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naltrexone

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials of naltrexone

61 trials tracked of naltrexone: 22 in phase 3 or 4 and 6 with published results. The most-cited published study has 260 citations.

61Trials tracked
22Phase 3 & 4
0Recruiting
6With published results
Phase distribution
Phase 4 12 Phase 3 10 Phase 2 34 Phase 1 2 Other / NA 3
  1. Phase 4 Treatment for Alcoholism and Post-Traumatic Stress Disorder (Naltrexone) Completed · 260 cited
  2. Phase 4 Pharmacogenetic Response to Naltrexone For Alcohol Dependence Completed · 117 cited
  3. Phase 4 Managing Alcoholism in People Who Do Not Respond to Naltrexone Completed · 55 cited
  4. Phase 4 Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia Completed · 27 cited
  5. Phase 4 Prevention of Stimulant-Induced Euphoria With an Opioid Receptor Antagonist Completed · 11 cited
  6. Phase 3 Evaluating Naltrexone for Use in Conjunction With Buprenorphine in Adults With Opioid Use Disorder Transitioning From Buprenorphine Maintenance Prior to First Dose of VIVITROL Completed · 8 cited
Show 44 more trials
  1. Phase 4 An Open-Label Study of Naltrexone in Adults With Attention Deficit Hyperactivity Disorder. Completed
  2. Phase 4 Control of Cognition (Naltrexone, Methylphenidate, and ADHD Study (NMAS)) Completed
  3. Phase 4 Endophenotype for Alcohol Misuse in Healthy Minority Populations Completed
  4. Phase 4 Understanding Treatment Response With Naltrexone Among White Alcoholics Completed
  5. Phase 4 Naltrexone for Heavy Drinking in Young Adults Completed
  6. Phase 4 Naltrexone for Impulse Control Disorders in Parkinson's Disease Completed
  7. Phase 4 Effectiveness of Naltrexone Versus Placebo to Reduce Craving for Alcohol With Evaluation of Genetic Variability. Completed
  8. Phase 3 Treatment Strategy for Alcohol Use Disorders in Veterans With TBI Completed
  9. Phase 3 Clinical Trial to Reduce Drinking in Women With HIV Completed
  10. Phase 3 Drug Treatment for Pathologic Gambling Disorder Completed
  11. Phase 3 Oral vs. Injectable Naltrexone for Hospitalized Veterans With Alcohol Dependence Completed
  12. Phase 3 Reducing Heavy Drinking to Optimize HIV/AIDS Treatment and Prevention Completed
  13. Phase 3 Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep Completed
  14. Phase 3 Effects of Omegas 3 and 6 on Alcohol Dependence Completed
  15. Phase 3 Naltrexone & SSRI in Alcoholics With Depression/PTSD Completed
  16. Phase 3 Effectiveness of Gabapentin When Used With Naltrexone to Treat Alcohol Dependence Compared to Placebo and Naltrexone Alone Completed
  17. Phase 2 Memantine and Naltrexone Treatment for Opioid Dependence Completed
  18. Phase 2 Naltrexone in the Treatment of Trichotillomania Completed
  19. Phase 2 Modafinil and Naltrexone to Reduce Cocaine and Alcohol Dependence Completed
  20. Phase 2 Naltrexone and Hypoglycemia in Type 1 Diabetes Completed
  21. Phase 2 A Novel Human Lab Model for Screening AUD Medications Completed
  22. Phase 2 Effect of Topical Naltrexone Ophthalmic Solution on the Signs and Symptoms of Dry Eye in Diabetic Subjects Completed
  23. Phase 2 Naltrexone for Individuals of East Asian Descent Completed
  24. Phase 2 The Effect of Naltrexone and Varenicline on Alcohol-Mediated Smoking Lapse Completed
  25. Phase 2 Medication Development in Alcoholism: Acamprosate Versus Naltrexone Completed
  26. Phase 2 Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home Completed
  27. Phase 2 Intermittent Oral Naltrexone Enhanced With an Ecological Momentary Intervention for Methamphetamine-using MSM Completed
  28. Phase 2 Medications for Stopping Cocaine Dependence and Preventing Relapse Completed
  29. Phase 2 Effects of Naltrexone on Nicotine Reinforcement Completed
  30. Phase 2 Naltrexone for At-Risk and Problem Drinking in Smoking Cessation Treatment Completed
  31. Phase 2 An Open Label Trial of Bupropion and Naltrexone for Binge Drinking Completed
  32. Phase 2 Optimizing Pharmacotherapy for Bipolar Alcoholics Completed
  33. Phase 2 The Efficacy of Low Dose Naltrexone Therapy in Children With Crohn's Disease Completed
  34. Phase 2 Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain Completed
  35. Phase 2 Sweet Preference and Alcohol Craving Completed
  36. Phase 2 Better Than Study: Targeting Heavy Alcohol Use With Naltrexone Among Men Who Have Sex With Men (MSM) Completed
  37. Phase 2 An Exploratory Study of Naltrexone Plus Aripiprazole for Alcohol Dependence Completed
  38. Phase 2 Opioid Modulation and Neural Reward Activation in Healthy Adults Completed
  39. Phase 2 Double-Blind Naltrexone in Kleptomania Completed
  40. Phase 2 Effects of Low-dose Naltrexone in Combination With a Range of Smoked Marijuana Completed
  41. Phase 2 Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate Completed
  42. Phase 2 Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders Completed
  43. Phase 2 Naltrexone and Varenicline: Weight Gain and Tolerability in Cigarette Smokers Completed
  44. Phase 2 Low Dose Naltrexone for Chronic Pain From Arthritis Completed

Showing the 50 most-cited and recently-updated of 61 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.