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Home › Medications › losartan

losartan

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials of losartan

52 trials tracked of losartan: 26 in phase 3 or 4 and 5 with published results. The most-cited published study has 30 citations.

52Trials tracked
26Phase 3 & 4
0Recruiting
5With published results
Phase distribution
Phase 4 11 Phase 3 15 Phase 2 14 Phase 1 7 Other / NA 5
  1. Phase 4 Do Angiotensin Receptor Blockers Mitigate Progression to Acute Respiratory Distress Syndrome With SARS-CoV-2 Infection Completed · 30 cited
  2. Phase 4 Losartan Effects on Emphysema Progression Completed · 26 cited
  3. Phase 3 MK-0954E Study in Participants With Hypertension (MK-0954E-357) Completed · 12 cited
  4. Phase 4 N-of-1 Trials In Children With Hypertension Completed · 9 cited
  5. Phase 4 Fixed Dose Intervention Trial of New England Enhancing Survival in SMI Patients Completed · 2 cited
  6. Phase 4 Efficacy of Losartan in Preventing Progression of COPD Completed
Show 44 more trials
  1. Phase 4 Olmesartan Comparison to Losartan in Hypertensive Subjects Completed
  2. Phase 4 LAAS (Losartan Anti-Atherosclerosis Study)(0954-330)(COMPLETED) Completed
  3. Phase 4 Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy Volunteers Completed
  4. Phase 4 A Randomized Clinical Trial To Study Losartan On Endothelial Dysfunction and Insulin Resistance In Obese Patients Completed
  5. Phase 4 ALiskiren or Losartan Effects on bioMARKers of Myocardial Remodeling Completed
  6. Phase 4 Comparison Between Losartan and Benazepril in Diabetic Hypertensive Patients Not Controlled by Amlodipine Completed
  7. Phase 3 Efficacy and Safety Evaluating Study to Compare Kanarb (Fimasartan) and Cozaar® (Losartan) in Adult Patients With Grade I-II Arterial Hypertension Completed
  8. Phase 3 An Efficacy and Safety Study in Children 6 to Less Than 18 Years of Age With Hypertension Completed
  9. Phase 3 Study of Losartan in Pediatric Patients With Hypertension (MK-0954-337) Completed
  10. Phase 3 Olmesartan Medoxomil Versus Losartan in Patients With Hypertension Completed
  11. Phase 3 A Study to Investigate the Magnitude and Duration of Response of MK0954 Compared to Placebo in Patients With Hypertension (0954-021)(COMPLETED) Completed
  12. Phase 3 A Study to Investigate the Antihypertensive Efficacy of MK0954 Completed
  13. Phase 3 Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome Completed
  14. Phase 3 Renoprotection in Early Diabetic Nephropathy in Pima Indians Completed
  15. Phase 3 MK0954 Versus Placebo for Treatment of Mild to Moderate Hypertension Completed
  16. Phase 3 Efficacy and Safety of Valsartan in Combination With Amlodipine Compared to Losartan Plus Hydrochlorothiazide in Patients With Hypertension and Left Ventricular Hypertrophy Completed
  17. Phase 3 A Study to Investigate the Efficacy and Safety of Different Doses of Losartan Potassium (MK0954-011) Completed
  18. Phase 3 MK-0954A in Japanese Patients With Essential Hypertension Not Adequately Controlled With Losartan (MK-0954A-352) Completed
  19. Phase 3 An Extension Study Designed to Assess Effects of Losartan on Proteinuria in Pediatric Populations (MK-0954-326 AM1,EXT1(AM2)) Completed
  20. Phase 3 Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome Completed
  21. Phase 2 An Open-Label Trial of Losartan Potassium in Participants With Eosinophilic Esophagitis (EoE) Completed
  22. Phase 2 The ENRGISE (ENabling Reduction of Low-Grade Inflammation in SEniors) Pilot Study Completed
  23. Phase 2 Losartan for Patients With COVID-19 Requiring Hospitalization Completed
  24. Phase 2 Study of Losartan in the Treatment of NAFLD in Children Completed
  25. Phase 2 Effect of Losartan in Patients With Nonobstructive Hypertrophic Cardiomyopathy Completed
  26. Phase 2 Study of Cardiovascular Disease and Obstructive Sleep Apnea Completed
  27. Phase 2 Losartan to Reverse Sickle Nephropathy Completed
  28. Phase 2 Reversing Tissue Fibrosis to Improve Immune Reconstitution in HIV Completed
  29. Phase 2 Losartan for Patients With COVID-19 Not Requiring Hospitalization Completed
  30. Phase 2 Pilot Study of Losartan and N-acetylcysteine as Inhibitors of Muscle Oxidative Stress in Elderly Completed
  31. Phase 2 Testing Effectiveness of Losartan in Patients With EoE With or Without a CTD Completed
  32. Phase 2 A Study of Muscle Strength Maintenance in Older Adults Completed
  33. Phase 2 ACES - ACE Inhibitors Combined With Exercise for Seniors With Hypertension Completed
  34. Phase 2 Patiromer in the Treatment of Hyperkalemia in Patients With Hypertension and Diabetic Nephropathy (AMETHYST-DN) Completed
  35. Phase 1 Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors Completed
  36. Phase 1 Study of Open Label Losartan in COVID-19 Completed
  37. Phase 1 Losartan for Improved Vascular Endothelial Function After Preeclampsia Completed
  38. Phase 1 Losartan 100 mg Tablets in Healthy Subjects Under Fasting Conditions Completed
  39. Phase 1 The Effect of Losartan and Losartan Plus Isosorbide Mononitrate on Central Blood Pressure Measurements (0954-317) Completed
  40. Phase 1 Bioequivalence of Losartan and Hydrochlorothiazide (HCTZ) Combination Tablet and Coadministration of Its Components (0954A-306) Completed
  41. Phase 1 Losartan 100 mg Tablet in Healthy Subjects Under Non-Fasting Conditions Completed
  42. N/A Ambulatory vs Office BP Management Usual Care for Diagnosing and Managing Hypertension: A Pilot Study Completed
  43. N/A Losartan in Treating Patients With Idiopathic Pulmonary Fibrosis Completed
  44. N/A A Controlled Trial of Losartan in Posttraumatic Stress Disorder Completed

Showing the 50 most-cited and recently-updated of 52 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Losartan reduces incidence and delays onset of paclitaxel-induced peripheral neuropathy in women with early-stage breast cancer
Oncology RCT
Losartan reduces incidence and delays onset of paclitaxel-induced peripheral neuropathy in women with early-stage breast cancer Losartan may reduce nerve pain from breast cancer chemotherapy in small trial
This single-center, open-label randomized controlled trial enrolled 89 women with early-stage breast cancer scheduled for weekly paclitaxel.
A common blood pressure drug called losartan significantly reduced nerve pain and improved quality of life for women receiving breast cancer…
Apr 9, 2026