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Home › Medications › L-citrulline

L-citrulline

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of L-citrulline

2 trials tracked of L-citrulline: 1 in phase 3 or 4.

2Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 3 1 Phase 2 1
  1. Phase 3 L-citrulline for Prevention of Sequelae of Acute Lung Injury in Pediatrics Undergoing Cardiopulmonary Bypass for Heart Defects Completed
  2. Phase 2 Intravenous L-Citrulline Influence on the Need for Invasive Mechanical Ventilation for Acute Hypoxemic Respiratory Failure in Patients With COVID-19 Completed

Showing the 2 most-cited and recently-updated of 2 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
L-citrulline with HIIT alters specific microRNAs in obese older adults
Diabetes & Endocrinology RCT
L-citrulline with HIIT alters specific microRNAs in obese older adults How 12 Weeks of Hard Exercise Changes the Molecular Machinery of Aging Muscle
A secondary exploratory analysis of a double-blind randomized trial in 68 obese older adults found that 12-week HIIT with L-citrulline suppl…
A 12-week high-intensity interval training program produced measurable molecular changes in older adults' muscles — and a natural supplement…
Apr 14, 2026
Review suggests L-citrulline plus leucine with exercise may improve muscle and vascular health in elderly
Psychiatry Cohort
Review suggests L-citrulline plus leucine with exercise may improve muscle and vascular health in elderly Can a simple supplement combo with exercise help older adults stay stronger?
A review of clinical and experimental research in elderly populations suggests concurrent L-citrulline and leucine supplementation with stru…
Combining L-citrulline and leucine supplements with exercise boosts muscle mass, vascular function, and physical performance in older adults…
Frontiers Apr 3, 2026