How many clinical trials are tracked for Human Papillomavirus Infection?

30 trials are tracked, 5 with published results.

Human Papillomavirus Infection Research

Human Papillomavirus Infection: what the trials found

Multiple trials evaluated the efficacy and immunogenicity of various HPV vaccines, including Gardasil, Cervarix, and V503 (9-valent human papillomavirus L1 virus-like particle vaccine). Clinical data demonstrate high seropositivity rates for these vaccines; specifically, 100% of participants were seropositive for HPV types 6/11/16/18 in several studies [4, 5, 14]. V503 demonstrated significant geometric mean titers (GMTs) against various HPV types including 6, 11, 16, and 18 across multiple trials [4, 6, 8], with some results showing high statistical significance (p < 0.001).

Comparative studies for Gardasil showed a significantly lower incidence of disease related to HPV types 31/33/45/52/58 compared to the control group ⁹. Additionally, trials evaluating Cervarix and other vaccine formulations reported high rates of successful seroconversion and meeting acceptable antibody titers for associated conditions like diphtheria and tetanus [10, 11].

One study specifically assessed the impact of modified vaccination schedules on completion rates among female sex workers; no significant difference was found in completion rates between a 3-month and 6-month schedule (p=0.60), nor were there significant differences in the prevalence of HPV infection between groups ³.

For the clinician treating this condition

HPV vaccines (Gardasil, Cervarix, and V503) consistently demonstrate high seropositivity and robust antibody responses against major HPV types.
V503 shows statistically significant geometric mean titers across multiple study cohorts for protection against various HPV strains.
Modified vaccination schedules did not significantly impact the completion rates of the vaccine series in specific populations.

AI synthesis of 4 cited trials, updated Jun 25, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.