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Home › Medications › daridorexant

daridorexant

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of daridorexant

2 trials tracked of daridorexant: 2 in phase 3 or 4 and 1 with published results. The most-cited published study has 238 citations.

2Trials tracked
2Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 1 Phase 3 1
  1. Phase 3 Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to Sleep Completed · 238 cited
  2. Phase 4 A Study to Find Out if Daridorexant is Safe and Efficacious in Patients With Insomnia and Comorbid Nocturia Completed

Showing the 2 most-cited and recently-updated of 2 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Daridorexant improves objective and subjective insomnia markers with dose-dependent efficacy across multiple trials
Drug Pipeline Meta-analysis
Daridorexant improves objective and subjective insomnia markers with dose-dependent efficacy across multiple trials New data shows daridorexant helps people with insomnia sleep better
This meta-analysis of 2905 patients found that daridorexant outperformed placebo in both objective and subjective sleep indicators for insom…
Daridorexant shows promise for treating insomnia by improving sleep time and quality, though some side effects are linked to specific doses.
Frontiers Jul 25, 2026
Daridorexant 25 or 50 mg improved sleep parameters in patients with comorbid insomnia disorder and untreated mild obstructive sleep apnoea
Drug Pipeline RCT
Daridorexant 25 or 50 mg improved sleep parameters in patients with comorbid insomnia disorder and untreated mild obstructive sleep apnoea New Hope for Sleep Without Risking Breathing
This post hoc subgroup analysis of a Phase 3 randomized clinical trial evaluated daridorexant in patients with comorbid insomnia disorder an…
You lie in bed for hours, wide awake. You’re exhausted—but your mind won’t shut off.
Apr 24, 2026