early rheumatoid arthritis
Early rheumatoid arthritis patients report similar symptom relief with different treatment approaches
This open-label randomized trial in 795 newly diagnosed, DMARD-naïve RA patients compared three biological DMARDs plus methotrexate against …
In early rheumatoid arthritis, patients reported similar pain relief and quality-of-life improvements whether they started with conventional…
Apr 9, 2026