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Home › Medications › imiquimod

imiquimod

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of imiquimod

17 trials tracked of imiquimod: 5 in phase 3 or 4 and 2 with published results. The most-cited published study has 463 citations.

17Trials tracked
5Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 3 5 Phase 2 6 Phase 1 4 Other / NA 2
  1. Phase 3 Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions Completed · 463 cited
  2. Phase 3 Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions Completed · 3 cited
  3. Phase 3 A Study to Evaluate the Safety and Efficacy Imiquimod Cream, 2.5% in Participants With Actinic Keratoses Completed
  4. Phase 3 Bioequivalence of Generic Imiquimod Cream, 5% When Compared to Aldara™ (Imiquimod) Cream, 5% in the Treatment of Actinic Keratosis Completed
  5. Phase 3 Safety and Effectiveness Study of Imiquimod Creams in the Treatment of External Genital Warts Completed
  6. Phase 2 Evaluation of the Impact of Adjuvants Accompanying Peptide Immunization in High-Risk Melanoma Completed
Show 11 more trials
  1. Phase 2 Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme Completed
  2. Phase 2 Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3) Completed
  3. Phase 2 Topical Imiquimod and Abraxane in Treating Patients With Advanced Breast Cancer Completed
  4. Phase 2 Toll-like Receptor (TLR) 7 Agonist, Cyclophosphamide, and Radiotherapy for Breast Cancer With Skin Metastases Completed
  5. Phase 2 Imiquimod for Breast Cancer Patients With Chest Wall Recurrence or Skin Metastases Completed
  6. Phase 1 Topical Fluorouracil and Imiquimod in Treating Patients With High-Grade Cervical Intraepithelial Neoplasia Completed
  7. Phase 1 Imiquimod and Pembrolizumab in Treating Patients With Stage IIIB-IV Melanoma Completed
  8. Phase 1 NY-ESO-1 Protein Vaccine With Imiquimod in Melanoma (Adjuvant Setting) Completed
  9. Phase 1 Therapeutic Vaccination for Patients With HPV16+ Cervical Intraepithelial Neoplasia (CIN2/3) Completed
  10. N/A Topical Imiquimod in Treating Patients With Recurrent Paget's Disease of the Vulva Completed
  11. N/A Combining Topical Imiquimod 5% Cream With a Pulsed Dye Laser to Treat Port Wine Stain Birthmarks Completed

Showing the 17 most-cited and recently-updated of 17 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Imiquimod TLR7 stimulation shows sex-specific immune responses in HIV and non-HIV populations
Allergy & Immunology Cohort
Imiquimod TLR7 stimulation shows sex-specific immune responses in HIV and non-HIV populations Research shows immune reactions to imiquimod vary between men and women with HIV
This cohort study evaluated TLR7 stimulation with imiquimod in 1,326 individuals living with HIV and 43 people without HIV.
Women with HIV show different immune reactions to imiquimod than men, suggesting doctors may need to consider biological sex when developing…
Frontiers Apr 21, 2026
Imiquimod costs substantially less than radiotherapy for lentigo maligna in Australian analysis
Dermatology RCT
Imiquimod costs substantially less than radiotherapy for lentigo maligna in Australian analysis Study finds topical treatment for lentigo maligna costs far less than radiotherapy
A phase 3 RCT-based cost analysis of 118 patients with lentigo maligna found imiquimod had dramatically lower healthcare system (US$72.50 vs…
Topical cream costs just $72 per patient versus over $2,600 for radiotherapy when treating lentigo maligna, a sun-damaged skin condition.
Apr 1, 2026