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Home › Conditions › complicated urinary tract infection

Complicated urinary tract infection

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for complicated urinary tract infection

17 trials tracked for complicated urinary tract infection: 11 in phase 3 or 4 and 7 with published results. The most-cited published study has 439 citations.

17Trials tracked
11Phase 3 & 4
0Recruiting
7With published results
Phase distribution
Phase 3 11 Phase 2 5 Other / NA 1
  1. Phase 3 Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults Completed · 439 cited
  2. Phase 3 Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP Completed · 306 cited
  3. Phase 3 A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP) Completed · 210 cited
  4. Phase 3 Safety and Efficacy of ZTI-01 (IV Fosfomycin) vs Piperacillin/Tazobactam for Treatment cUTI/AP Infections Completed · 138 cited
  5. Phase 3 Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) Completed · 73 cited
  6. Phase 3 Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) in Japanese Participants With Complicated Intra-abdominal Infection or Complicated Urinary Tract Infection (MK-7655A-017) Completed · 24 cited
Show 11 more trials
  1. Phase 3 Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in Subjects With Complicated Urinary Tract Infections or Acute Uncomplicated Pyelonephritis Completed · 1 cited
  2. Phase 3 Study of Ceftolozane/Tazobactam (MK-7625A) in Japanese Participants With Uncomplicated Pyelonephritis and Complicated Urinary Tract Infection (MK-7625A-014) Completed
  3. Phase 3 Study of Cefepime-zidebactam (FEP-ZID) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) Completed
  4. Phase 3 Ceftazidime-Avibactam for the Treatment of Infections Due to Ceftazidime Resistant Pathogens Completed
  5. Phase 3 Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Levofloxacin in Complicated Urinary Tract Infection, Including Pyelonephritis Completed
  6. Phase 2 Comparative Study of NXL104/Ceftazidime Versus Comparator in Adults With Complicated Urinary Tract Infections Completed
  7. Phase 2 Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infections Completed
  8. Phase 2 MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034) Completed
  9. Phase 2 Safety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract Infections Completed
  10. Phase 2 A Study of Plazomicin Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP) Completed
  11. N/A Clinical Utility of a PCR Compared to Culture and Sensitivity Testing for the Management of cUTI in Adults. Completed

Showing the 17 most-cited and recently-updated of 17 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Cefepime-nacubactam and aztreonam-nacubactam non-inferior for complicated UTI and pyelonephritis
Infectious Disease RCT
Cefepime-nacubactam and aztreonam-nacubactam non-inferior for complicated UTI and pyelonephritis New antibiotics show promise for complicated urinary tract infections
This phase 3 randomised double-blind study in adults with complicated urinary tract infection or acute uncomplicated pyelonephritis found ce…
A large trial found new antibiotic combinations worked better than standard care for certain urinary infections in adults.
May 16, 2026