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Home › Medications › orlistat

orlistat

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of orlistat

9 trials tracked of orlistat: 5 in phase 3 or 4 and 1 with published results. The most-cited published study has 114 citations.

9Trials tracked
5Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 4 Phase 3 1 Phase 2 3 Other / NA 1
  1. Phase 3 Improving Reproductive Fitness Through Pretreatment With Lifestyle Modification in Obese Women With Unexplained Infertility Completed · 114 cited
  2. Phase 4 Weight Loss Aid in an Exposed Population Completed
  3. Phase 4 A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in America Completed
  4. Phase 4 A Pilot Study of the Efficacy of Alli in the Management of Pre-operative Weight Loss Required for Bariatric Surgery. Completed
  5. Phase 4 Effect of Orlistat in Body Composition Completed
  6. Phase 2 The Effect of Liraglutide on Body Weight in Obese Subjects Without Diabetes Completed
Show 3 more trials
  1. Phase 2 Safety and Efficacy of Xenical in Children and Adolescents With Obesity-Related Diseases Completed
  2. Phase 2 Orlistat for the Treatment of Type I Hyperlipoproteinemia Completed
  3. N/A A Low-Carbohydrate, Ketogenic Diet Versus Orlistat for Weight Loss Completed

Showing the 9 most-cited and recently-updated of 9 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Age over 50 and alcohol use are risk factors for severe orlistat-induced liver injury
Drug Pipeline Sys. Review
Age over 50 and alcohol use are risk factors for severe orlistat-induced liver injury Risk Factors for Liver Injury Linked to Orlistat Use
This systematic review of case reports examines the clinical spectrum and risk factors for orlistat-induced liver injury (OILI). The analysi…
Specific risk factors like age and alcohol use may increase the chance of severe liver issues in patients taking the weight loss medication …
Frontiers Jul 25, 2026
Network Meta-Analysis Finds Tirzepatide and Sleeve Gastrectomy Equally Effective for Weight Loss in Obesity
Diabetes & Endocrinology Meta-analysis
Network Meta-Analysis Finds Tirzepatide and Sleeve Gastrectomy Equally Effective for Weight Loss in Obesity New Weight Loss Pill Matches Surgery Results Without the Scalpel
A network meta-analysis of 14,293 adults with obesity found that tirzepatide 10 or 15 mg and sleeve gastrectomy achieved similar weight loss…
A diabetes drug now pulls even with stomach surgery for weight loss offering hope to millions who dread going under the knife but it is not …
May 4, 2026
Network Meta-Analysis Finds Tirzepatide and Semaglutide Most Effective for Weight Loss in Adults
Diabetes & Endocrinology Meta-analysis
Network Meta-Analysis Finds Tirzepatide and Semaglutide Most Effective for Weight Loss in Adults New Weight Loss Drugs Protect Your Heart and Lower Death Risk
A systematic review and network meta-analysis of 63,909 adults found that all obesity medications produced greater weight loss than placebo.
New data from 66 trials shows top obesity drugs significantly reduce heart events and death while helping with liver and joint pain issues f…
medRxiv Apr 24, 2026