Targeted Therapies May Shift COPD Care Toward Precision Medicine
Targeted Therapies Offer New Options for Chronic Obstructive Pulmonary Disease
This systematic review examines emerging targeted therapies for COPD, including monoclonal antibodies, small-molecule modulators, and stem c…
New targeted treatments like monoclonal antibodies may offer better options for people with COPD who do not respond well to standard inhaler…
Monoclonal antibodies and various vaccine platforms show potential for human metapneumovirus prevention in children
New research explores ways to protect children from metapneumovirus
This narrative review examines the development of monoclonal antibodies and vaccines for human metapneumovirus (hMPV) in pediatric populatio…
Scientists are looking at new ways to protect children from metapneumovirus using both vaccines and monoclonal antibodies.
Splicing-derived neoantigens provide diverse target classes for T-cell and antibody-based cancer immunotherapies
Splicing-Derived Neoantigens Offer New Targets for Cancer Immunotherapy
This systematic review explores splicing-derived neoantigens as potential targets for cancer immunotherapy. The review identifies two major …
New research identifies splicing-derived neoantigens as a promising source of specific targets for T-cell and antibody-based cancer treatmen…
IL-37 and IL-38 act as endogenous regulators of CAR-T-associated hyperinflammation in multiple myeloma
New Proteins May Help Control Inflammation in Multiple Myeloma Treatment
This mini-review explores the roles of IL-37 and IL-38 as potential immunoregulatory checkpoints in patients with relapsed/refractory multip…
Two specific proteins, IL-37 and IL-38, may help control dangerous inflammation during CAR-T cell therapy for multiple myeloma.
IL-17 axis targeting shows substantial efficacy but faces cost and delivery hurdles
IL-17 blockers show promise for autoimmune diseases
This systematic review examines IL-17 axis targeting with monoclonal antibodies and small-molecule inhibitors across psoriasis, lupus, perio…
New review finds IL-17-targeting drugs work well for psoriasis and other conditions, but cost and side effects remain hurdles.
High-dose corticosteroids combined with IVIG or plasma exchange are preferred for triple-M syndrome
Triple-M Syndrome Linked to Immune Checkpoint Inhibitor Therapy
This systematic review of case reports and series examines the management of triple-M syndrome following immune checkpoint inhibitor therapy…
Patients receiving immune checkpoint inhibitors may develop triple-M syndrome, a serious combination of muscle, heart, and nerve issues requ…
Chemokine networks regulate triple-negative breast cancer tumor microenvironment but clinical translation remains limited
Chemokine Targets Show Promise in Lab but Face Clinical Hurdles
This systematic review examines the role of chemokine networks and targeted interventions in the triple-negative breast cancer immune microe…
New research highlights the role of chemokine networks in breast cancer, showing strong results in labs despite challenges in current clinic…
Type 2 monoclonal antibodies reduce annual moderate-to-severe exacerbations in patients with eosinophilic COPD
Monoclonal Antibodies Reduce Exacerbations in Patients with Eosinophilic COPD
This systematic review and meta-analysis of 3,171 patients found that type 2 monoclonal antibodies reduced the annual rate of moderate-to-se…
A review of clinical trials shows that type 2 monoclonal antibodies can reduce frequent flare-ups for patients with specific types of COPD.
AI-driven in silico tools enhance sequence design and optimization for monoclonal antibody development
Artificial intelligence speeds up discovery of new antibody treatments
This systematic review evaluates AI-driven in silico tools for the discovery and optimization of monoclonal antibodies across infectious, au…
New computer tools powered by AI help scientists design and optimize antibodies for diseases like cancer and autoimmune disorders faster.
Neuroinflammation-targeted immunotherapy shows no significant benefit in ischemic stroke meta-analysis
Trial Shows Neuroinflammation Therapies Lack Consistent Benefit for Stroke
This meta-analysis of 3 RCTs (637 patients) found no significant pooled clinical benefit for neuroinflammation-targeted immunotherapies in i…
New research into cell and antibody therapies for stroke shows that these treatments do not yet provide a consistent clinical benefit for pa…
Post-marketing data on CGRP inhibitors show paucity of data and additional risks from chronic biologic use
Post-marketing review highlights safety gaps for migraine CGRP drugs
This narrative review examines monoclonal antibodies and Calcitonin Gene-Related Peptide (CGRP) inhibitors for migraine in the post-marketin…
A review of migraine treatments notes limited data on long-term risks for CGRP inhibitors, urging caution during active monitoring.
Narrative review discusses antibody targeting of the TNF–TNFR2 axis in cancer with noted limitations
Antibodies targeting TNFR2 show promise for cancer treatment
This narrative review examines antibody targeting of the TNF–TNFR2 axis, including monoclonal antibodies, antibody–drug conjugates, and bisp…
A narrative review suggests antibodies targeting the TNF–TNFR2 axis may offer new cancer treatment options, though more research is needed.
All monoclonal antibodies Articles
- Targeted Therapies May Shift COPD Care Toward Precision Medicine
- Monoclonal antibodies and various vaccine platforms show potential for human metapneumovirus prevention in children
- Splicing-derived neoantigens provide diverse target classes for T-cell and antibody-based cancer immunotherapies
- IL-17 axis targeting shows substantial efficacy but faces cost and delivery hurdles
- IL-37 and IL-38 act as endogenous regulators of CAR-T-associated hyperinflammation in multiple myeloma
- High-dose corticosteroids combined with IVIG or plasma exchange are preferred for triple-M syndrome
- Chemokine networks regulate triple-negative breast cancer tumor microenvironment but clinical translation remains limited
- Type 2 monoclonal antibodies reduce annual moderate-to-severe exacerbations in patients with eosinophilic COPD
- AI-driven in silico tools enhance sequence design and optimization for monoclonal antibody development
- Neuroinflammation-targeted immunotherapy shows no significant benefit in ischemic stroke meta-analysis
- Post-marketing data on CGRP inhibitors show paucity of data and additional risks from chronic biologic use
- Narrative review discusses antibody targeting of the TNF–TNFR2 axis in cancer with noted limitations
- Meta-analysis finds trivial cognitive effects of amyloid antibodies in mild Alzheimer's disease