FTO-targeted strategies currently lack clinical evaluation and rely on preclinical evidence for cancer treatment
Targeting the FTO Protein May Improve Cancer Treatment Outcomes in Future Trials
This systematic review examines the role of FTO as a context-dependent epitranscriptomic regulator in cancer. The authors conclude that whil…
Scientists are looking at how targeting a specific protein called FTO could help patients who receive immunotherapy for cancer.
Review: Targeting mRNA Processing Enhances Immune Checkpoint Blockade in Cancer
New cancer treatments target RNA to boost immune system power
This review examines strategies targeting mRNA processing (alternative splicing, RNA modifications, RNA editing) combined with immune checkp…
Scientists found that combining RNA processing strategies with immune checkpoint blockade creates powerful synergistic effects for treating …