Anti-interferon-gamma autoantibody-associated immunodeficiency may explain severe melioidosis and necrotic skin lesions
New immune condition may explain severe cases of melioidosis infection
This case report and literature review describes a 66-year-old woman with melioidosis and anti-interferon-gamma autoantibody-associated immu…
A rare immune deficiency linked to specific antibodies may explain why some patients suffer severe skin lesions and internal infections from…
Cefepime-nacubactam and aztreonam-nacubactam non-inferior for complicated UTI and pyelonephritis
New antibiotics show promise for complicated urinary tract infections
This phase 3 randomised double-blind study in adults with complicated urinary tract infection or acute uncomplicated pyelonephritis found ce…
A large trial found new antibiotic combinations worked better than standard care for certain urinary infections in adults.
Brief research report on toxicity-guided TMP-SMX dose reduction in disseminated nocardiosis
Gold miner's rare infection treated with adjusted antibiotic dose
This brief research report describes a single case of disseminated nocardiosis with CNS involvement in a patient with pneumoconiosis.
A gold miner with a rare brain infection improved after doctors lowered his antibiotic dose due to severe side effects.
Meta-analysis of antimicrobial resistance prevalence in Tanzanian hospital pathogens
Common Antibiotics Are Failing in Tanzania, New Data Reveals
This systematic review and meta-analysis synthesizes data from 28 studies on antimicrobial resistance in clinically relevant pathogens withi…
This research shows that common antibiotics are losing their power in Tanzania, urging a critical update to how infections are treated.
Retrospective cohort study assesses Acinetobacter baumannii prevalence and resistance in ventilator-associated infections
ICU Infection Risk Skyrockets Without Local Drug Data
This retrospective observational cohort analyzed 3,540 non-duplicate clinical isolates from a tertiary-care ICU in South India.
ICU patients with breathing tubes face higher infection risks when doctors lack fresh local data on which antibiotics actually work against …